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Title: What Is Progress? Knowledge Aggregation, Living Textbooks, and the Automation of Scientific Discovery Date: June 20 2026 Noon - 14:00 EDT Summary: Our collective knowledge infrastructure — the textbooks, professional training resources, and literature syntheses that define what professionals across disciplines believe to be true — is quietly accruing a structural liability. Compounded confirmation bias, stacked citation-by-citation into the foundations of formal knowledge, means that breakthroughs can take decades to reach the classrooms, clinical workflows, and decision-making frameworks where they matter most. Meanwhile, the deepest friction is rarely acknowledged: before any field can build meaningful consensus on "why" or "how" a phenomenon occurs, it must first establish honest, consolidated agreement on "what" has actually been observed. That prior step is routinely skipped, assumed, or fragmented across siloed literatures that never cross-pollinate. This talk introduces a framework called "Knowledge Aggregation" — with two distinct but complementary ambitions. The first is descriptive transparency: algorithmically mapping what has been said, measured, and documented across a problem space, without imposing causal interpretation or narrative. The second traces the boundary between empirical observation and explanatory claim, building systems that can separate the "what" from the "why/how" — because consensus on mechanism cannot be meaningfully constructed until consensus on phenomenon is first established. Both ambitions are now within reach. By composing tools already at our disposal — large language models, classical NLP pipelines, public data repositories, and engineering-grade automation frameworks — it becomes possible to model knowledge itself, rather than merely imitate individual experts. One concrete expression of this is automating the writing of living textbooks: compressing the lag from bleeding-edge discovery, through replicated evidence, all the way to professional training resources. But the deeper aspiration reaches further — toward automating the discovery of scientific insights that have never previously been conceived, by systematically surfacing hypothesis combinations that no single siloed researcher would have had the cross-disciplinary vantage point to even ask. Drawing on ongoing systems biology and computational research — with ME/CFS research demoed as a use case for what siloed, fragmented knowledge infrastructure costs in practice — this talk maps the conceptual architecture, the real-world friction, and the data science toolkit for building it. Speaker: As a systems biologist at heart, Sam specializes his biomedical research on interactions and connections in biology - rather than just one domain of expertise. He wears many hats and collects skill sets across disciplines, with degree studies and industry experience acquired across Chemical Engineering (BSc), Bioinformatics (MSc), Systems and Synthetic Biology (M2), Biomedical Sciences (MSc), and beyond. Even more important to him than niches or fields of work, comes down to the synergistic approaches that allow us to move beyond reductionism. The notion that a question can only allow for one answer, is inherently reductionist. By resisting many norms in science and engineering which can get overly reductive, his current role as Principal Investigator of Research for DMV Petri Dish (501(c)(3) non-profit local to the DMV region) embraces computational frameworks that aide scale-up and automation - not only around the processes which already exist with established workflows, but also taking a keen interest in attempting and accomplishing ambitions which have never been perceived to be possible previously. Sam carries a passion for the synergy of computational biology - fused with wet lab validation. This way, one can build a beautiful knowledge base in the theoretical sense, and then test to see if said computational prediction might actually be able to stand in the real world with wet lab validation. Translational modeling starts to become possible once biological experiment design can be iteratively looped alongside computational model design, optimization, and analysis - empowering the design of a better wet lab experiment, followed by a better computational model, back and forth until science is done!

**When**: Every Third Saturday of the Month, 2:00-5:00 pm **Where**: Pyramid Atlantic's Helen Frederick Gallery (2nd Floor) Pyramid Atlantic Art Center\* 4318 Gallatin Street, Hyattsville, MD 20781 Convenient cheap parking in several very close municipal parking lots including parking in lot next to Franklin's. 0.50 cents/hour until 8pm **What**: Join us for an uninstructed life drawing session with a themed costume model. Bring your own art materials. Chairs, portable easels and drawing boards provided on a first-come-first-serve basis. **Cost**: $20/session or $75/5-session punch card Walk-ins and late arrivals welcome, no experience necessary! **Etc**.: To protect the privacy of our modes, no photography please. **Contact**: Milena- hyattsvillefiguredrawing@gmail.com \*Membership to Pyramid Atlantic, though not required, is very enthusiastically encouraged! [Pyramid Atlantic Membership](https://pyramidatlanticartcenter.org/support/membership/) *We are not looking for new figure models at this time, no inquiries please. Thank you.*

