I'm having loads of fun with 5e and I'd like to share my excitement with others by running a Sci-Fantasy campaign in my Urutsk setting. The blog address is http://thegrandtapestry.blogspot.com/ and should give a sense of what is going on, and the scope of work I've invested in the world.
Medieval level technology is the norm for the vast majority of the world's population, and most don't realise that grounded starships and blaster wielding cyborgs are part of the setting. Magic is dynamic, but thought to be well under the control of Humanity, and integrated into technology. Humanoids, Monstrous Beings, and worse lurk in the wilds, and there is much loot to be plundered in ruins covered in the green tangle of wilderness.