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Dr. Elissa Hobert will present a paper about modified RNA (modRNA) and its applications for treating disease. She is a scientist at Moderna Therapeutics, a company that develops new amazing treatments based on this technology.

The paper that we are going to discuss:
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
http://www.nature.com/nbt/journal/v31/n10/full/nbt.2682.html

The agenda for the journal club:
- Short overview of the paper to understand the scope of this work.
- Go over the paper figure by figure. So everyone understand what exactly was done and how it was done.
- Free form discussion.

Previous reading of the paper is not required but much advised. It will help you to follow along. As well some prior knowledge of basic biological concepts will be very useful, especially the central dogma of DNA -> RNA -> Proteins.

Location:
We are changing the location of our Journal Club to our lab space in Somerville. So for those of you who never visited BosLab, this is another chance to see it!