Hello everyone! Please join Japanese conversation group at Arlington Central Library group room. Where: Arlington Central Library, Wilson Room max 12 people Who: People who want to speak in Japanese or listen to Japanese conversation \-\- Both native speakers and language learners are welcome\! \-\- Feel free to chat about Japanese culture\, food\, anime\, etc\. Access by DC Metro：Metrostation is nearby, **Ballston-MU** and **Virginia Square-GMU** Access by car: Library has parking space. Parkmobile spaces available around the library \*We can go to Japanese restaurant or something after library room is closed. PARTICIPATION GUIDELINES: \-\- If you are new\, feel free to introduce yourself to Jun\. \-\- Please speak in Japanese as much as possible\. That being said\, people seeking listening practice are also welcome\! \-\- Try not to dominate conversations when someone else is trying to contribute\. If it helps\, strike up or join a conversation with different people\. \-\- If you feel uncomfortable for any reason \(conversation topic\, attendee\, etc\.\)\, please speak up\. If you would prefer to let us know in private\, contact \(240\) 544\-7230 or [nagahana@gmail.com.](http://nagahana@gmail.com./) We look forward to seeing you there!

Step into style with this unique and creative workshop led by Susanne! In this class, you'll learn how to turn a simple quilted sandwich made from fat quarters (completed prior to class) into a fabulous, one-of-a-kind pair of quilted sneakers. From the sole up, you’ll stitch, shape, and strut your way through the process — walking away with handmade kicks that are as bold and original as you are! Your registration fee includes the $60 cost of the sneaker soles and a supply kit from Susanne. Note: **students MUST** **register and email your sole size & color choice** **to Susanne by Wednesday, May 27 so she can order the sneaker soles from Europe** in time for class. For more information and to sign up, **[visit our website »](https://artisticartifacts.com/products/june-20-snazzy-sneakers-with-susanne-miller-jones)** *** Due to the size or other requirements of the class or concurrent scheduling, some classes are in our second-floor space: access is via stairs only. Registrations for all Artistic Artifacts classes MUST be paid for through our website at [https://artisticartifacts.com/collections/wk](https://artisticartifacts.com/collections/wk), or via a visit to our shop at 4750 Eisenhower Avenue. We encourage you to RSVP here, but to ensure your seat you MUST follow through via our website. View our complete class policies » [https://artisticartifacts.com/pages/class-policies](https://artisticartifacts.com/pages/class-policies)

NOTE: This working session is at West End Neighbourhood Library not MLK. It is near the Foggy Bottom Metro Station. A game development **Working Session** involves 3 key parts: 1. Tell people what you're going to do 2. Actually do stuff 3. Show people what you did **What to bring**: Laptop, Charger, maybe a power strip if you have one handy, any other game development tools you need. Try to download any software you need before the working session. There is Wifi at this location, but it may be slow if you have to download any large files.

This event is for volleyball beginners who want an opportunity to practice, play, and gain experience in a relaxed, low pressure environment. Whether you're trying volleyball for the first time or still developing confidence in the basics, you'll find this event welcoming, supportive, and beginner-friendly. Level: Beginners Cost: Free Field Type: Outdoor grass Format: 6x6 The focus will be on getting 3 touches on the ball, learning through play, and having fun with others who are also new to the game. Come enjoy some casual volleyball, meet new people, and have fun! **Where to find us:** Follow the trail and you will see an open grass field. Location pin- ground https://maps.app.goo.gl/apGAyMb7Urxxrdus9?g_st=ac **Smiley Social documents:** 1. [Group Rules](https://docs.google.com/document/d/1HrG35p_0M08leRvCp8XWG3CMkr_GL928XFabl5T6Dvg) 2. [Liability Waiver](https://docs.google.com/document/d/1W2mq-7m99lmvd7gdWYaSUFtvVg4UGnzV6koafAbHmco) 3. [Volleyball Levels](https://docs.google.com/document/d/1PojSi4qdlRsv1msCHhvpQ43iDc4FfzQwpWCc3kafVMY/)

Join us for **[Judy’s Altered Minds](https://artisticartifacts.com/pages/judy-s-altered-minds)**! Bring your fiber & mixed media show & tell; many members also enjoy making ATCs (**[artist trading cards](https://artisticartifacts.com/pages/judy-s-altered-minds)**) for exchange each month. **Come early to shop** (JAMs attendees receive a 10% discount on their purchases) — Artistic Artifacts is open Sundays 11:00 am - 4:00 pm. The JAMs meeting starts at 1:30 pm. New members are always welcome! A $3.00 contribution is requested at each meeting. JAMs members are art quilters, collage artists, art journal keepers, surface design enthusiasts, paper crafters, art doll/assemblage artists and more! All levels of expertise are represented, and all are welcome. During JAMs meetings, attendees gather support and encouragement for their art through show & tell and enjoy the camaraderie of like-minded friends.

