BioInformatics

**Hosted by Pure Storage** Please note at the Pure Storage office, all meetup attendees will be required to sign a generic NDA used for all office visitors to be able to attend the meetup. Doors are open from 17:30, talks will start 18:00, and we have 2 talks and panel discussion. **1\. Daniel Turecek \(Pure Storage\) \- What is new in Go 1\.26** In this lightning talk, we’ll tour what’s coming in **Go 1.26** (based on the current draft release notes) and why it matters for real-world services. We’ll cover runtime and performance wins like the default **Green Tea GC**, faster **cgo** calls, improved stack allocation, and new profiling options aimed at spotting goroutine leaks. We’ll also look at security and crypto upgrades including 64-bit heap address randomization, the new **`crypto/hpke`** package, and **post-quantum hybrid key exchange on by default in TLS**. Finally, we’ll touch on pragmatic developer-experience changes—from `new(expr)` and richer generics constraints to tooling updates like `go fix`, `pprof` flame graphs by default, and compatibility-oriented module defaults. **2\. Vilibald Wanca \- Nail the Basics \- S01E02** Good Go code starts with a simple, predictable layout. In this talk, we’ll cover the standard approach to structuring Go projects: keep things flat early on, map one package to one directory, and keep tests right next to the code they validate (like `user.go` and `user_test.go`). We’ll also look at common structural mistakes—such as over-engineering too soon or importing Java/Python-style layering that fights Go’s package model—and how to avoid them. Finally, you’ll leave with a handful of quick wins you can apply immediately: formatting and import automation with `gofmt`/`goimports`, stronger feedback loops with `golangci-lint`, and editor setups (VSCode Go extension or GoLand) that make the “Go way” feel effortless. **3\. Panel discussion with our speakers on AI tools and Go development** Join us for a panel discussion with our speakers on how AI tools are changing Go development in practice. We’ll compare real workflows for using assistants to design, code, test, refactor, and review Go services—what actually saves time, what introduces risk, and where humans still need to stay firmly in the loop. Expect practical tips on prompt patterns, maintaining code quality, avoiding “AI-shaped” over-engineering, and integrating AI into existing tooling like linters, editors, and CI. Bring your questions—we’ll keep it candid, concrete, and Go-focused.

We’ve got another portion of AI talks for you, so come to our second Prague Gen AI Meetup of the year. ## NEW VENUE (very important) **Pracovna & Laskafe** Vlkova 628/36, 130 00 Praha 3-Žižkov ## Venue Schedule * **18:30** Doors open * **18:45** Talks start * **20:45** Talks end * **21:00** Snacks and beer ## What’s On The Agenda * **Talks:** Again, no hype, just the stuff you want to know. * **Snacks and Beer:** Grab a bite and a brew while talking shop. * **Networking:** Meet other people in the field. No fluff, just good tech talk. ## Talks ### Šimon Podhajský (Head of AI @ Waypoint) **The Eval Flywheel: From "Works on My Laptop" to Systematic Quality** Most teams shipping GenAI products have no evaluation system. They have vibes, a few saved prompts, and hope. This talk doesn’t start with “build an eval suite”, it starts with **observability**: if you can’t see what’s happening in production, nothing else matters. From there, we build the **eval flywheel**, a practical pattern where production observability feeds error analysis, error analysis generates eval cases, and eval cases prevent recurrence. Your evaluation suite isn’t something you design upfront, it’s something that grows out of understanding your production failures. ### Ondřej Romancov (Engineering Lead @ Duvo.ai) **Building agents with agents** Duvo is building a platform for AI agents, and we’re running our engineering on agents too. Sharing practical tips and workflows we’ve found useful along the way. Let’s get down to the real talk.

In a world full of opinions, noise, and quick reactions, we often miss spaces for real dialogue — for slowing down, listening, and connecting with one another. This evening is an invitation to do exactly that. Join us for an open and friendly evening (in English & free of charge) dedicated to Automated Commonwealth (UBI - Universal Basic Income), can we use AI for people's welfare? Is it a basic income what we really need? We will brainstorm together in an Open Space–style format, where participants choose topics themselves, and what we want to discuss from this broad topic - questions to help you get inspired: Is it possible to achieve automated UBI? Is UBI what we need, or is it better social infrastructure? How do we start building such system? Afterwards, participants will form small groups to explore the questions and insights around the topics 18:00 – Doors open 18:15 – Introduction & topic selection 18:40 - We start discussions 19:40 - Closing session (sharing activities) 20:00 - Networking & Connect What to expect: A welcoming space for newcomers and regulars alike Be slightly pushed to socialise Open, participant-led small-group discussions on diverse perspectives No expertise required — everyone’s opinion matters! Safe, respectful, and judgment-free conversations More about sharing and reflecting than debating or convincing No pressure to speak — listening is just as valuable Not a lecture, not a debate club, and definitely not intimidating! Feel free to bring some snacks to share! Friendly dogs are welcome! If you are a regular that appreciate us and can help, or a newcomer who enjoyed the evening, and wants to help, we have recently set a patreon page where you can support us! https://www.patreon.com/cw/EarthSocietyDialogues

