How can we do the most good in the world? What are the best charities? Which causes are most important? How can we best use our money and time to make a difference? And how do we do that without going nuts? Let's get together and talk about that.
Some useful sources on the topic:
80,000 Hours, a career resource for those interested in effective altruism
GiveWell, a charity evaluator
Giving What We Can, a giving community