**THE POWER OF THE SUBCONSCIOUS OVER YOU** You are welcome to arrive 15 minutes early for refreshments! At the lecture "The Power of the Subconscious", the speaker will clearly and understandably explain topics such as: * What is the exact definition of the Subconscious Mind? * How does it inflict unwanted feelings and anxiety in you? * What determines how much pressure it exerts on a person? * What exactly is the goal of the subconscious? This is not just a lecture where you sit quietly and listen. It's interactive and LIVE, so you can ask questions at any time. And the most important topic: **HOW DO YOU TAKE CONTROL OF YOUR SUBCOUNSCIOUS!** This group is sponsored by the Dianetics Life Improvement Center.

Playtesting Agent and Battle-scale of the Zone-17 role-playing and miniatures game.

[Book Your Classes by Clicking This Link! ](https://crowndancestudio.com/group-classes/) Take a deep dive into the world of Latin rhythm with our **Level 2 Bachata workshop from 1:30 PM to 3:00 PM**. This 90-minute intensive is crafted for dancers who have moved past the basics and are ready to refine their body mechanics, intricate footwork, and partner connection. **For $25,** you’ll receive focused, high-value instruction that bridges the gap between foundational steps and social dance mastery, ensuring you leave the studio feeling confident and inspired

Do you want more Self Confidence, less Self Doubt, more Happiness, less Anxiety, and more Love? This event is an introduction to how to handle irrational emotion. How often are yours or another's emotions out of control? What is that about??? I have asked these questions and after much search have found answers and am sharing. Maybe you have suffered a traumatic experience, a deep loss or been through a painful breakup? After that, you try to move on- you just can't. Possibly you have a thought or emotion that hangs around for days and you just can't shake it. What is all this stress, anxiety, depression, and self doubt? It's just crazy! It's not the real you. You can find out what is at the root of all this. This is an in-person class that can start you on the way to a better life, more confidence and less negativity. All the happiness you have lies within you. Let's find it! We only use natural proven techniques, This group is sponsored by the Dianetics and Scientology Life Improvement Center.

Columbus Code & Coffee is an inclusive, informal co-working session. People of all skill levels attend, and we love it that way. Many people (optionally) bring projects to work on, and many other people (optionally) socialize the entire time. It's entirely up to you! **What to Expect at the Intro Circle** \~\~\~\~\~\~\~\~\~\~\~\~\~ Near the beginning of the event (1:30 pm), we do a standup: * Organizer announcements, updates, and logistics Round 1 - (7 secs max): * Your name * What you're working on * What you can help others with Round 2: * Community events you wanna plug. If none, that's cool too. Round 3: * Job opportunities you're hiring for OR announce that you are looking for one. If none, that's cool. After the introduction circle, everything is self-organized! Feel free to work alone, pair up, attend one of our workshops/presentations, or mingle!

**Important time note:** Please plan on arriving between 5:30 and 6:00 as the elevators lock after 6 and you'll need to message us and we'll need to come get you. The building address is 4450 Bridge Park The entrance is 6620 Mooney St, Suite 400 You will need to scan your ID at the door to get a visitor badge. **Abstract** *Customize the IDE: Building Extensions for Visual Studio Code* Visual Studio Code is one of the most widely used development environments today, and much of its flexibility comes from its extension ecosystem. Extensions allow developers to customize the editor with new features, integrations, and workflow improvements tailored to their needs. In this session, we’ll cover what extensions are and the different types available, including full extensions written in TypeScript or JavaScript, along with lighter-weight extensions such as color themes, language packs, language support, code snippets, and keymaps. We’ll also look at practical reasons a developer might create an extension, from automating repetitive tasks to adding custom tooling. The session includes a hands-on walkthrough of creating a new extension, testing it locally, and understanding the basic project structure. We’ll close with a brief overview of how extensions are packaged and published to the Visual Studio Marketplace and other distribution options. **YouTube Link** TBD

We are bringing Microsoft Build sessions to Columbus Ohio! The Central Ohio Azure Meetup and Central Ohio .NET Developer's Group (CONDG) are coming together to bring some of the labs and breakouts from Microsoft Build to your backyard. In this free, 1 day event, you are going to Build stuff with us! And yes, there will be free food. Please RSVP via [Microsoft Build //localhost:columbus | Microsoft Reactor](https://developer.microsoft.com/en-us/reactor/events/27247/).

