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Fw: New MAF Golden Study - FYI

From: shirlee t.
Sent on: Monday, August 22, 2011 1:13 PM
----- Forwarded Message -----
From: shirlee thomas <[address removed]>
To: NGRR Group <[address removed]>; meetup <[address removed]>; Kristine Wallace <[address removed]>
Sent: Monday, August 22,[masked]:23 PM
Subject: New MAF Golden Study - FYI

Please read the info below.  This is why we need to get involved and help support Morris and the K9 Cancer Walks.  Please remember to register for the Los Gatos Walk on October 9th and join the Golden Retrievers To The Rescue Team.

MAGDIC Study - Making Advanced Discovery In Golden Cancers
Golden retrievers have been one of the most popular breeds in America for decades, but unfortunately these dogs also have one of the highest incidences of cancer. Hemangiosarcoma and lymphoma account for more than 30 percent of the deaths in this breed. Although breed susceptibility to cancer was first reported 30 years ago, the relationship between inherited traits and susceptibility for these cancers is still not known. The Golden Retriever Foundation and Morris Animal Foundation are funding MADGiC (Making Advanced Discoveries in Golden Cancers), a study that aims to discover and characterize heritable and somatic cancer mutations in golden retrievers. The three-year, $1 million project will examine heritable (genetic) traits that contribute to risk and progression of hemangiosarcoma and lymphoma in golden retrievers. The long-term goal is to understand what causes these diseases. Because both cancers occur with such high frequency, reducing their incidence (while retaining the positive phenotypes of the breed) will be a complex task, but the development of reliable genetic tests would allow breeders to build programs whereby high-risk combinations of factors could be avoided. In addition, effective strategies could be developed to control and treat hemangiosarcoma and lymphoma in golden retrievers and other dogs, and as importantly, what is learned from this research also may be applicable to develop effective prevention and treatment strategies for these diseases in people.
 Principal Investigator: Principal Investigator: Drs. Jaime F. Modiano, Matthew Breen and Kerstin Lindblad-Toh, Institutions: North Carolina State University, University of Minnesota and Uppsala University, Sweden
Co-sponsors: Golden Retriever Foundation & Morris Animal Foundation; American Spaniel Club Foundation; Flat-Coated Retriever Foundation; Portuguese Water Dog Foundation
 Study ID: D10CA-501

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