Automated Machine Learning

Title: What Is Progress? Knowledge Aggregation, Living Textbooks, and the Automation of Scientific Discovery Date: June 20 2026 Noon - 14:00 EDT Summary: Our collective knowledge infrastructure — the textbooks, professional training resources, and literature syntheses that define what professionals across disciplines believe to be true — is quietly accruing a structural liability. Compounded confirmation bias, stacked citation-by-citation into the foundations of formal knowledge, means that breakthroughs can take decades to reach the classrooms, clinical workflows, and decision-making frameworks where they matter most. Meanwhile, the deepest friction is rarely acknowledged: before any field can build meaningful consensus on "why" or "how" a phenomenon occurs, it must first establish honest, consolidated agreement on "what" has actually been observed. That prior step is routinely skipped, assumed, or fragmented across siloed literatures that never cross-pollinate. This talk introduces a framework called "Knowledge Aggregation" — with two distinct but complementary ambitions. The first is descriptive transparency: algorithmically mapping what has been said, measured, and documented across a problem space, without imposing causal interpretation or narrative. The second traces the boundary between empirical observation and explanatory claim, building systems that can separate the "what" from the "why/how" — because consensus on mechanism cannot be meaningfully constructed until consensus on phenomenon is first established. Both ambitions are now within reach. By composing tools already at our disposal — large language models, classical NLP pipelines, public data repositories, and engineering-grade automation frameworks — it becomes possible to model knowledge itself, rather than merely imitate individual experts. One concrete expression of this is automating the writing of living textbooks: compressing the lag from bleeding-edge discovery, through replicated evidence, all the way to professional training resources. But the deeper aspiration reaches further — toward automating the discovery of scientific insights that have never previously been conceived, by systematically surfacing hypothesis combinations that no single siloed researcher would have had the cross-disciplinary vantage point to even ask. Drawing on ongoing systems biology and computational research — with ME/CFS research demoed as a use case for what siloed, fragmented knowledge infrastructure costs in practice — this talk maps the conceptual architecture, the real-world friction, and the data science toolkit for building it. Speaker: As a systems biologist at heart, Sam specializes his biomedical research on interactions and connections in biology - rather than just one domain of expertise. He wears many hats and collects skill sets across disciplines, with degree studies and industry experience acquired across Chemical Engineering (BSc), Bioinformatics (MSc), Systems and Synthetic Biology (M2), Biomedical Sciences (MSc), and beyond. Even more important to him than niches or fields of work, comes down to the synergistic approaches that allow us to move beyond reductionism. The notion that a question can only allow for one answer, is inherently reductionist. By resisting many norms in science and engineering which can get overly reductive, his current role as Principal Investigator of Research for DMV Petri Dish (501(c)(3) non-profit local to the DMV region) embraces computational frameworks that aide scale-up and automation - not only around the processes which already exist with established workflows, but also taking a keen interest in attempting and accomplishing ambitions which have never been perceived to be possible previously. Sam carries a passion for the synergy of computational biology - fused with wet lab validation. This way, one can build a beautiful knowledge base in the theoretical sense, and then test to see if said computational prediction might actually be able to stand in the real world with wet lab validation. Translational modeling starts to become possible once biological experiment design can be iteratively looped alongside computational model design, optimization, and analysis - empowering the design of a better wet lab experiment, followed by a better computational model, back and forth until science is done!

Hey Poetry Lovers! This group is on a roll. Here’s the gist: We meet at the **Capital One Café in Chinatown** from **12pm - 2pm** every other week. For enrichment, we start by reading and reflecting on a **“published poem”**, suggested by someone in the group. No advance preparation is necessary. But feel free to check out some of the poems we’ve read [here](https://docs.google.com/spreadsheets/d/e/2PACX-1vSyE_wCLQCPHRrKmN5F9tOIeeRQUZESxjRXGVBoCF2uU8Gm0_d0uECiCBCQXEy6ksxfsBOhtRIOpW3T/pubhtml?gid=0&single=true&widget=true&headers=false%22%3E%3C/iframe%3E). Or submit suggestions for future meetings [here](https://docs.google.com/forms/d/e/1FAIpQLSexGc2Z2Kp6bZW0D3_hfJ7NUUkfNHf7TXX-43FglCeBd9EF2Q/viewform?usp=send_form). Next, we **share our work and offer feedback**. Depending on attendance, everyone gets \~10 minutes to use as they like. (No need to share, though; you’re welcome to come even if you prefer just to listen.) We maintain a **Discord server** to help share our work and communicate outside our bi-weekly meet-ups. If you haven’t used Discord before, take a moment to download it and create an account before arriving. When we meet you on Saturday, we will add you to our server, the “DC Poetry Workshop”, and can help you navigate the app if you have questions. Finally, if you plan on sharing a poem, consider how you will do so. Some options include: * Print 5-10 copies to distribute in person * Take and share screenshots in the Discord chat. * Copy the poem into a google doc, change sharing settings to “anyone with link”, and copy the google doc link into the Discord chat. Most importantly, we’re excited to meet you! Catch you on Saturday, Diego / Ian / Cayden / Nate / Otasha / Lia / An