Come and join us for a hike to a city untouched by time and see some of the most unique sights in Czech Republic and Europe. The town became famous for producing the Prague Groschen coins, which were also used elsewhere in Europe at the time, and became the second most important town in the Kingdom of Bohemia. Distance : 10 Km (about 6 hours) Difficulty Rating : Easy to Moderate Tour Highlights: • Professional and friendly guide • Hassle-free day trip to Kutna Hora from Prague • Admission to the "Bone Chapel," a chapel decorated with human bones at the Ossuary of the Cemetery Church of All Saints • Admission to the Gothic Cathedral of Saint Barbora • Admission to the Cathedral of the Assumption of Our Lady OPTIONAL • Hrádek - Czech Museum of Silver (Medieval Silver Mine) More information at https://www.facebook.com/events/1173596144588293/

Hello Beer Enthusiasts! 🍺 Indulge in a delightful beer tasting experience at the NuBeerBar, where they showcase the finest selection of Czech beers straight from their working pub with 11 Czech beers on tap. 📍 **Location:** NuBeerBar, Balbínova 1 📅 **Date:** Every Tuesday, from 27/02/2024 🕒 **Time:** 19:00-22:00 💸 **Event fee:** FREE 🍺 **Beers available**: https://www.nubeerbar.cz/en/#Ontap 💰 **Price**: 174 CZK (Set of 6 beers \* 0.12l at your choice from menu) **Event Details:** We have a table reserved at NuBeerBar, to explore the rich and diverse world of Czech beers through their tasting flights, the perfect way to sample a variety of Czech beers and discover your favorites. **What They Offer:** * **Tasting Flights**: Enjoy a flight of six different kinds of Czech beers carefully curated to highlight the unique flavors and characteristics of each brew. 🍻 * **Working Pub Atmosphere**: Immerse yourself in the lively ambiance of their working pub, where you can mingle with fellow beer lovers and enjoy the vibrant atmosphere. 🎶 * **Knowledgeable Staff**: Their friendly staff are always on hand to answer any questions you may have about the beers they offer and provide recommendations based on your preferences. 💬 *Whether you're a seasoned beer connoisseur or just starting to explore the world of Czech beers, the beer tasting event at the* NuBeerBar *promises to be a memorable experience for all.* We look forward to raising a glass with you and sharing our passion for Czech beer! Cheers! 🍻

\~FREE EVENT\~ Meet Locals & internationals People Every Tuesday & Make New Friends🙂 For introverts and shy people (we all are sometimes), we have ice-breaking games and more... so feel free to come by. Everyone is invited to enjoy amazing Cocktails in 135kc only🍸 Beer in 49 kc 🥂🍻 It is organized after our Biggest Event in Central Europe with 234 people in a single event. 🙂 📍LOCATION TEQUILA TALES BAR & MUSIC CLUB Újezd 409/19, 118 00 Malá Strana, 118 00 Prague, Czech Republic (Nearest tram stop- Hellichova & Ujezd) ❓Questions❓ Follow & write to https://www.instagram.com/tequilatales_prg/ *** \~AKCE ZDARMA\~ Každé úterý se seznamte s místními a mezinárodními lidmi a najděte si nové přátele🙂 Pro introverty a stydlivé lidi (všichni jsme někdy) máme hry na lámání ledu a další... tak neváhejte a přijďte. Všichni jsou zváni k vychutnání úžasných koktejlů jen za 135 kč🍸 Pivo za 49 kč 🥂🍻 Je pořádána po naší největší akci ve střední Evropě s 234 lidmi na jediné akci. 🙂 📍 POLOHA TEQUILA TALES BAR & MUSIC CLUB Újezd 409/19, 118 00 Malá Strana, 118 00 Praha, Česká republika (nejbližší tramvajová zastávka- Hellichova & Újezd) ❓Otázky❓ Sledujte a pište https://www.instagram.com/tequilatales_prg/

From one of the masters of contemporary American magical realism, this story is a highly original and surprising tale of a man visiting an old friend and his surprise at who (or what) he finds out his new wife is. We will meet and discuss our reactions/interpretations. The story is too new to have a free versions online but I will provide a pdf access in a few days. You can listen to the story [here](https://podcasts.apple.com/cz/podcast/richard-powers-reads-steven-millhauser/id256945396?i=1000379551486) plus it includes some discussion.

