• Computer Modeling in Biology

    Baltimore Under Ground Science Space

    In biomedical experiments, we rely on data to gain insight about a system. This workshop series will focus on building and using computational models. We will use the R programming language to analyze sample data from biological experiments. Specifically, we will work with deterministic models, in which a system of equations is used to represent a biological process. Examples of these processes would be the body's response to pharmaceutical drugs, the time that a drug lasts in the body, and determining the proper dosage. We will employ computational techniques, such as parameter optimization and sensitivity analysis, to improve our models and gain information from them. We will also discuss applications of computational models in tissue engineering and drug development. No previous coding experience is needed! We welcome beginners and will make sure to help you learn how to perform all of the analyses! This is a 3-day class (3 consecutive Saturdays starting on March 2nd). Signup for the class at: https://modelingbiology.eventbrite.com Scholarships are available for all courses: Signup at https://goo.gl/forms/Rj2eVApZR4N75bnh2

  • Biodiversity of the Chesapeake Bay

    Baltimore Under Ground Science Space

    Join us for a panel discussion on the biodiversity of the Chesapeake Bay. We'll learn about how the health of the Baltimore Inner Harbor estuary impacts the Chesapeake Bay ecosystem. Our experts will discuss their research, and we'll hear about local oyster restoration initiatives. The panelists include: Eric Schott, Ph.D., Associate Research Professor, University of Maryland Center for Environmental Science at the Institute of Marine and Environmental Technology Carmera Thomas, Baltimore Program Manager, Chesapeake Bay Foundation Tiffany Kim, Program Manager, Healthy Harbor Initiative at Waterfront Partnership RSVP at: https://www.eventbrite.com/e/biodiversity-of-the-chesapeake-bay-tickets-54033110488

  • Evolution in Action: Lord of the Flies

    Baltimore Under Ground Science Space

    This class takes place over two days (Sat Jan 19th and Sat Feb 2nd). Please plan to attend both dates. But, you only need to sign up For the Jan 19th date and you will be enrolled for both dates. Are human beings still evolving? You bet they are! In this class we’ll learn all about natural selection. How does it work? Why is it important? How is it still occurring today? We’ll use one of scientists’ favorite model organisms, fruit flies, to explore how natural selection works, how it makes some organisms more likely to survive and reproduce, and how it leads to evolution. We will also discuss how humans are interfering in and influencing this process through the use (or abuse!) of artificial selection and gene drives to change the natural world. No lab experience necessary.

  • Lab Skills Night: Plasmid DNA Isolation

    Baltimore Under Ground Science Space

    Lab Skill Nights at BUGSS! Take 2 hours to learn an hands-on lab technique! To sign up for this same class on Jan 31st, please go to https://plasmidskills2.eventbrite.com To help work around busy schedules, two nights a month we will offer a hands-on learning experience of a specific technique. This month we will be teaching Pipette skills and Plasmid DNA Isolation. -For those that have not yet picked up a pipette it takes a bit getting used to. We will go over several proper pipetting techniques and tips to make sure you feel comfortable and confident. Soon enough this well-known molecular biology tool will be one of your favorites. - Want to cut, paste, and manipulate DNA? In order to work with specific DNA sequences, molecular biologists often take advantage of a bacterial component called plasmid DNA. These are small circular double-stranded pieces of DNA that are separate from the chromosomal DNA of the bacteria. Bacteria often use these plasmids to transfer genes that sometimes can benefit survival, such as antibiotic resistance. Molecular biologists use this system to put specific genes and DNA sequences into plasmids for expression and manipulation. This will be an immersive hands-on class so be prepared to attend the full 2 hours and listen carefully. Additional material will be available to help understand concepts and basic biology of this technique and applications.

  • Winter Open House

    Baltimore Under Ground Science Space

    Come visit the most creative science space in Baltimore. Check out the space, learn about what we do, meet our members and volunteers, get an overview of our upcoming courses and events, and find out how you can become involved. And, since it's the holiday season, you can make a momento to take away with you- your very own Christmas ornament full of bioluminescent dinoflagellates! Give your Christmas tree a beautiful blue glow! We'll also have our ever-popular Agar Art. Use fluorescent bacteria to create your own living art work by "painting" on petri dishes. Unfortunately, these can't leave the lab, but we'll send you a beautiful picture of your glowing art!

  • To Start Up or Not to Start Up? First Step: Customer Discovery

    Baltimore Under Ground Science Space

    Let us know you are attending via Eventbrite: https://startuphowto.eventbrite.com This is our final installment of our entrepreneur series in partnership with Harbor Launch of IMET! Tom Starr of Chesapeake Visions helps researchers, entrepreneurs, and investors with market research, customer discovery, commercialization planning, and Go-to-Market strategy. This will be an interactive workshop, led by Tom Starr, Founder & Principal at Chesapeake Visions, consisting of an informational briefing on market research & customer discovery and why its vital to the success of any new venture, discussion of best practices, and short breakout sessions for attendees to apply concepts learned to their own ideas.

