MASSEP.org and the GBMSDG invite you to attend the 15th Annual
Symposium on Advances in Separation Science and Mass Spectrometry
Schedule of Events
1:00-1:30 PM Poster set up
1:00-3:00 PM Registration/vendor exhibition/posters in the Curry Center
3:00-4:00 PM Plenary lecture 1: Prof. Graham Cooks, Purdue Univ. Dept of Chemistry, West Lafayette, IN, presenting “Quant. by Ambient Ioniz.: Drugs in Whole Blood, Lipids in Tissue”
4:00-5:00 PM Plenary lecture 2: Prof. Pauline Rudd, The National Institute for Bioprocessing Research and Training (NIBRT) in Dublin, Ireland, presenting “Automated Glycan Analysis for Integrated Biology”
5:00-6:30 PM Reception with refreshments, Exhibition and Posters
For Registration go to http://www.massep.org
Call for Abstracts:
Abstracts in the areas of liquid chromatography, capillary electrophoresis and mass
spectrometry can be submitted on-line at
Posters may be from your previously published work from the last year.
Awards for best poster: $250 for first place and $100 for second place.
The deadline for submission of abstracts is April 24, 2013.
Space is limited so please submit soon.
For more information see the MASSEP.org Website at www.massep.org
Speaker Abstracts and Bios:
Graham Cooks received Ph. D. degrees from the University of Natal (now KwaZulu-Natal) and Cambridge University. His interests involve construction of mass spectrometers and their use in fundamental studies and applications. Early in his career, he contributed to the concept and implementation of tandem mass spectrometry and to desorption ionization, described the first matrix assisted ionization, new types of MS scans including multiple reaction monitoring, and the first hybrid instruments. His interest in minimizing sample work-up and avoiding chromatography contributed to the development of the ambient ionization methods, including desorption electrospray ionization (DESI). These same interests also led to the construction of miniature ion trap mass spectrometers and their application to problems of trace chemical detection. His interests in the fundamentals of ion chemistry include chiral analysis and spontaneous chiral resolution in amino acid clusters. Graham Cooks is a past President of the American Society for Mass Spectrometry and the International Mass Spectrometry Society and Life Member of the British Mass Spectrometry Society. He has worked with several hundred collaborators from around the world including a 125 Ph. D. students
Abstract for Prof Cooks' Talk:
A minor revolution is occurring in mass spectrometry with the growing recognition that it is possible to simplify sample preparation and yet obtain high quality chemical information on complex real-world samples. At the core of this development is a set of ambient ionization experiments in which ionization is performed in air, outside the mass spectrometry, on samples in their native form. Starting with the use of a charged spray (desorption electrospray ionization, DESI) in 2004, implementation has included plasmas, lasers and thermal agents. The fundamentals of DESI and the paper spray method are reviewed. Applications to imaging and diagnostics of tissue, to microorganism typing and to the quantitative analysis of therapeutics in whole blood are presented. Comparisons with traditional LC/MS/MS methods of trace quantitative analysis are made. The current state of development of miniature mass spectrometers, especially their use as portable instruments for point-of-care applications is described. Advanced methods in which chemical derivatization accompanies ambient ionization are shown as is the acceleration of chemical reaction rates in thin films and droplets encountered in mass spectrometry. Product formation at mg/min rates is described in the case of simple organic reactions and extension of preparative mass spectrometry to biological reactions is discussed.
Professor Pauline M. Rudd BSc, LRIC, MA (Oxon), PhD is the NIBRT Professor of Glycobiology at University College, Dublin. She heads the Dublin-Oxford Glycobiology Laboratory Research Group at the National Institute for Bioprocessing Research and Training in Ireland. The group has developed a platform technology for high throughput, detailed, quantitative glycan analysis suitable for analysing and monitoring the production of glycosylated therapeutics. This technology has also, for the first time, allowed glycomics data to be integrated with data from other high throughput ‘omics platforms such as Genome Wide Association Screening. The current applied programme is focused towards the needs of the Biopharmaceutical Bioprocessing Industry and also towards identifying and testing robust glycan-related disease biomarkers, particularly for cancer, congenital disorders of glycosylation and autoimmune disease. The basic research programme is targeted towards understanding the pathways which control glycan processing in disease to obtain a deeper understanding of multi-systemic diseases such as cancer.
Professor Rudd obtained a BSc in Chemistry at the University of London and a PhD in Glycobiology at the Open University, UK. She was a Founding Scientist of Wessex Biochemicals (later Sigma London), Visiting Research Associate at The Scripps Research Institute, CA, a Visiting Professor of Biochemistry at Shanghai Medical University PRC, Visiting Scientist at Ben Gurion University of the Negev, Israel and Erskine Visiting Fellow, Canterbury University, Christchurch, New Zealand. She is a Fellow of the Royal Society of Medicine, London and an Adjunct Professor at North Eastern University, Boston. She has more than 250 scientific publications and given over 200 lectures and in 2010 she was presented with a Thought Leader award from Agilent and gave a James Gregory Medal Lecture at St. Andrews University, Scotland.
Before moving her group to Dublin in 2006, Professor Rudd was a member of the Glycobiology Institute for 25 years. When she left she was a Senior Research Fellow and a University Reader in Glycobiology at Oxford University.
Student Members of MASSEP.org $5
Professional Members of MASSEP.org $10
Members of the GBMSDG $10
Symposium Registration: http://www.massep.org/Registration/Symposium.php