Computational Biology

15. Vers La Libération /542 end p. 600. 58 pages.

🎭 DMV Mystery & Social Game Night! 🍦 Looking for a fun, social way to spend your Saturday? Join us for a mix of Secret Hitler, Mafia, and murder mystery games — no experience needed, just bring your sense of humor! 🗓️ Every 3rd Saturday @ 4 PM 📍 Meridian at Eisenhower 🍨 Snacks, ice cream, and good vibes provided 👥 Hosts: Terry (626) 679-5001 & Nishant (914) 473-0481 Come solo or with friends — we’ll make sure you feel welcome and included. 😄 Fun games • New friends • Great energy

Francis Hutcheson (1694-1746) was a pivotal early figure of the Scottish Enlightenment, a movement which strongly embraced empiricism and concentrated on the study of human nature and the relationship of individuals and society. Born in Ireland to a line of Scottish Presbyterian ministers, Hutcheson was educated by dissenting Irish Presbyterians in Ulster before matriculating at the University of Glasgow, where he studied philosophy and theology. In 1719 he was licensed to preach in Ireland, but rather than adopting the more traditional views of his forefathers, he gravitated toward the tolerant and liberal “New Light” Presbyterianism. Instead of further pursuing the ministry for which he had trained, he put his efforts into founding a dissenting academy in Dublin—a successful venture that occupied him for the next ten years. While teaching in Dublin, he moved in intellectual circles, and it was there that he wrote the four early treatises—collected into two books, the *Inquiry* of 1725 and the *Essay* of 1728—that quickly established his reputation as a philosopher. On being appointed chair of moral philosophy at his alma mater, he left Ireland for Glasgow in 1729. Contemporaries described Hutcheson as a popular and animated professor—the first at Glasgow to deliver lectures in English rather than exclusively in Latin. His most famous student was Adam Smith (enrolled 1737-40). Hutcheson's influence on Scottish thinkers was considerable. With his emphasis on the primacy of feeling over reason in our moral perceptions, he inspired David Hume’s moral sentimentalism. His analysis of natural rights and property in the *Inquiry* (Treat. II Sect. VII) as well as in his later works directly influenced Smith. The Scottish school of common sense realism derived partly from Hutcheson's explication of moral sense theory. His influence also made its way to colonial America, where his works were included in college curricula beginning in the mid-1700s. John Adams and other signers of the Declaration of Independence are known to have read Hutcheson. In the *Inquiry*, he takes up Locke’s epistemology of sense perception and broadens it into a theory of the “internal senses”—faculties of perception as powerful as the commonly designated five external senses. Elaborating Lord Shaftesbury’s notion of a “moral sense” and the earl's analogy between beauty and virtue, Hutcheson divided his *Inquiry* into a discussion of the sense of beauty and of the paramount moral sense—both being internal senses which operate without depending on mediation by the will or reason. Like Shaftesbury and the philosopher Richard Cumberland, Hutcheson held a strong distaste for the Hobbesian worldview. In the vein of the former two, he promoted a vision of humans as naturally benevolent and innately interested in the welfare of others, maintaining that others’ good brings us no less pleasure than our own good. Notably, he also sowed the seeds of utilitarian thought with his phrase “the greatest happiness for the greatest numbers” (Treat. II Sect. III). **Main Reading** The reading below is available at the Online Library of Liberty: * The [Inquiry](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004), comprising the first two of Hutcheson's four early treatises (we are reading the 1726, or 2nd edition, of the book): read the [Preface](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_head_019) and Treat. I: Sections [I](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_051), [II](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_071), [III](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_088) (Art. [IV](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_101) is optional), ([V](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_109) is optional), [VI](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_137), [VII](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_158), [VIII](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_165); and Treat. II: [Intro](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_head_032) and Sect. [I](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_181), [II](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_205), [III](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_228) (Art. XI, XII until “Intention, foresight” optional), [IV](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_258), [V](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_275), [VI](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_296), and especially [VII](https://oll.libertyfund.org/titles/leidhold-an-inquiry-into-the-original-of-our-ideas-of-beauty-and-virtue-1726-2004#lf1458_label_324). * Hutcheson's lecture upon his appointment at Glasgow, “[On the Natural Sociability of Mankind](https://oll.libertyfund.org/titles/hutcheson-logic-metaphysics-and-the-natural-sociability-of-mankind#lfHutcheson_head_238)." The first 3 paragraphs, until footnote 10, are optional. * The beginning of the fourth treatise [Illustrations](https://oll.libertyfund.org/titles/garrett-an-essay-on-the-nature-and-conduct-of-the-passions-and-affections-1742-2002#lf0150_label_230), Sect. [I](https://oll.libertyfund.org/titles/garrett-an-essay-on-the-nature-and-conduct-of-the-passions-and-affections-1742-2002#lf0150_head_019), and Sect. [IV](https://oll.libertyfund.org/titles/garrett-an-essay-on-the-nature-and-conduct-of-the-passions-and-affections-1742-2002#lf0150_label_296). Note that the ebook page on OLL can take a few moments to load. **Secondary resources** [IEP - Hutcheson](https://iep.utm.edu/hutcheso/) [SEP - Hutcheson](https://plato.stanford.edu/entries/hutcheson/) Liberty Fund: Editor’s [Intro to Inquiry](https://oll.libertyfund.org/pages/hutcheson-on-liberty-and-happiness). [SEP - Scottish 18th C. Philosophy](https://plato.stanford.edu/entries/scottish-18th/) [Wiki - Scottish Enlightenment](https://en.wikipedia.org/wiki/Scottish_Enlightenment) [Hutcheson and private property](https://www.adamsmithworks.org/documents/matson-hutcheson-property-virtue-march-2022) Routledge: [1](https://www.rep.routledge.com/articles/biographical/hutcheson-francis-1694-1746/v-1/sections/life-and-works-43333), [2](https://www.rep.routledge.com/articles/biographical/hutcheson-francis-1694-1746/v-1/sections/the-foundations-of-morality-and-the-moral-sense), [3](https://www.rep.routledge.com/articles/biographical/hutcheson-francis-1694-1746/v-1/sections/practical-ethics-and-influence)

