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Decision Making and Quality Control in Early Moments of a Protein's Life

Proteins are the workhorses that carry out the vast majority of our cellular functions. and their proper production and balance is essential for the survival of all cells.  The first few moments of a protein emerges from the ribosome, the protein-synthesis machinery of the cell.  Just as the first three years of a child's development have a profound impact on the rest of his/her life, the first new moments of a protein's life has a profound impact on its future.  During those initial seconds to minutes, the newly synthesized protein must be precisely identified, engaged with the proper cellular machinery and committed to the correct biological pathways.  This talk will look at examples of research done at Caltech and elsewhere that illustrate how cells are able to make these decisions and assert quality control so early in a protein's life.

About Dr. Shu-ou Shan, Professor of Chemistry, Caltech:

This is one of the nine lectures in the Watson Lecture Series,named for the late Earnest C. Watson, who founded the series in 1922, featuring speakers from Caltech and JPL, speaking on cutting-edge research taking place at Caltech. Our gratitude to Earnest C. Watson, Richard C. Biedebach, and Arnold and Mabel Beckman for their contributions in making possible this free lecture to the public.

Admission is free on a first-come, first-served basis.
Doors open at 7:30pm.
For wheelchair seating services, call 626.395.4652.

Location and Parking Map:
Beckman Auditorium at CalTech in Pasadena.

Michigan Avenue south of Del Mar Boulevard, Pasadena., click on "Directions" located on left panel.

Parking is available in the lots south of Del Mar Boulevard between Wilson and Chester Avenues, as well as in the parking structures at 341 and 405 South Wilson Avenue, and 370 South Holliston Avenue.  Parking is free, with no permit required, after 5:00pm on weekdays and all day on weekends.

Beckman Auditorium Seating Map:

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  • A former member
    A former member

    It was interesting, I thought the lecture was going to take an evolutionary perspective.

    May 23, 2013

  • malcolm

    Hope to make it.

    May 22, 2013

  • A former member
    A former member

    Anyone driving from 90048 or 90036? Text me & if we go together I'll buy you dinner :) [masked]

    May 20, 2013

    • Paul R.

      Lindsay, if it's from 90048, no problem. 90036 won't work for me. I'd also prefer to leave by 6 at the latest; traffic is horrible that time of day. Let me know asap.

      May 20, 2013

    • A former member
      A former member

      Thank you for offering, but I just found a ride with a friend. I hope you enjoy the lecture!

      May 21, 2013

  • Sterling W.


    May 16, 2013

  • A former member
    A former member


    May 11, 2013

  • A former member
    A former member

    Too far away from Santa Monica

    April 20, 2013

  • malcolm

    Hope to make it.

    January 13, 2013

  • A former member
    A former member

    I can't wait for this lecture. It sounds absolutely fascinating!

    January 4, 2013

  • Alejandro L.

    Cant wait to come

    October 18, 2012

  • Scott R.

    Sounds amazing and why not plan ahead!

    October 3, 2012

35 went

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