Venez apprécier l'ambiance chaleureuse d'une conversation en français autour d'un verre de vin et d'apéritifs. C'est ouvert à tous quelque soit votre niveau, que vous soyez intermédiaire/avancé ou bien que le Français soit votre langue maternelle. ***GRAB A DRINK AND YOU WILL BE ALL SET TO FLEX YOUR LANGUAGE CAPACITY. YOU NEED TO GET AT LEAST A DRINK OR FOOD :) To get the event going and show support. We know that you like our events. P.S. : We have non-alcoholic drinks as well.*** We have a tiny venue and we hit capacity often and early arrival is suggested. We have the discretion to decide entry. It is irresistible, to enjoy French convo with a glass of wine, appetizers and drinks. The Event is open to all levels of French language, from intermediate to native fluency. This is mainly a social for Intermediate/Advanced/Native Speakers. It is not as such to learn a language. Beginners, if you want to learn a language, reach out to us ([info@merevents.com](http://info@merevents.com/)). We have a school and will arrange you a class. ***AFTER THE HAPPY HOUR, WE HIT THE DANCE FLOOR! BRING YOUR DANCING*** [http://www.youtube.com/watch?v=6Vv1wxZAR1k](http://www.youtube.com/watch?v=6Vv1wxZAR1k)

[Book Your Classes by Clicking This Link! ](https://crowndancestudio.com/group-classes/) Take a deep dive into the world of Latin rhythm with our **Level 2 Bachata workshop from 1:30 PM to 3:00 PM**. This 90-minute intensive is crafted for dancers who have moved past the basics and are ready to refine their body mechanics, intricate footwork, and partner connection. **For $25,** you’ll receive focused, high-value instruction that bridges the gap between foundational steps and social dance mastery, ensuring you leave the studio feeling confident and inspired

We'll be offering a Free Learn to Skate Clinic 10am Saturday next to the Carter Barron Amphitheatre parking lot in Rock Creek Park. We'll cover everything you need to start skating outdoors. Inline and roller skaters welcome; protective gear required (check our meetup group description for details). We have loaner skates and protective gear available. If you need to borrow gear, please contact us at least a couple of days in advance of this session so we'll know to bring it for you. If you need skates, please specify roller skates or inlines and also men's or women's sizes. A note on our start time: * Please be there by 930am if you plan to borrow gear so you have enough time to try things on and make sure everything fits. * Please be there by 945am if you have your own gear so you have enough time to put it on. * The clinic starts promptly at 10am; if you're not geared up and ready when we start, it'll be hard to include you in the session.

[Book Your Classes by Clicking This Link! ](https://crowndancestudio.com/group-classes/) Start your weekend with elegance and poise during our **Beginner’s Ballroom sessions at 10:30 AM and 11:15 AM**. These classes provide a welcoming, family-friendly environment where students of all ages can learn the fundamental steps of classic dances like the Tango and Rumba. Focusing on grace, posture, and the joy of movement, these sessions are **priced at $18 per class,** offering an accessible way to master the "American Smooth" styles in a relaxed morning setting. 10:30 1 American Smooth Dance. 11:15 I American Rhythm Dance. Cost: $18 for 1 Class. $25 for 2 Classes.

We'll check out 29th Parallel Coffee in Fairfax Station. We plan to grab a coffee and head to Burke Lake Park and walk around the lake (weather permitting). There are a couple of parking areas at the park. I marked the parking we're planning to meet at the park. We hope to start the walk around 11:30AM. If you're a Fairfax County resident (with an ID), parking is free, otherwise they charge for parking. Please have a picture profile so we can recognize you in the meetup.

