Can we Biohack and Mindhack to have a Long Life Full of Mission and Purpose?

A documentary on biohacker Bryan Johnson has just been released on Netflix. He can teach us many lessons about longevity.

However, as Dr Peter Attia says, "If our life sucks, living longer is actually a curse, not a blessing", and he notes that the medical profession does not focus enough on developing individuals' mission and purpose. See: https://www.youtube.com/watch?v=b_d-drdcfJo from 16:30.

How do we live longer lives?

How do we lead long fulfilling lives full of mission and purpose?

Note: Each individual needs to receive medical and dietary advice specific to themselves. Each individual also needs to decide on their own mission and purpose!