Why R? 012 Neural Networks for Modelling Molecular Interactions w/ Tensorflow

Name: Why R? 012 Neural Networks for Modelling Molecular Interactions w/ Tensorflow
Start: 2020-06-25T20:00:00+02:00
End: 2020-06-25T21:00:00+02:00

Hosted By

MarcinKosinski

Why R? 012 Neural Networks for Modelling Molecular Interactions w/ Tensorflow

Szczegóły

Financed by the 'Perfect Science' program of the Polish Minister of Science and Higher Education

stream: https://youtu.be/ApGL2gBPHY4
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join YouTube http://whyr.pl/webinars/
format: one 45 minutes long stream + 10 minutes for Q&A
comments: ask questions on YouTube live chat
speaker: Leon Eyrich Jessen
title: In Silico Immunology: Neural Networks for Modelling Molecular Interactions using Tensorflow via Keras in R

Biogram

Leon Eyrich Jessen is an assistant professor of bioinformatics at department of Health Technology at Technical University of Denmark (DTU). He obtained his PhD in bioinformatics from the Center for Biological Sequences Analysis at DTU in 2014 after which he held two postdoctoral positions in clinical genetics. Hereafter, he returned to the newly formed Department of Health Technology to continue his research in the Immunoinformatics and Machine Learning Group at section for bioinformatics. Throughout his career, his research focus has been on connecting genotype to phenotype in an immunological context.

Abstract:

Understanding what constitutes an immune target is pivotal in vaccinology. With the advent of COVID-19 this has only become more evident. While computer-based predictions cannot replace traditional experimental validation in the laboratory, it can serve as an important tool to drastically reduce the target search space and increase understanding. In this webinar, I will demonstrate how we can model immune targets using artificial neural networks (ANNs) in R. ANNs constitute the basic building block of Deep Learning. Moreover, I will use the binding of peptides to the Major Histocompatibility Complex class I (MHCI) as a study case. pMHC formation is a precursor for activation of cytotoxic T-lymphocytes, which in turn is the primary system for ridding the body of viral infections. The webinar assumes no prior knowledge and will be followed by a Q&A.