PLEASE CHECK THE ONLINE MEDITATION CALENDAR FOR DETAILS OF THESE MORE THAN 50 SERVICES A WEEK- https://onlinemeditation.yogananda.org/calendar/

Do you want more Self Confidence, less Self Doubt, more Happiness, less Anxiety, and more Love? This event is an introduction to how to handle irrational emotion. How often are yours or another's emotions out of control? What is that about??? I have asked these questions and after much search have found answers and am sharing. Maybe you have suffered a traumatic experience, a deep loss or been through a painful breakup? After that, you try to move on- you just can't. Possibly you have a thought or emotion that hangs around for days and you just can't shake it. What is all this stress, anxiety, depression, and self doubt? It's just crazy! It's not the real you. You can find out what is at the root of all this. This is an in-person class that can start you on the way to a better life, more confidence and less negativity. All the happiness you have lies within you. Let's find it! We only use natural proven techniques, This group is sponsored by the Dianetics and Scientology Life Improvement Center.

**GO TO EVENTBRITE FOR LINK TO MEETING:** https://www.eventbrite.com/e/recovering-from-religion-virtual-support-group-meeting-registration-159506756001?aff=oddtdtcreator This is an RfR-wide event, not tied to any particular local chapter. The Virtual Chapter Recovering From Religion support group will meet the the 1st Sunday of each month at 6 PM Central Time AS WELL AS at the 3rd Saturday of each month at 9 AM. This meeting will be held virtually via Zoom. Attendees are welcome to share, but may also decide to remain anonymous if they so choose. The primary focus of a Recovering From Religion support group is to provide ongoing and personal support to individuals as they let go of their religious beliefs. This transitional period is an ongoing process that can result in a range of emotions, as well as a ripple effect of consequences throughout an individual’s life. As such, the support meetings are safe and anonymous places to express these doubts, fears, and experiences without biased feedback or proselytizing. We are here to help each other through this journey. There is no cost to attend this support group but, if you feel so inclined, donations can be made at www.recoveringfromreligion.org/donate If you find you need to talk with someone before the meeting date, RfR has a hotline and online chat for that express purpose. Call (844) 368-2848 to speak with someone. Go to www.recoveringfromreligion.org and click on the green chat bubble in the lower left corner of the site to chat online. If you are in need of professional help, we can offer the Secular Therapy Project to provide options to connect with a professional therapist. All therapists have been thoroughly vetted by our organization and offer only evidence-based and non-religious treatment. Connect with them at www.seculartherapy.org. Like what RfR does? Why not volunteer! There are quite a few options. Head over to www.recoveringfromreligion.org/volunteer for more info.

The Group gathers in the parking lot between 6:00 AM and 6:30 AM to catch the sunrise over the Potomac River. Google Maps: [https://maps.app.goo.gl/hCUuoxUPKhRbLLZn9](https://maps.app.goo.gl/hCUuoxUPKhRbLLZn9) Dyke Marsh Wildlife Preserve is known as a top regional birding spot; over **300 species** have been recorded here, including nesting bald eagles and ospreys. Bring your longest telephoto lens and binoculars. I can help you with camera settings so you can capture sharper images of both perched birds and birds in flight. It is thrilling to capture the amazing orange and red colors that are only available at that time in the morning. Share only your very best, most interesting shots after the field trip, and keep it down to between 5 and 10 photos. Bring water, comfortable shoes, a tripod, fully charged batteries, and empty memory cards... Park Facts: Entrance Fee: Free Allow Dogs on a leash: Yes Bathroom: On the north side of the Marina is a building for restrooms National Park Service Dyke Marsh Wildlife Preserve: www.nps.gov/gwmp Friends of Dyke Marsh (www.fodm.org) By sending in an RSVP and joining this meetup event hosted by the Virginia Beltway Photography Meetup, I agree to abide by the rules and regulations (where applicable) of the event location, and I am also agreeing to the terms of the following release and waiver of liability, which shall be binding on my heirs, executors, administrators, successors, and assigns. In consideration of my (and my child’s) participation in the Virginia Beltway Photography Meetup, I do hereby release, discharge, and hold harmless the Organizer, its members, officers, directors, employees, and the leader(s) of this event from any and all liability by reason of any damage, loss, expenses, or injury arising from my (and my child’s) participation in this event, including that caused solely or in part by the fault of any and all of the above-named parties.

Come join us for the weekly open mic night and enjoy a mix of comedy, poetry, and music!

