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DIYbio Toronto Message Board › TORBUG: The Toronto Bioinformatics Users Group

TORBUG: The Toronto Bioinformatics Users Group

Eric B.
user 5529367
Group Organizer
Toronto, ON
Post #: 11­

"TorBUG (Toronto Bioinformatics Users Group) is an association of researchers, other professionals and students in the Greater Toronto Area who have an interest in the field of bioinformatics.

TorBUG meets on the last Wednesday of every month from September through April, except holidays. Research presentations by bioinformatics leaders, students and industry representatives are followed by networking over pizza and refreshments.

Meetings are held in the Red Room at the Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street at 4:00 pm and are free and open to all."

It was mentioned at our Study Group and I thought it looked super cool.
user 10735347
Toronto, ON
Post #: 10
The first TORBUG meeting of the academic year happens tomorrow:­

This one is about crunching the chemical features of a few thousand molecules to figure out what will (probably) interact with what, with the goal of predicting side effects. Papers here:



"Cyclobenzaprine caught our attention because even its mechanism of action target
for muscle relaxation has not been characterized, and its association with the off-target
discovered here, the H1 receptor (IC50 20 nM), precedes the identification of its primary
target. The central nervous system H1 receptor is strongly associated with somnolence,
consistent with the drug’s [side effects], and supported by its pharmacokinetics."
user 10735347
Toronto, ON
Post #: 11
And by "tomorrow" I mean "Wednesday".
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