We will be playing Moon Colony Bloodbath with up to 8 players. All experience levels welcome. Expect the game teach to start promptly within the first 10 minutes. In Moon Colony Bloodbath players develop cities on the moon! Moon Colony Bloodbath is an engine-building, engine-losing tableau game, with a shared deck the players build that makes things happen, many of them bad things that kill people in your moon colony, but some positive, and some that let you build up. The game lasts until one player's moon colony has no people remaining, or until the players reach the bottom of the event deck. At that point, the player with the most survivors wins. Find [here](https://www.youtube.com/watch?v=JZgKbxvav00&pp=ygUhaG93IHRvIHBsYXkgbW9vbiBjb2xvbnkgYmxvb2RiYXRo) a how to play video on youtube. Find [here](https://www.riograndegames.com/wp-content/uploads/2024/07/MCB.pdf) the rulebook. Note: Please remember to update your RSVP if you can not attend the event. By updating your RSVP when you can't make it other players on the waitlist will have a chance to attend. No-shows may make it harder to attend future meetups. Also, all library rules apply to this meetup event. Mainly that no food is allowed in the library. Covered drinks are allowed.

[Book Your Classes by Clicking This Link! ](https://crowndancestudio.com/group-classes/) Take a deep dive into the world of Latin rhythm with our **Level 2 Bachata workshop from 1:30 PM to 3:00 PM**. This 90-minute intensive is crafted for dancers who have moved past the basics and are ready to refine their body mechanics, intricate footwork, and partner connection. **For $25,** you’ll receive focused, high-value instruction that bridges the gap between foundational steps and social dance mastery, ensuring you leave the studio feeling confident and inspired