Columbus Code & Coffee is an inclusive, informal co-working session. People of all skill levels attend, and we love it that way. Many people (optionally) bring projects to work on, and many other people (optionally) socialize the entire time. It's entirely up to you! **What to Expect at the Intro Circle** \~\~\~\~\~\~\~\~\~\~\~\~\~ Near the beginning of the event (1:30 pm), we do a standup: * Organizer announcements, updates, and logistics Round 1 - (7 secs max): * Your name * What you're working on * What you can help others with Round 2: * Community events you wanna plug. If none, that's cool too. Round 3: * Job opportunities you're hiring for OR announce that you are looking for one. If none, that's cool. After the introduction circle, everything is self-organized! Feel free to work alone, pair up, attend one of our workshops/presentations, or mingle!

# 💞 Zoom Speed Dating: Detroit Singles, One Night _A handful of quick, real conversations with Detroit singles — paired to you by age and vibe, all from wherever you're comfiest._ **Four easy steps:** 1. Sign up and answer a few quick personality questions 2. Hop onto Zoom right as we kick off 3. Chat one-on-one through guided rounds 4. Wake up to your mutual matches in your inbox --- **Pick your group below and you're in:** 💘 **Ages 18-32** → [Grab your spot](https://theliveround.com/product?productId=574&productType=onlineSpeedDating&city=Detroit&groupurlname=cityscape-navigators-park-orienteering-team&ar=18-32&face_v=9.0) 💘 **Ages 30-46** → [Grab your spot](https://theliveround.com/product?productId=574&productType=onlineSpeedDating&city=Detroit&groupurlname=cityscape-navigators-park-orienteering-team&ar=30-46&face_v=9.0) 💘 **Ages 40-58** → [Grab your spot](https://theliveround.com/product?productId=574&productType=onlineSpeedDating&city=Detroit&groupurlname=cityscape-navigators-park-orienteering-team&ar=40-58&face_v=9.0) 💘 **Ages 55+** → [Grab your spot](https://theliveround.com/product?productId=574&productType=onlineSpeedDating&city=Detroit&groupurlname=cityscape-navigators-park-orienteering-team&ar=55+&face_v=9.0) > ⚠️ Don't get caught out: RSVP alone won't seat you. Register via your age group and take the quiz to hold your place. Spots go fast. **Someone good is one click from saying hi. 💞**

## Candle Making Night at The Arcane Foundry \| Design Your Own Custom Candle **SPECIAL PROMOTION**: Buy 3 and get 1 Free! Step into The Arcane Foundry and create your own custom candle from start to finish. This is a laid back, hands-on experience where **you’ll blend fragrances, choose your vessel, and pour your own candle using 100% soy wax**. Whether you’re coming solo or with friends, it’s designed to be simple, creative, and a good time. We’ll walk you through the entire process, from picking your scents to choosing between a traditional cotton wick or a crackling wood wick. You can go with one fragrance or mix your own blend to create something completely unique**. No experience needed**, just show up and we’ll handle the rest. While your candle sets, feel free to hang out, play a game, explore the shop, or just relax and talk. Drinks and snacks are available, and the atmosphere leans into the **fantasy**, **dark academia**, and **gothic horror** vibe The Arcane Foundry is known for. Learn More: [Candle Making in Columbus, Ohio at The Arcane Foundry](https://thearcanefoundry.com/candle-making/) *** ### What to Expect: * Guided candle making experience * Choose your own vessel, wax, wick, and fragrance * 100% soy wax candles * Optional drinks and snacks * Time to relax while your candle cools *** ### Important Notes: * Please arrive on time so we can start together * Candles will need time to set before taking home * This is a beginner-friendly event *** ### RSVP Required Reserve your spot on Meetup to lock in your seat. **Candle Making** (includes vessel, your choice of wick, wax, scented oil, labels and lids) 5oz Glass Jars $15 8oz Candle Tins $25 12oz Glass Candles $35 12oz Amber Jars $40 16 oz Skull or Jack o Lantern Candle Mugs $65 (Limited Edition!) **All materials included. You just bring yourself (and your drink of choice).** **Payments accepted:** * Credit Card * Venmo: @Daclaud-Lee * Cashapp: $DaclaudL

We are going to build together with all the CLIs! E will be doing it at Columbus Code and Coffee Agenda --- Hosted By James Power, Organizer Pete Gordon, Organizer Just a Software Guy in the age of the Internet. Complete your event RSVP here: https://gdg.community.dev/events/details/google-gdg-columbus-presents-ai-improv-lets-build-a-game-together-with-claude-code-codex-and-gemini-and-be-the-judge/.