We’re still working to get more people into these Meetups, but our goal is to give PlayYourCourt members a few social tennis outings each week in addition to your practice sessions and Challenge League matches. These Meetups are co-ed, super laid back, and all skill levels are welcome. Post your skill level and a suggested court in the comments section so we can round up as many players as we can for some tennis fun! Also, if you’re looking to meet new practice partners or play some matches and you aren’t already in the PlayYourCourt Community, you can go here to see what we’re all about and sign up: https://www.playyourcourt.com/tennis-community/washington-dc/meetup/ If you love tennis, we’d love to have you! Be sure and watch the quick video that explains how everything works. Happy hitting! - Scott

Come support Velocity's Monthly Warehouse Sale! We'll need help moving bicycles outside the warehouse before 9 a.m. and back inside at 1 p.m. In between, we'll greet customers, help them find bicycles and parts, and ring up their purchases on Square. Feel free to sign up even if you can't volunteer for the whole time. And remember to wear clothes you don't mind getting dirty with bicycle grease! Please note that volunteers under 18 are required to have a parent or guardian attend the beginning of their first volunteering session in order to sign a waiver for them, and volunteers under 16 are required to have a parent or guardian present with them during all the time they spend volunteering at Velocity.

**Important time note:** Please plan on arriving between 5:30 and 6:00 as the elevators lock after 6 and you'll need to message us and we'll need to come get you. The building address is 4450 Bridge Park The entrance is 6620 Mooney St, Suite 400 You will need to scan your ID at the door to get a visitor badge. **Abstract** *Customize the IDE: Building Extensions for Visual Studio Code* Visual Studio Code is one of the most widely used development environments today, and much of its flexibility comes from its extension ecosystem. Extensions allow developers to customize the editor with new features, integrations, and workflow improvements tailored to their needs. In this session, we’ll cover what extensions are and the different types available, including full extensions written in TypeScript or JavaScript, along with lighter-weight extensions such as color themes, language packs, language support, code snippets, and keymaps. We’ll also look at practical reasons a developer might create an extension, from automating repetitive tasks to adding custom tooling. The session includes a hands-on walkthrough of creating a new extension, testing it locally, and understanding the basic project structure. We’ll close with a brief overview of how extensions are packaged and published to the Visual Studio Marketplace and other distribution options. **YouTube Link** TBD

Most people still use AI like a search box: type one question, get one answer, repeat. But the next step is AI agents: systems that can take a goal, break it into steps, use tools, remember context, and produce useful work for a human to review. In this beginner-friendly session, we’ll demystify what AI agents actually are — without hype or jargon. We’ll walk through practical examples of how agents can help with research, planning, writing, coding, operations, and personal productivity. We’ll cover: * What makes an AI “agent” instead of just a chatbot * How agents break tasks into steps * Where agents are genuinely useful today * Where they fail, hallucinate, or need human review * How to design simple AI workflows for your own work * A live demo of an AI agent-style workflow from start to finish No coding experience required. This is for anyone who wants to understand where AI tools are going and how to use them more effectively right now. LOGISTICS AND PARKING: The talk starts at 7:00 PM. The first half hour is reserved for everyone to get set up and mingle. Free pizza and drinks! The cheapest parking option is to find street parking, which will only cost you a few bucks. Otherwise, park in the nearby veteran's museum lot for $8. It's highly recommended you avoid the nearby $15 garage parking.

## Candle Making Night at The Arcane Foundry \| Design Your Own Custom Candle **SPECIAL PROMOTION**: Buy 3 and get 1 Free! Step into The Arcane Foundry and create your own custom candle from start to finish. This is a laid back, hands-on experience where **you’ll blend fragrances, choose your vessel, and pour your own candle using 100% soy wax**. Whether you’re coming solo or with friends, it’s designed to be simple, creative, and a good time. We’ll walk you through the entire process, from picking your scents to choosing between a traditional cotton wick or a crackling wood wick. You can go with one fragrance or mix your own blend to create something completely unique**. No experience needed**, just show up and we’ll handle the rest. While your candle sets, feel free to hang out, play a game, explore the shop, or just relax and talk. Drinks and snacks are available, and the atmosphere leans into the **fantasy**, **dark academia**, and **gothic horror** vibe The Arcane Foundry is known for. Learn More: [Candle Making in Columbus, Ohio at The Arcane Foundry](https://thearcanefoundry.com/candle-making/) *** ### What to Expect: * Guided candle making experience * Choose your own vessel, wax, wick, and fragrance * 100% soy wax candles * Optional drinks and snacks * Time to relax while your candle cools *** ### Important Notes: * Please arrive on time so we can start together * Candles will need time to set before taking home * This is a beginner-friendly event *** ### RSVP Required Reserve your spot on Meetup to lock in your seat. **Candle Making** (includes vessel, your choice of wick, wax, scented oil, labels and lids) 5oz Glass Jars $15 8oz Candle Tins $25 12oz Glass Candles $35 12oz Amber Jars $40 16 oz Skull or Jack o Lantern Candle Mugs $65 (Limited Edition!) **All materials included. You just bring yourself (and your drink of choice).** **Payments accepted:** * Credit Card * Venmo: @Daclaud-Lee * Cashapp: $DaclaudL