**This talk has completely sold out in advance and no additional tickets will be sold at the door. A repeat of the talk at Penn Social in DC on Monday, May 18 still has tickets available.** [Profs and Pints Northern Virginia](https://www.profsandpints.com/washingtondc) presents: **“How AI Alters Thinking,”** on dealing with artificial intelligence’s capacity to change and undermine our thought processes, with Eli Alshanetsky, assistant professor of philosophy at Temple University, principal investigator at its Cognitive Integrity Lab, and author of an upcoming book on AI and freedom of thought. [Advance tickets: $13.50 plus sales tax and processing fees. Available at [https://events.ticketleap.com/tickets/profsandpints/nv-how-ai-alters](https://events.ticketleap.com/tickets/profsandpints/nv-how-ai-alters) .] Doctors who give bad advice can be sued for malpractice. Teachers belong to a profession with set standards. When artificial intelligence guides you, however, that guidance comes with a disclaimer: Use at your own risk. Every day millions of people take that risk, and usually AI seems genuinely helpful. But even if AI gives us good answers, might its use over time do bad things to how we think? Explore the relationship between AI and our own minds with Eli Alshanetsky, whose Cognitive Integrity Lab studies how artificial intelligence changes how we think, learn, and build trust. Author of *Articulating a Thought* and the upcoming book F*reedom of Thought in the Age of AI*, he’s on the cutting edge of efforts to answer AI-related questions such as: How can we tell when work is truly our own? How can technology support rather than replace authorship and reflection? What does trust mean when AI mediates our relationships with others and with our own thoughts? To set up his discussion of potential consequences of AI, he’ll describe how social media’s impact on society serves as a preview. Social media didn’t just give people what they wanted to click on, it actually changed what they regarded as click-worthy. It broke attention spans and fueled radicalization across millions of very different people. It left us with people who doom-scroll for hours, who can’t focus, who don’t know what to trust anymore. If you’d shown people this version of themselves ten years ago, would they have chosen it? Artificial intelligence is making a similar deal with us, but the stakes are higher. It isn’t chasing clicks. It’s optimized for giving you the most satisfying response to whatever is on your mind right now. The risk over time isn’t just that you’ll get lazy. More profoundly, even when you think hard, your sense of what counts as good thinking—as well as what sounds like you—will shift to match what AI has been feeding you. We’ll consider what kind of person this produces and whether this is someone we want to be or want children to become. Professor Alshanetsky will lay out a practical framework, which he calls “the interaction layer,” for using AI without letting it replace the thinking it’s supposed to support. He’ll also talk about what AI-related concerns should be the focus of parents and educators. (Doors: $17, or $15 with a student ID. Listed time is for doors. Talk starts 30 minutes later.) Image: Illustration by David S. Soriano / Creative Commons.

Come the whole time or if you just spend 30 minutes. All are welcome. You are welcome and encouraged to bring your own coloring supplies but, if you don't have any, I will have plenty and am happy to share! (coloring books, colored pencils, and markers). Part of the mission of this group is to provide us an opportunity to check out AND SUPPORT local businesses. So, please don't bring any outside food/drinks and, while purchasing something isn't at all a REQUIREMENT to participate in the event, I do strongly encourage you to try something from the vendor :) I look forward to seeing and meeting you there! ***\*\*DISCLAIMER*\*\*** Photos may be taken during the event to be shared here on Meetup so feel free to let me know if you'd like to be excluded from them.

Our next club meeting is on Sunday will start at 2:15, please join early. if you're coming in-person, parking is free and usually ample at the Community College on Sundays, and most of us park where the spaces are designated for staff and have never had a problem. 👉 Everyone is welcome to join our meeting, participate and practice. You'll get a chance to hear our club members speak and then have an opportunity to play the table topics game. **Agenda for the Meeting:** 1. Warm Up 2. Prepared Speeches (By club members) 3. Table Topics Game (Learn to think on your feet) 4. Feedback **Online - Join us via Zoom** https://us05web.zoom.us/j/86218205188 If you haven't used Zoom before, watch this short video on how to join our meeting - https://www.youtube.com/watch?time_continue=45&v=vFhAEoCF7jg **In-Person** **\- Join us at Montgomery Community College** Meet us at Science Building, room SC 152. The room is located on the ground floor. The exact building address is https://goo.gl/maps/ZEgQH7bKLvzdqtSQ9 For help, please text or call, 301-917-4202.

