Innovations in ddPCR and Genomic Analytics (S1E3)

Join us for the next EPPIC Meetup, where we explore the convergence of molecular diagnostics and AI-driven data platforms shaping the future of precision medicine. This event will spotlight two transformative applications: one in droplet digital PCR (ddPCR) and the other in multimodal data analysis for generative AI applications.
Whether you're a molecular biologist, data scientist, or healthcare innovator, this is the perfect opportunity to connect, learn, and be inspired.

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## 1. Molecular Precision Meets Machine Intelligence: The Future of ddPCR

Speaker: Dr. Séverine Margeridon, PhD, PMP
Title: Associate Director, Assay Development, Molecular Diagnostics
Organization: Bio-Rad Laboratories
Dr. Margeridon will delve into the integration of droplet digital PCR (ddPCR) with machine intelligence to enhance molecular diagnostics. She will discuss recent advancements in high-multiplex methylation-sensitive ddPCR assays, particularly for non-invasive prenatal testing (NIPT). These innovations aim to improve the accuracy and efficiency of fetal fraction estimation in cell-free DNA (cfDNA) samples, offering a faster and more cost-effective alternative to traditional methods.

### 2. PrimateAI-3D - Primate Genome Aggregation Database

Speaker: Hong Gao, PhD
Title: Associate Principal Bioinformatics Scientist
Organization: Illumina
Dr. Gao will talk about the Primate Genome Aggregation Database, a publicly available resource cataloguing ~4.3 million common missense variants across 233 non‑human primate species—over 50× the size of ClinVar’s benign variant set. These primate-derived variants are confirmed benign in >99% of human cases, providing a powerful filter to distinguish neutral from pathogenic human missense mutations. By integrating this database into PrimateAI‑3D, Illumina’s team enabled a 73% increase in gene–phenotype associations in UK Biobank rare-variant analyses

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## Agenda

5:00 – 6:00 PM: Check-in & Networking
6:00 – 7:30 PM: Welcome, Presentations & Q&A
7:30 – 8:30 PM: Continued Networking
Light refreshments will be provided.

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## Venue

Location: Persistent Systems Inc
Address: 2055 Laurelwood Rd, Santa Clara, CA 95054

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## Who Should Attend?

• Bioinformaticians
• Computational biologists
• Data scientists in biopharma and healthcare
• Healthcare professionals and technologists interested in AI/ML applications

If you're excited about how machine learning and data platforms are transforming healthcare and research, you won’t want to miss this.

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Acknowledgment:
Special thanks to Persistent Systems for generously sponsoring this event and providing their venue, reflecting their commitment to innovation and community engagement.

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About Our Sponsor:
Persistent Systems (BSE & NSE: PERSISTENT) is a global leader in digital engineering and enterprise modernization services, offering expertise across AI-enabled software engineering, product development, data analytics, cloud computing, CX transformation, and intelligent automation. With a commitment to sustainability, Persistent is carbon neutral and included in major global indices, demonstrating a robust commitment to responsible business practices and innovation. Learn more at www.persistent.com.

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## Want to Get Involved?

• Have an AI/ML use case or product to showcase?
• Interested in sponsoring, hosting, or helping organize future meetups?
• Just love geeking out about AI in healthcare?

We'd love to hear from you! Reach out at [admin@eppicglobal.org](mailto:admin@eppicglobal.org).

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## About EPPIC Global

EPPIC Global is a cross-disciplinary network bringing together healthcare professionals, scientists, technologists, and entrepreneurs. From early discovery to clinical application, our community is united by a shared mission: driving innovation to create better healthcare outcomes.
We organize events, mentorship programs, and our flagship EPPICon conference—helping bridge the worlds of technology and medicine through connection, collaboration, and visionary thinking.