"A Confederacy of Dunces" by John Kennedy Toole

Here is Ignatius Reilly: slob extraordinary, a mad Oliver Hardy, a fat Don Quixote, a perverse Thomas Aquinas rolled into one, who is in violent revolt against the entire modern age, lying in his flannel nightshirt in a back bedroom on Constantinople Street in New Orleans, who between gigantic seizures of flatulence and eructations is filling dozens of Big Chief tablets with invective.

His mother thinks he needs to go to work. He does, in a succession of jobs. Each job rapidly escalates into a lunatic adventure, a full-blown disaster; yet each has, like Don Quixote's, its own eerie logic.
His girlfriend, Myrna Minkoff of the Bronx, thinks he needs sex.

Ignatius is an intellectual, ideologue, deadbeat, goof-off, glutton, who should repel the reader with his gargantuan bloats, his thunderous contempt, and one-man war against everybody: Freud, homosexuals, heterosexuals, Protestants, and the assorted excesses of modern times.

A tragicomedy, set in New Orleans. - Goodreads

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