**Talks:** *Cyber ​​Resilience Act and Open-Source* *by* *Kayla Eilhart* * how the CRA was created and what it is for * how we almost lost open-source * what the CRA and related legislation and regulation introduce in connection with open-source * what further legislation and regulation related to the functioning of open-source in the EU awaits us * links to information, working groups and how to participate in the legislative process **Schedule** **18:30** – Doors open **19:00** – Talk “*Cyber ​​Resilience Act and Open-Source*” 19:45 – Lightning talks: add yours to [https://bit.ly/prpylight](https://bit.ly/prpylight) after 20:00 – Networking **Good to know** * You don’t have to register for this meetup – the actual attendance is much bigger (40–70 Pythonistas) than indicated in the “Going” list here. * **Cash only payments – club doesn’t accept cards.** * Talks at Pyvo are mostly in Czech but it there’s somebody who doesn’t understand Czech talks are switched to English if the speaker is able to do so. * Besides both soft drinks and beer it's possible to eat at the club. Choice is variable and consists of 4 to 7 options ranging from toast, sausages and soup to fried cheese in a bun, goulash or schnitzel. * Club closes at midnight.

Abstract: I'm tired to see ground that could be used for heirloom turnips (they grow better in cold and you can hardly see them in shops, there are courgettes and tomatoes in winter and spring instead..) trees and bushes being used exclusively for grass instead. Mushrooms can be grown easily and safely outdoors in wooden logs.. Some parks in several cities specially abroad but also in Czech Rep. and areas elsewhere seem to want to imitate those that were imitating Victorian times: lush huge lawns. Do we all really like grandeur without a trace of food gardens, and because that's how it's done it has to be this way? People would not take care and give continuity to small initiatives, many have been there done that. But isn't it the fault of the organization always? I think so. People like the idea of thinking outside of the box, [while being] inside the box. That just doesn't really work very well. So this is an invite, for each other to be able to know what might appeal to others in the framework of finding spaces to grow food to not need to rely so much on what one sees in the shops. 🌿🌿

Join ProductTank Prague at the first product meetup of the new year! 🎉(Happy New Year!) We’ll take a deep dive into the world of AI. You can expect three (to be revealed soon) speakers who will share real-world use cases of AI across the product lifecycle. ⚠️ **Save your spot now — capacity is limited!** **Date & Location** 🗓️ February 19, 2026 📍 Gen Office, Pikrtova 1737/1a, 140 00 Prague 4 – Nusle 🗂️ **Agenda** **17:30** – Doors Open **18:00** – Welcome & Intro **18:10** – **Diana Prokusheva** Our failures with LLMs in UXR: LLMs can't replace real users or interviews, but they excel at preparation and review. They empower us from pre-testing interviews, scripts, and surveys to usability audits and competitive benchmarking. **18:40** – **Anton Smirnov** AI evals are becoming a must-have PM skill, yet they’re often buried under buzzwords. They don’t have to be complex frameworks. When used right, they enable real product impact from day one, from clearer decisions to better AI quality. **19:10** – 10-minute break 🍕 **19:20 -** Speaker 3 (To be announced soon.) **19:40** – Networking **22:00** – End of meetup

This meetup is part of the **Road to ETHPrague** series and is organized in collaboration with [Ackee Blockchain Security](https://ackee.xyz/). Register to the event via this link: [https://luma.com/z4ovo5n7](https://luma.com/z4ovo5n7) ​​​​📅 **Date: 19.2. 2026** 📍 **Location:** [Rohanské nábř. 717, 186 00 Karlín](https://www.google.com/maps/place//data=!4m2!3m1!1s0x470b953acbb76d2f:0xdc5905af08d2dd87?sa=X&ved=1t:8290&ictx=111) 🕰️ **Time:** 18:00–21:00 ## ​**​​​Agenda & Speakers** ​18:00 - 18:15 Welcome ​18:30 - 19:00 Culture clash: Ethereum vs Solana (Josef Gattermayer, Ackee Blockchain Security) ​19:00 - 19:30 Solana community in Prague (Sven, Solana CZ community) ​19:30 - 20:00 Wake Arena & Trident Arena: Multi-agent AI audits (Josef Bazal, Ackee Blockchain Security) ​20:00 - 20:30 Brainstorming session: Shaping the ETHPrague Speaker Line-Up ​20:30 - 21:00 Networking ​​​​⚠️ **Disclaimer:** Photos will be taken during the event. If you prefer not to be photographed, please let us known.

