This talk will focus on the groups foundational methods for genetic circuit design, including the quantification of metabolic burden, as well as the automatic control of synthetic gene circuits. The following questions will be posed:
• How can we design taking into account shared resources?
• How can we improve the dynamic performance of synbio systems?
• How can we use cells to control their surrounding environment?
Dr Guy-Bart Stan is a Professor in Engineering Design for Synthetic Biology and the head of the "Control Engineering Synthetic Biology" group at the Department of Bioengineering at Imperial College London. The group are working on mathematical aspects of modelling, analysis and control in biological systems and their applications in synthetic biology. A particular interest is the study of in vivo implementation of bio-molecular feedback control mechanisms for the robust and efficient automatic control of gene regulation and metabolic pathways in natural and synthetic systems. The envisioned target applications for the novel designs include cell-based medicine, more efficient biosynthesis, and to scale-up synthetic biology and biotechnology. For more information about the work taking place visit their website: http://www.bg.ic.ac.uk/research/g.stan/group.
Event details: https://www.facebook.com/events/1507686329540820/