  • Fireside Chat with Two Biotech Entrepreneurs

    Baltimore Under Ground Science Space

    FREE TICKETS HERE: https://firesideatbugss.eventbrite.com Fireside Chat with Two Biotech Entrepreneurs Join us for a moderated fireside chat with: Andrea Pais, Founder & CEO of Novel Microdevices Kelvin Liu, Founder & CEO of Circulomics, Inc. Thinking about starting or just started a biology-based venture? It can be very exciting -- and challenging! Learn from two Founders & CEOs of Baltimore-based biotech companies. Andrea Pais is Founder & CEO of Novel Microdevices. Founded in 2014, her company is is developing faster, more robust tests for infectious disease. They have performed field tests and recently received SBIR grant funding from the NIH. Andrea and her team are no stranger to BUGSS, which provided vital resources before the company was able to establish their own labs at Harbor Launch. Kelvin Liu is Founder & CEO of Circulomics. Founded in 2009, his company develops platforms for nucleic acid sample preparation, microRNA profiling, and single molecule analysis. They have received over $8M in grant funding from the NIH and recently launched their first beta kits for better DNA extraction. These Founders have seen success, continue to navigate challenges, and are sharing their story to hopefully inspire others who are on this path or thinking of starting down it.

  • What the fish? A DNA investigation into the fish we eat

    Baltimore Under Ground Science Space

    GET YOUR TICKETS HERE: https://fishatbugss.eventbrite.com CLASS: What the fish? A DNA investigation of the fish we eat WHEN: Please note this is a 2 session class (2 Saturdays, Sept 22nd and Sept 29th) please plan to attend both days,10am-2pm WHAT: You may be curious about the fish you purchase at your grocery store or local market. Is it really what they say it is? Test it for yourself in our lab and learn the process of DNA isolation, PCR, gel electrophoresis, and DNA barcoding and sequencing! If interested, we can assign digital badges through Credly. Badges that will be awarded to class participants that demonstrate understanding and basic skills. PLEASE let Sarah Laun [masked] know you would like to receive digital badges before the class! WHO: Class will be appropriate for adults, and high school students WHERE: Baltimore UnderGround Science Space (BUGSS) 101 N. Haven St suite 105 (King Cork and Seal Building) COST: Please be prepared to attend the entire time. Costs (not including online processing fees) are $140 for non-members. DIY Community BUGSS members get 60% of classes. 60% Discounts for our awesome BUGSS members! Not a BUGSS member yet? Join our community of citizen scientists, thinkers, and tinkerers and get mega awesome benefits (also gain infinite cool points!) inquire with [masked] or learn more here: http://www.bugssonline.org/payment.html REGISTRATION CLOSES 1 WEEK BEFORE CLASS! Please sign up by then! REFUNDS: Thank you for taking a class at BUGSS. The fees we charge help support BUGSS activities at making biotechnology accessible and provide assistance to those who can't afford the full tuition. Therefore we want you to be aware of our cancellation policy. If BUGSS cancels a course you will be refunded the entire course fee. If you have to cancel, cancellations made prior to 2 weeks before the course start date will be issued a full refund minus a $15.00 service fee. Cancellations within two weeks of the course start date will be granted a credit for future classes at BUGSS.

  • BUGSS Volunteer Orientation Day!

    Baltimore Under Ground Science Space

    Let us know you are joining us! https://volunteeratbugss.eventbrite.com Volunteer Orientation Day! Are you looking to volunteer at BUGSS to enhance your lab experience, science communication, teaching skills, or just have a super- cool place to hang out with fun people? Join us September 20th at 7pm for our Volunteer Orientation Day!! Get to know our volunteers and introduce ourselves Lab safety, security, and bio-ethics Tour of the lab and space with Q and A Review positions and times available – assist with signing up on our website BUGSS is a lab FOR the COMMUNITY! We need the community to be a strong and present part of BUGSS so we value and appreciate our volunteers! Thank you for your interest and please pass along the word! Let’s make Baltimore a community of science, together!

  • Lab Skills Nights! - RNA isolation (what is a transcriptome?)

    Baltimore Under Ground Science Space

    Non-members $30, members $12 o help work around busy schedules, two nights a month we will offer a hands-on learning experience of a specific technique. The month of September we will be teaching RNA isolation! -For those that have not yet picked up a pipette it takes a bit getting used to. We will go over several proper pipetting techniques and tips to make sure you feel comfortable and confident. Soon enough this well-known molecular biology tool will be one of your favorites. RNA isolation: It's an RNA world! RNA might have been the first molecule of "life" and we are going to spend some time learning how to isolate it from cells. Also learn about what the "transcriptome" is all about. Digital Badges can be requested to be earned with each session via Credly. Please mention during course if you are interested! This will be an immersive hands-on class so be prepared to attend the full 2 hours and listen carefully. Additional material will be available to help understand concepts and basic biology of this technique and applications. Non-members $30, members $12 Not a BUGSS member yet? Join our community of citizen scientists, thinkers, and tinkerers and get mega awesome benefits (also gain infinite cool points!) inquire with [masked]!