**Improving Office in Franklinton** Physical location: Improving Office 330 Rush Alley Suite #150 Columbus, OH 43215 Schedule: 6:00 p.m.: Socialize, eat, and drink. Improving will be providing pizza and beverages. 6:30 to 8:00 pm. Main meeting and presentation(s). Topic: This month Chris Pazsint will be talking about Agentic Coding. How does one use CLI Based Agents, and Agentic IDEs such as Cursor, Kiro, Antigravity? How to include agentic coding plugins for IDEs you already love such as Visual Studio Code. We meet on the last Monday of each Month. Presentations are given by members and friends of this group. If you would like to do a presentation (small or large) on a python topic, please contact Central OH Python at centralohpython@gmail.com

We are bringing Microsoft Build sessions to Columbus Ohio! The Central Ohio Azure Meetup and Central Ohio .NET Developer's Group (CONDG) are coming together to bring some of the labs and breakouts from Microsoft Build to your backyard. In this free, 1 day event, you are going to Build stuff with us! And yes, there will be free food. Please RSVP via [Microsoft Build //localhost:columbus | Microsoft Reactor](https://developer.microsoft.com/en-us/reactor/events/27247/).

Welcome to Drunken Philosophy, a casual, curious, social discussion club. Come grab a drink and a seat at The Oracle. **Optional topic for this meetup: Where is everybody?** In 1950 the physicist Enrico Fermi was talking about aliens over lunch and asked a question that still has not gone away: if the universe is so vast and so old, and even a fraction of those billions of stars have planets, where is everyone? By the numbers the galaxy should be crowded with civilizations. Instead we look up and hear silence. That gap between "they should be everywhere" and "we see no one" is the Fermi Paradox. One of the most unsettling answers is the idea of a **Great Filter**: somewhere on the road from dead chemistry to a galaxy-spanning civilization, there is at least one step that is almost impossible to get past. Maybe the filter is behind us. Maybe life starting at all, or simple cells becoming complex, or intelligence ever evolving, is the freak accident, and we already cleared the hard part. Or maybe the filter is ahead of us, and advanced civilizations reliably wipe themselves out before they spread. Here is the part that messes with people. If we ever found life somewhere else, even pond scum on Mars, most people would call it the greatest discovery in history. But it might be the worst possible news. It would mean life is common, the early steps are easy, and the hard step is still in front of us. So the eerie silence overhead might actually be the best sign we could ask for. **Questions to wrestle with:** * Is it better to be alone? Would you rather we find alien life and learn we are not special, or find nothing and quietly improve our odds of surviving? * Where do you bet the filter sits, behind us or ahead of us, and why? * If it is ahead of us, what is it? Nuclear war, climate collapse, AI, something we cannot even picture yet? And can we do anything about a filter we cannot see coming? * Two principles pull opposite ways here. The principle of mediocrity (the Copernican principle, Sagan's "no privileged place in the universe") says we are ordinary, so what happened on Earth probably happened everywhere, which makes the silence scream louder. The anthropic principle says of course we find ourselves somewhere life was possible, since we could not observe anything else, so our being here may say almost nothing about how common life is. Which lens do you trust, and does the silence still demand an answer once you account for observer selection? * And if we did confirm life out there and had to accept we are not special, what would that do to belief in a higher power, and would shedding (or keeping) that belief help or hurt our odds of pulling together as one species? * Does any of this change how you live, or how humanity should be spending its time and money right now? As always the prompt is optional. Come for the conversation, stay for the drinks, and bring your own questions.