Dear all I would like to invite you to visit together the exhibition: Body Worlds. More info can be found at the link here below : https://www.bodyworlds.cz/en/vystava **Exhibition Overview** BODY WORLDS is an international exhibition featuring real human bodies and organs preserved through the plastination technique, a process developed by German anatomist Dr. Gunther von Hagens. Plastination allows the human body to be displayed in lasting, three-dimensional form, revealing anatomy, movement, and internal systems with exceptional clarity.The exhibition continues a long dialogue between anatomy and art, echoing the anatomical studies of Leonardo da Vinci, Michelangelo, and Vesalius, as well as artistic reflections such as Rembrandt’s The Anatomy Lesson. BODY WORLDS places the human body at the intersection of medical knowledge and visual culture, inviting viewers to see anatomy as both scientific subject and artistic form. meeting point : Main entrance Westfield Chodov shopping center: [Roztylska 2321/19,](https://www.google.com/maps/place//data=!4m2!3m1!1s0x470b9232c2d3f475:0x9f039cb6c612bafe?sa=X&ved=1t:8290&ictx=111) [Prague 11-Chodov](https://www.google.com/maps/place//data=!4m2!3m1!1s0x470b9232c2d3f475:0x9f039cb6c612bafe?sa=X&ved=1t:8290&ictx=111) [148 00](https://www.google.com/maps/place//data=!4m2!3m1!1s0x470b9232c2d3f475:0x9f039cb6c612bafe?sa=X&ved=1t:8290&ictx=111) 22nd Feb 15:30 PM short agenda: introduction project; ice breaker visit of the exhibition sharing impressions coffee optional ( for those willing to socialize more after the exhibition) estimated duration: approximately 3 hours admission cost : 390 CZK full / adults if you can't find the group phone at : 00420770171095 I look forward to meeting you ps please do not accept if you are not sure to come and give the opportunity for others to join

Step into a real-life fairytale! Join us for a magical day trip to Český Krumlov — a UNESCO World Heritage town and one of the most picturesque places in Europe. With its cobbled streets, colourful houses, riverside views, and a castle perched above it all, this destination feels like stepping back in time. Český Krumlov dates back to the 13th century and grew around its stunning castle, which is one of the largest in Central Europe. The town is wrapped by the Vltava River, creating amazing viewpoints, hidden corners, and perfect photo spots. From medieval streets to lively cafés, it’s the kind of place where you just wander and discover something new at every turn. Expect history, great views, chill exploration, and lots of good memories — all in one day. Whether you’re into sightseeing, photography, or just soaking up the atmosphere, this trip has something for everyone. Distance : 10 km (aprox. 6 hours) Difficulty Rating : Easy to Moderate Tour Highlights: • Hassle-free day trip to Český Krumlov from Prague • Professional and friendly guide • Transportation by air-conditioned bus • Český Krumlov Castle & Castle Complex • Castle Tower (tour) • Old Town (Historic Center) • Latrán Street (One of the oldest streets in the city) • Cloak Bridge (Plášťový most) More information at : https://www.facebook.com/events/2035605153885492/

We are a group of runners who meet most weeks for a run around the beautiful Vltava River's edge. You can bring your running shoes straight from the office/home office if you don't have time to stop at home. There will be a place to put your bags in the Cafe. We will run about 9 km along the river and have a drink afterwards. Paces vary! We will meet in the square near Kavarna Liberal (Hermanova 6), near the Vltavska metro/tram stop at 6:30 on Wednesday. See you there!

