Past Meetup

Journal Club: Phage-assisted continuous evolution (PACE)

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Details

Dr. Ben Thuronyi will be presenting a paper about Phage-assisted continuous evolution (PACE). Ben is a postdoctoral fellow at David R. Liu group at Harvard, where the actual technology was co-developed.

The paper that we are going to discuss:
A system for the continuous directed evolution of biomolecules
http://evolve.harvard.edu/71-PACE.pdf

The agenda for the journal club:
- Short overview of the paper to understand the scope of this work.
- Go over the paper figure by figure. So everyone understand what exactly was done and how it was done.
- Free form discussion.

Previous reading of the paper is not required but much advised. It will help you to follow along. As well some prior knowledge of basic biological concepts will be very useful, especially the central dogma of DNA -> RNA -> Proteins.