Discuss: "The Transhumanist Wager" by Zoltan Istvan

Is this book a Call to Arms for rationalists in the 21st Century or just too damned radical? http://en.wikipedia.org/wiki/The_Transhumanist_Wager
http://www.amazon.com.au/The-Transhumanist-Wager-Zoltan-Istvan-ebook/dp/B00AQQSY60/ref=sr_1_1?ie=UTF8&qid=1407559169&sr=8-1&keywords=zoltan+istvan

I thought it was the best thing I have read in decades!

We have not had a face-to-face Meetup for a long time and I will be out of Sydney for a while soon so I thought we could catch up and discuss this and also anything else of interest.