Illumina Sequencer Tearddown.. with Frickin' Lasers!

The defining characteristic of our exponentially increasing capability
in biology is the ease with which we are now able to sequence DNA. At
the forefront of this is Illumina. Their sequencers power two thirds
of the world market. Although there are competitors in the desktop
sequencing market, on the high end, high throughput machines Illumina
is clearly the frontrunner. These machines cost hundreds of thousands
of dollars, so it's not like peeking into the cover of your computer.
One of these machines is in the back room at BioCurious just waiting
to satisfy our curiosity!

On April 28th, at noon, you have the opportunity to come help take
apart an Illumina Genome Analyzer. We'll start with a discussion on
next generation sequencing to make sure everyone understands the
theory, then we'll dig into the machine. What optics are used? How is
the chemistry moved around? What imaging and electronics components
are used? How is the system assembled? The beast uses a combination
of microscopy, robotics, molecular biology, lasers, optics, high speed data
transfer, protein engineering, big data, and of course genomics... At the
end of the day, this spectacular machine will be laid bare. You'll see where
the magic happens and help us decide if i's possible for DIYbio makers
to hack a lower - cost DIY version.

Nowhere else in the world do you have the opportunity to break out a
screwdriver and help take apart this type of machine, only a couple years
back from the absolute state of the art. If you've ever wondered about
the intersection of manufacturing, electronics, chemical and
biological engineering that is driving the genome sequencing race,
this is your chance. We're keeping space limited so that everyone can
have a chance to get up close and participate, so sign up quickly at
the meetup page.

Hope to see you there, and bring your tool kit!

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  • Dave C.

    This is listed on the biocurious calendar for 7/28, is this happening again, or is it a typo?

    July 26, 2013

  • mithu

    would love to attain it!

    July 8, 2013

  • Daen de L.

    Thanks for organizing this -- it was enormously entertaining & educational, and great fun to hang out with such awesome folks!

    May 2, 2013

  • Tito J.

    Great seeing everyone! I wrote up my thoughts here: http://titojankowski.com/the-50...­

    Upload your Photos on Flickr!
    http://www.flickr.com/photos/bi...­
    Tito

    May 2, 2013

  • mac c.

    This sounds fantastic. What aspects of the meetup does the $75 fee cover? Are we renting a machine from a rep or something?

    April 22, 2013

    • Russell W.

      $75 is a bargain, practically free; I just recently spent a _lot_ of tuition money and a few years to play with these myself; looking forward to hearing how this went.

      April 22, 2013

    • mac c.

      Thanks Derek, great event. Looking forward to creative uses of the xy-stage and scanning lasers. Seems like high-performance scanning microscopy applications are in reach.

      April 28, 2013

  • Russell W.

    Which model is this exactly?

    April 22, 2013

    • Derek J.

      This is the Illumina GA (not the current model GA IIx)

      April 22, 2013

    • Russell W.

      Thanks Derek, appreciated.

      April 22, 2013

  • James W.

    Is it possible to increase the audience size and/or schedule another event? Have friends that would also like to attend.

    April 22, 2013

    • Derek J.

      this is the first of what will hopefully be a series of these. Please expect this first one to be less polished and more of a workshop and as the series progresses will begin to look more like a class.

      April 22, 2013

  • Cindy B.

    I may bring one more.

    April 22, 2013

    • Jenney

      Hi Cindy, bec of the limited numbers for this special event we need a firm RSVP.

      April 22, 2013

13 went

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