**Real connection with fellow Catholics who are eager to grow in Faith and friendship!** This 3 year--- 45min deep dive into the Catholic faith is a great way to spend your Sunday rest day. When you are ready to dig deeper and live the faith more fully this is an optimal opportunity. Talk yourself into this! You may start whenever and can come as often or as little as you desire. Coffee is served w/ small donation. It is taught by the priest and/or OCIA director at St Louis Parish who are ALL fabulous- faithful educators filled with theologically inspired knowledge. You can ask questions at the end, which I love. It is just a wonderful experience to grow. Afterwards if you wish, you can also find your way over to the Little Way Cafe Coffee shop across the parking lot to stay for more community time or read some of the excellent books that line the shelves throughout. If you are new to the community of Alexandria and want to meet like minded folks or a veteran of it, this is a special and unique opportunity and did I mention it is free? :) Hard to believe! Please join me every Sunday at 945 am.

**\*TO ATTEND GET TICKET At** [https://www.socialevents123.com/event-details.aspx?id=13397#tix](https://www.socialevents123.com/event-details.aspx?id=13397#tix) (Multiple Meetup groups are co-organizing so the RSVP's shown are just a very small portion attending. We'll have at least 20 registered.) Our last online Bingo Night Party was such a BIG hit, we're doing it again! Do you like to play BINGO or want to just do something different?! Then you will LOVE this event! Here is your opportunity to have some fun playing our Live "Bingo" game. You will also get to socialize and make other friends from the comfort of your home. Prizes included Amazon gift cards, free future events and more! This completely online event will be LIVE and you will be able to see and hear the other participants while playing. You will either need to print or draw out your bingo cards. We will email you with how to get it after registering. You can have more than 1 person on your team as long as they're from your house and use same device. Friends/family around the country can also play. They would just need to also register for a ticket. This event will be held on Zoom which you would access through your computer/webcam, or via your phone/tablet. On day of the event, you will get a secured Zoom link and link to print out Bingo cards. \*RSVPS ON HERE ARE NOT REFLECTIVE OF ACTUAL ATTENDANCE as this is a multi group event. Cost: $15-$20 depending on how early you register. **\*TO ATTEND GET TICKET AT -** [https://www.socialevents123.com/event-details.aspx?id=13397#tix](https://www.socialevents123.com/event-details.aspx?id=13397#tix)

We are going to talk about the books we read—any books, from any genre. Whether it’s fiction or nonfiction, classic literature or something modern, everyone is welcome to share their thoughts, impressions, and favorite passages. It’s a relaxed and friendly conversation where we can discover new ideas and enjoy each other’s perspectives.

MoCo Code and Coffee is an inclusive, informal, co-working session. We're community-led and community-run by devs, for devs. People of all skill levels are invited. Especially new devs! Bring a laptop, ideas, and we'll provide the coffee and snacks. **Here's how it works** At 2:30pm, everyone introduces themselves and briefly mention what brought them to Code & Coffee today (project, homework, networking, etc.) Round 1: 1. Your name 2. What you're working on 3. What you can help others with Round 2: * Job opportunities you're hiring for OR announce that you are looking for one. If none, that's cool. Round 3: * Community events you wanna plug. If none, that's cool too. **After the introduction circle, everything is self-organized!** 1. For the rest of the day, folks work on their projects, providing one another with help, and/or socialize. It's fully up to you. **Location** We will be at the cafeteria of the County Executive Office Building in Rockville. 101 Monroe Street, Rockville, MD 20850 The event will be held in a spacious cafeteria with plenty of tables and chairs. Light refreshments (coffee and tea) and snacks will be provided. **Parking** * Visitor Parking is available at the First Level of the Council Office Building Parking Garage. Entrance only from East Jefferson and Monroe Street intersection. More information is here: https://www.montgomerycountymd.gov/mcg/direction-to-eob.html * PLEASE NOTE: The garage referenced above is ACROSS THE STREET from the Executive Office Building. This is NOT the garage at the base of the Executive Office Building structure - that one is for employee and permit parking only. * If that garage is not available, there may be street parking available. The Rockville Town Square garages have up to 90 minutes of free parking are not too far away. Parking at the Rockville Metro station would be free on weekends. **Public transit** * Located near near the **Rockville** metro station (Red Line).

