Regenerative medicine for aging: are we reaching the knee of the exponential curve?
*** Note change of room, to room B04, to accommodate a larger audience ***
Aubrey de Grey writes:
In this talk I will explain why therapies that can add 30 healthy years to the remaining lifespan of typical 60-year-olds may well arrive within the next few decades.
It might seem premature to be discussing the medical control of human aging when so little progress has yet been made in even postponing it. However, two facts undermine this assessment. The first is that aging happens throughout our lives but only causes ill-health after middle age: we can postpone that ill-health, by molecular and cellular repair, even without knowing how to prevent aging completely. The second is that regenerative medicine is now advancing from a futuristic twinkle in a few visionaries' eyes to a realistic strategy for addressing numerous medical conditions.
The talk will have an emphasis on recent progress both in SENS Foundation's own work and elsewhere.
About Aubrey de Grey:
Dr. Aubrey de Grey (http://www.sens.org/users/aubrey-de-grey) is a biomedical gerontologist based in Cambridge, UK and Mountain View, California, USA, and is the Chief Science Officer of SENS Foundation (http://www.sens.org/), a California-based 501(c)(3) charity dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging.
Dr. de Grey received his BA and Ph.D. from the University of Cambridge in 1985 and 2000 respectively. His original field was computer science, and he did research in the private sector for six years in the area of software verification before switching to biogerontology in the mid-1990s. His research interests encompass the characterisation of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging and the design of interventions to repair and/or obviate that damage. He has developed a possibly comprehensive plan for such repair, termed Strategies for Engineered Negligible Senescence (SENS), which breaks aging down into seven major classes of damage and identifies detailed approaches to addressing each one.
A key aspect of SENS is that it can potentially extend healthy lifespan without limit, even though these repair processes will probably never be perfect, as the repair only needs to approach perfection rapidly enough to keep the overall level of damage below pathogenic levels. Dr. de Grey has termed this required rate of improvement of repair therapies “longevity escape velocity”.
Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organisations.
2pm-4pm, Sunday 2nd September
Venue: Room B04, Birkbeck College (http://www.bbk.ac.uk/maps), Torrington Square WC1E 7HX, London.
Room B04 is on the basement level in the main Birkbeck College building, in Torrington Square (which is a pedestrian-only square). Torrington Square is about 10 minutes walk from either Russell Square or Goodge St tube stations.
Coffee and other light refreshments can be purchased from the Costa Coffee shop in the reception area of the building, either ahead of or after the meeting.
The event will be followed by a chance to continue the discussion in a nearby pub - The Marlborough Arms (http://www.taylor-walker.co.uk/pub-food/marlborough-arms-bloomsbury/pid-C7440), 36 Torrington Place, London WC1E 7HJ
The meeting is free to attend - no charge.