PDX Science & Nature Book Club

# Replaceable You: Adventures in Human Anatomy

### Mary Roach

Goodreads Choice Award
Nominee for Readers' Favorite Nonfiction (2025)
From the New York Times best-selling author of Stiff and Fuzz, a rollicking exploration of the quest to re-create the impossible complexities of human anatomy.

Free epub copy here.

The body is the most complex machine in the world, and the only one for which you cannot get a replacement part from the manufacturer. For centuries, medicine has reached for what’s available—sculpting noses from brass, borrowing skin from frogs and hearts from pigs, crafting eye parts from jet canopies and breasts from petroleum by-products. Today we’re attempting to grow body parts from scratch using stem cells and 3D printers. How are we doing? Are we there yet?

In Replaceable You, Mary Roach explores the remarkable advances and difficult questions prompted by the human body’s failings. When and how does a person decide they’d be better off with a prosthetic than their existing limb? Can a donated heart be made to beat forever? Can an intestine provide a workable substitute for a vagina?

Roach dives in with her characteristic verve and infectious wit. Her travels take her to the OR at a legendary burn unit in Boston, a “superclean” xeno-pigsty in China, and a stem cell “hair nursery” in the San Diego tech hub. She talks with researchers and surgeons, amputees and ostomates, printers of kidneys and designers of wearable organs. She spends time in a working iron lung from the 1950s, stays up all night with recovery techs as they disassemble and reassemble a tissue donor, and travels across Mongolia with the cataract surgeons of Orbis International.

Irrepressible and accessible, Replaceable You immerses readers in the wondrous, improbable, and surreal quest to build a new you.

### Simon Parkin

From the award-winning author of The Island of Extraordinary Captives, the riveting, untold true story of the botanists at the world’s first seed bank who were faced with an impossible choice during the Second World War’s Siege of eat the seeds to stave off starvation, or protect their life’s work to potentially end world hunger?

Free epub copy here.

In the summer of 1941, German troops surrounded Leningrad with a plan to besiege the Russian city and starve its citizens into submission. So began the longest blockade in recorded history. By conservative estimates, it would claim the lives of three-quarters of a million people—four times the number killed in the atomic bombings of Nagasaki and Hiroshima combined. Most died by starvation. At that time, the world’s largest collection of seeds and plants were stored in a converted palace building in the city center. Hand-collected during the previous two decades under the leadership of the world-famous explorer Nikolai Vavilov, the Plant Institute represented the greatest living library of plant matter ever assembled, more than a quarter of a million seeds from every continent. But as the siege wore on, attempts to evacuate this priceless collection failed. Trapped in the city with dwindling supplies, the botanists faced a terrible should they distribute the seeds to the city’s starving population, or preserve them in the hopes that future scientists might use them to breed crops and prevent future famine? Drawing from previously unseen primary sources, The Forbidden Garden tells for the first time the story of the botanists who remained at the Plant Institute during the darkest days of the blockade, many of whom sacrificed their lives in service to their mission. As climate change, wars, and supply chain issues impact food security in today’s times, this fascinating story remains as relevant and urgent as ever.