**New Dojo Location!** **Draft Day Columbus** 1130 Dublin Road Columbus, OH 43215 We're going to try a new dojo location for a few weeks and see how it works Dojos are informal Python group study sessions where everyone interested in Python gathers to learn about Python, help others with Python, or just hang out. Everyone is welcome from Python beginners to experts. Bringing a laptop is encouraged (we'll have extension cords and power strips). If there's something you want to learn leave a comment on this invite so we can plan ahead. We're looking for topic suggestions and people interested in presenting at our monthly meetings. To this end we've set up a survey form at [https://docs.google.com/forms/d/15eBKF1nQQ2XS5gzD4rvhVRHMBEj7lJtHuA9wXupS3Uc](https://docs.google.com/forms/d/15eBKF1nQQ2XS5gzD4rvhVRHMBEj7lJtHuA9wXupS3Uc)

**NEW LOCATION: Improving Office in Franklinton** Physical location: Improving Office 330 Rush Alley Suite #150 Columbus, OH 43215 Schedule: * 6:00 p.m.: Socialize, eat, and drink. Improving will be providing pizza and beverages. * 6:30 to 8:00 pm. Main meeting and presentation(s). See the handy Parking Map - we recommend street parking. [Street Parking Map](https://docs.google.com/presentation/d/1u2A4fLNlxwLJn0KA_hKc8bnFlFHLvsHBDh-_8wzX_tk/edit?usp=sharing) We meet on the last Monday of each Month. Presentations are given by members and friends of this group. If you would like to do a presentation (small or large) on a python topic, please contact centralohpython@gmail.com

Join the Columbus AI community for our quarterly gathering — a casual, community-focused evening where everyone has a chance to share, learn, and connect. These open mic–style events give anyone in the community up to **5 minutes** to present a project, share a tool, pose a question, or offer a perspective on the evolving AI space. No slides required — just a welcoming space to exchange ideas and keep the local AI conversation moving. If you’d like to take the stage, message **Chris (the organizer)** with a **title and short description** of what you’d like to share. Whether you’re deep in the field or just getting curious, come connect with others building and exploring AI in Columbus. Sponsored by [Transform Labs](https://www.transformlabs.com/services)

Join Neurospicy Columbus at the Stauff's for coffee and then a stroll through the Book Loft nearby! This will be a friendly chat for like minded individuals with Autism and/or ADHD (or somewhere on the Neurodiverse Spectra).

**Important time note:** Please plan on arriving between 5:30 and 6:00 as the elevators lock after 6 and you'll need to message us and we'll need to come get you. The building address is 4450 Bridge Park The entrance is 6620 Mooney St, Suite 400 You will need to scan your ID at the door to get a visitor badge. **Abstract** *Spec-Driven Development with GitHub Spec-Kit: From Intent to Implementation* Spec-driven development flips the traditional workflow on its head: instead of code being the source of truth, the specification becomes the backbone of design, collaboration, and delivery. In this session, we’ll explore how GitHub Spec-Kit enables teams to treat specifications as first-class artifacts—living documents that drive architecture, implementation, and verification. You’ll learn how Spec-Kit helps teams clearly express intent using structured, version-controlled specs that live alongside code. We’ll walk through a practical workflow that starts with defining system behavior and constraints, then progressively refines those specs into testable, automatable outcomes. Along the way, we’ll show how specs can reduce ambiguity, improve cross-functional collaboration, and make design decisions explicit before a single line of production code is written. This talk will cover: --What spec-driven development is (and what it isn’t) --How GitHub Spec-Kit fits into modern developer workflows --Using specs to align product, engineering, and AI-assisted development --Real-world examples of turning specs into implementations with confidence Whether you’re building greenfield systems, integrating AI into your stack, or trying to reduce costly rework, spec-driven development offers a scalable way to move faster without sacrificing clarity. Attendees will leave with concrete patterns and a clear mental model for adopting GitHub Spec-Kit in their own projects. **YouTube Link** TBA

**Understanding the Columbus Housing Market: Let’s Talk Downsizing for Seniors** Understanding the Market to Make Your Best Move Yet Thinking about downsizing or helping a parent prepare for a move? Join us for a friendly, educational seminar designed specifically for seniors in Central Ohio. We’ll break down what’s happening in today’s Columbus housing market, explore timing and planning for downsizing, and discuss easy ways to prepare a longtime home for sale—without overwhelm. You’ll also learn about low‑maintenance housing options, financial considerations, and simple steps to make your next move smooth and stress‑free. This is a relaxed, no‑pressure event where you can ask questions and get practical advice tailored to seniors and their families. Hosted by: Katie McCartney, Broker & Senior Real Estate Specialist® (SRES)

Want to be a speaker? submit your talk to our Call for Presenters!!! https://sessionize.com/cbus-hug-2026/