Skip to content

BACE Technology Showcase: biomodal and 6-DNA base sequencing

Photo of Monika Maleszewska
Hosted By
Monika M.
BACE Technology Showcase: biomodal and 6-DNA base sequencing

Details

Did you ever wish you could sequence unmethylated and methylated DNA in the same run, getting double the information from each sample and experiment? In the next BACE Technology Showcase we will explore the new technology from biomodal, that allows you to sequence all 6 bases of DNA in one go.

Join us for an hour of learning and exploration, with our special guest, Tom Charlesworth, Ph.D., Director of Market Strategy and Corporate Development at biomodal.

Presentation Title:
Using simultaneous genetic and epigenetic information from the 6-base genome to predict gene expression, chromatin accessibility and enhancer status
Description:
Using a new sequencing technology, duet evoC, we are able to deconvolute A,T,C,G, 5-mC and 5-hmC simultaneously from the same DNA molecule in a single experiment. Using a mouse embryonic stem cell-line, ES-E14TG2A, we mapped for the first time a comprehensive reading of the genome and epigenome at high depth. We show how this 6-base genome combined with novel, memory efficient, software tools can be used to predict gene expression, chromatin accessibility and the status of gene regulatory elements.

Please register via biomodal's webpage here: https://biomodal.com/events/bay-area-chromatin-and-epigenomics-bace-virtual-lunch-learn/

Photo of Bay Area Chromatin and Epigenomics Group group
Bay Area Chromatin and Epigenomics Group
See more events