Python Tooling ecosystem in 2025

This list of tools in the python ecosystem is large. Just package management includes: poetry, pyenv, pip, flit, hatch, pdm, pipenv, etc.
Then there is also black, flake8, pylint, ruff, uv, mypy, pyre, pyright.
What is the state of the python ecosystem tooling these days? What tools should you use in this crazy landscape? What is the difference between all these tools?

Nick Humrich will attempt to walk you through this maze and help you understand what all these things do and why they exist. Nick did this same talk 1 year ago. If you attended that one, come see how things have changed in just 1 year.