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Pre-Clinical Models: Advancing Medical Knowledge and Making Human Trials Safer

- This event is a production of the Atlanta Science Tavern and is part of our Young Researchers series.
- Our Open Seating Policy will be in effect and seating will be on a first-come basis.
- The capacity of the North Avenue Room is 40. We expect a turnout of approximately 50% of day-of RSVPs.
- Arrive by 7:00 pm or earlier to place your drink or dinner orders. The presentation will get underway when the food is served.
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Pre-Clinical Models: Advancing Medical Knowledge and Making Human Trials Safer

Alice Li, Doctoral student
Wallace H. Coulter Department of Biomedical Engineering
Georgia Tech / Emory University

Tanushree Thote, Doctoral Student
Wallace H. Coulter Department of Biomedical Engineering
Georgia Tech / Emory University / Peking University 

Before drugs or other types of medical procedures can be tested in humans, work has to be done to ensure their safety and effectiveness. Using animals for such testing, often referred to as pre-clinical models, has met with much success since the 1920s and has accounted for much of the increase in average life expectancy since that time.

This talk will begin with a brief overview of preclinical studies, including a short discussion of the ethics of animal experimentation. Alice will tell us about her research on how to establish a composite bone and muscle injury model which has implications for tissue engineering strategies for limb regeneration. Tanushree will discuss testing therapeutics related to her research which focuses on examining the changes in cartilage during the progression of osteoarthritis.

About our speakers

Alice Li is a doctoral student in the Wallace H. Coulter Department of Biomedical Engineering, pursuing a joint PhD degree from Georgia Tech and Emory University. She graduated with a Bachelor’s degree in Biomedical Engineering from the University of Texas at Austin. Alice's research includes establishing a composite bone and muscle injury model as well as investigating tissue engineering strategies for limb regeneration.

Tanushree Thote is a doctoral student in the Wallace H. Coulter Department of Biomedical Engineering pursuing a joint PhD program at Georgia Tech, Emory University and Peking University. She graduated with a Bachelor’s degree in Biological Engineering from University of Arkansas, Fayetteville. Her research focuses on examining the changes in cartilage during the progression of osteoarthritis by using non-invasive methods. 

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