BioInformatics

**Latest Dojo Location!** **Knotty Pine Brewing** 1765 W 3rd Ave, Columbus, OH 43212 We're going to try a new dojo location for a few weeks and see how it works Dojos are informal Python group study sessions where everyone interested in Python gathers to learn about Python, help others with Python, or just hang out. Everyone is welcome from Python beginners to experts. Bringing a laptop is encouraged (we'll have extension cords and power strips). If there's something you want to learn leave a comment on this invite so we can plan ahead. We're looking for speakers for our Monthly Meetups! Fill out the form if you are interested in presenting to the Python Community. https://forms.gle/ehSfUAC2WgR34Crq9

Highlights and Hidden Gems in SQL Server 2025 With so much emphasis on cloud data platforms and AI these days, SQL people can feel left behind by all the marketing hype. SQL Server 2025 was officially released in November of 2025, though, and contains a ton of improvements that will make our SQL Server deployments a bit faster, better, and more secure. There are even more improvements tucked into the release that never made a marketing blog or press release that you'll likely be learning about for the first time in this session! Join this session to learn about what makes your high availability a little more available, your performance a bit more performant, and your database more developer and app-friendly. Come spend an hour with SQL people talking SQL Server 2025 – the good, the "not quite ready for prime time", and the hidden awesomeness.

Most people use LLMs by feel: ask a question, read the answer, decide whether it “seems good,” and move on. That works for casual use. It does not work when you are building software, automating workflows, writing important documents, or relying on AI for anything that needs to be repeatable. In this talk, we’ll look at how to improve and evaluate the inputs and outputs of LLMs using practical measurement techniques. We’ll cover how prompt changes affect results, how to compare outputs, how to build simple evaluation sets, and how math-based methods like similarity scoring can help you move beyond guesswork. This will be beginner-friendly, so even if you don't know anything about AI, you should get something out of it. However, this will be a little more technical than our intro talks. You do not need to be an AI researcher, but programmers and technically curious attendees will get a lot out of it. We’ll cover: * Why “it looks good” is not enough * How to improve prompts by changing the input, context, and constraints * How to compare LLM outputs more systematically * Basic evaluation techniques for accuracy, consistency, and usefulness * How embeddings, cosine similarity, and scoring can help evaluate results * Where automated evaluation works — and where humans still need to stay in the loop By the end, you’ll have a practical mental model for treating LLMs less like magic and more like systems you can test, measure, and improve. LOGISTICS AND PARKING: The talk starts at 7:00 PM. The first half hour is reserved for everyone to get set up and mingle. Free pizza and drinks! The cheapest parking option is to find street parking, which will only cost you a few bucks. Otherwise, park in the nearby veteran's museum lot for $8. It's highly recommended you avoid the nearby $15 garage parking.

Join Katie McCartney, SRES®, for a straightforward update on the 2026 Central Ohio housing market and its impact on seniors and their families. Whether you plan to buy, sell, right-size, assist a parent, or understand the current market, this session provides reliable insights in a supportive environment. In this complimentary class, Katie will explain trends affecting home buying and selling for older adults in Central Ohio, outline realistic expectations for 2026, and answer your questions in an open Q&A. This supportive, information-focused workshop is designed to provide clarity and confidence with no sales pitch. Ideal for: * Seniors considering selling their current home or purchasing a better‑fit property * Adult children helping parents navigate a home sale or move * Anyone seeking a calm, trustworthy source of information about today's real estate market What You Will Learn: * A senior‑friendly look at the 2026 Central Ohio housing market for buyers and sellers * What to expect when selling a longtime home or purchasing your next one * Personalized answers during an open Q&A You will leave with a clearer understanding of your options and practical steps to move forward with confidence. *** **Hosted by:** **Katie McCartney, Broker & Senior Real Estate Specialist® (SRES) with** Pillar Realty, LLC Compassionate guidance for seniors navigating housing transitions in Central Ohio. *** **Location:** Columbus Metropolitan Library: Dublin Branch 75 N High St, Dublin, OH 43017 ([https://maps.app.goo.gl/GL2vbJgUHqTncbHZ9](https://maps.app.goo.gl/GL2vbJgUHqTncbHZ9)) Meeting Room 2 **Doors Open:** 1 PM **Seats:** Limited Seating (first come, first served) **Cost:** Complimentary

Want to be a speaker? submit your talk to our Call for Presenters!!! https://sessionize.com/azure-cbus-2026/

We have moved to guild.host. Look us up there. https://guild.host/events/buckeye-cocoaheads-rcavwd

You can sleep in on the Sesquicentennial (observed), we’re shifting to the following Friday. But join the local UX community for a chat and some biscuits to catch up. If you were in CA for Figma Config, tell us all the lines and you can tell me how I can animate an SVG without coding it by hand, and why I’d even want to. Thanks to the team at Nationwide of supporting the group.