Currently #6 on BGG's Top 100 list, Power Grid is an elegant blend of auctions, tech advancement, supply-and-demand economics, and territory grabbing. The object of Power Grid is to supply the most cities with power when someone's network gains a predetermined size. Players mark pre-existing routes between cities for connection, and then bid against each other to purchase the power plants that they use to power their cities. However, as plants are purchased, newer, more efficient plants become available, so by merely purchasing, you're potentially allowing others access to superior equipment. Additionally, players must acquire the raw materials (coal, oil, garbage, and uranium) needed to power said plants (except for the 'renewable' windfarm/solar plants, which require no fuel), making it a constant struggle to upgrade your plants for maximum efficiency while still retaining enough wealth to quickly expand your network to get the cheapest routes.
I plan to use the USA map, but anybody else who has a set is welcome to post which map they want to play, and for how many players. I'll up the corresponding RSVP limit.
The BGG entry for "Power Grid": http://boardgamegeek.com/boardgame/2651/power-grid
The Rio Grande page: http://www.riograndegames.com/games.html?id=5