Customer identity resolution becomes increasingly complex as organizations scale across multiple systems, regions, and data formats. Traditional rule-based approaches often fail to keep up with data variability, require constant manual tuning, and struggle with real-time processing needs. This session presents a practical approach to building a scalable identity resolution pipeline using AWS services and modern AI techniques. The architecture combines data ingestion through Amazon S3 and AWS Glue, transformation pipelines using Spark on EMR, and machine learning models deployed via SageMaker for entity matching and standardization. Graph-based relationship modeling is implemented using Amazon Neptune to improve resolution accuracy by incorporating household and shared attribute context. We will walk through how machine learning models can be used for name and address normalization, how intelligent blocking strategies improve matching efficiency, and how feedback loops can be introduced to continuously improve accuracy. The session also highlights how serverless components such as AWS Lambda can be used for orchestration and real-time processing. **SPEAKER BIO** Mosaic Syed is a Senior Data Engineering and Cloud Solutions Architect with over 20 years of experience designing and delivering scalable, secure, and high-performance data solutions across global enterprise environments. https://www.linkedin.com/in/mosaic-basha-syed-92300856 **CALL FOR SPEAKERS** Learn more: [https://www.awscolumbus.com/get-involved/](https://www.awscolumbus.com/get-involved/) **THANK YOU** *VEEAM* for hosting our meetup! To learn more about *Veeam*, please visit their website: [https://www.veeam.com/](https://www.veeam.com/) **DIRECTIONS** 8800 Lyra Dr #450 · Columbus, OH go to 4th floor. **Want to sponsor the pizza and/or bar tab?** Please contact me if you would like to sponsor this meetup's pizza and/or bar tab: angelo@mandato.com

We will show how to build custom agents with Microsoft Agent Framework. Attendees will learn how to build and custom host agents when Microsoft Foundry is not a viable option.

**Important time note:** Please plan on arriving between 5:30 and 6:00 as the elevators lock after 6 and you'll need to message us and we'll need to come get you. The building address is 4450 Bridge Park The entrance is 6620 Mooney St, Suite 400 You will need to scan your ID at the door to get a visitor badge. **Abstract** TBD **YouTube Link** TBD

**Improving Office in Franklinton** Physical location: Improving Office 330 Rush Alley Suite #150 Columbus, OH 43215 Schedule: 6:00 p.m.: Socialize, eat, and drink. Improving will be providing pizza and beverages. 6:30 to 8:00 pm. Main meeting and presentation(s). Topic: This month John Lairson will share a notebook describing the Alpaca (Paper) Trading API and discuss different algorithms for evaluating stock trades. We meet on the last Monday of each Month. Presentations are given by members and friends of this group. If you would like to do a presentation (small or large) on a python topic, please contact Central OH Python at centralohpython@gmail.com

We connect you with up to 30 Men or Women tennis partners close to your PLAYING REGION and skill level. This program is less competitive, no champions crowned, no league standings just dedicated tennis partners who want to meet up with you on the courts. Players will meet up to play a tennis match or just to hit around. Just go through the [Join Page](https://www.tenniscolumbus.com/partner-program) to enter this program. [https://www.tenniscolumbus.com/partner-program](https://www.tenniscolumbus.com/partner-program)

Join the Columbus AI community for our quarterly gathering — a casual, community-focused evening where everyone has a chance to share, learn, and connect. These open mic–style events give anyone in the community up to **5 minutes** to present a project, share a tool, pose a question, or offer a perspective on the evolving AI space. No slides required — just a welcoming space to exchange ideas and keep the local AI conversation moving. If you’d like to take the stage, message \*\*Chris (the organizer)\*\*with a **title and short description** of what you’d like to share. Whether you’re deep in the field or just getting curious, come connect with others building and exploring AI in Columbus. Sponsored by [Transform Labs](https://www.linkedin.com/company/transformlabs/) Sign up also accessible via [Transform Labs Luma](https://luma.com/transformlabshq)

**Latest Dojo Location!** **Knotty Pine Brewing** 1765 W 3rd Ave, Columbus, OH 43212 We're going to try a new dojo location for a few weeks and see how it works Dojos are informal Python group study sessions where everyone interested in Python gathers to learn about Python, help others with Python, or just hang out. Everyone is welcome from Python beginners to experts. Bringing a laptop is encouraged (we'll have extension cords and power strips). If there's something you want to learn leave a comment on this invite so we can plan ahead. We're looking for speakers for our Monthly Meetups! Fill out the form if you are interested in presenting to the Python Community. https://forms.gle/ehSfUAC2WgR34Crq9