San Francisco AI and Machine Learning Meetup Group

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Vision-Driven Behavior Analysis in Autism: Challenges and Opportunities

Understanding and classifying human behaviors is a long-standing goal at the intersection of computer science and behavioral science. Video-based monitoring provides a non-intrusive and scalable framework for analyzing complex behavioral patterns in real-world environments. This talk explores key challenges and emerging opportunities in AI-driven behavior analysis for individuals with autism spectrum disorder (ASD), with an emphasis on the role of computer vision in building clinically meaningful and interpretable tools.

About the Speaker

Somaieh Amraee is a postdoctoral research fellow at Northeastern University’s Institute for Experiential AI. She earned her Ph.D. in Computer Engineering and her research focuses on advancing computer vision techniques to support health and medical applications, particularly in children’s health and development.

PRISM: High-Resolution & Precise Counterfactual Medical Image Generation using Language-guided Stable Diffusion

PRISM, an explainability framework that leverages language-guided Stable Diffusion that generates high-resolution (512×512) counterfactual medical images with unprecedented precision, answering the question: “What would this patient image look like if a specific attribute is changed?” PRISM enables fine-grained control over image edits, allowing us to selectively add or remove disease-related image features as well as complex medical support devices (such as pacemakers) while preserving the rest of the image. Beyond generating high-quality images, we demonstrate that PRISM’s class counterfactuals can enhance downstream model performance by isolating disease-specific features from spurious ones — a significant advancement toward robust and trustworthy AI in healthcare.

About the Speaker

Amar Kumar is a PhD Candidate at McGill University | MILA Quebec AI Institute in the Probabilistic Vision Group (PVG). His research primarily focuses on generative AI and medical imaging, with the main objective to tackle real-world challenges like bias mitigation in deep learning models.

Building Your Medical Digital Twin — How Accurate Are LLMs Today?

We all hear about the dream of a digital twin: AI systems combining your blood tests, MRI scans, smartwatch data, and genetics to track health and plan care. But how accurate are today’s top tools like GPT-4o, Gemini, MedLLaMA, or OpenBioLLM — and what can you realistically feed them?

In this talk, we’ll explore where these models deliver, where they fall short, and what I learned testing them on my own health records.

About the Speaker

Ekaterina Kondrateva is a senior computer vision engineer with 8 years of experience in AI for healthcare, author of 20+ scientific papers, and finalist in three international MRI analysis competitions. Former head of AI research for medical imaging at HealthTech startup LightBC.

Deep Dive: Google’s MedGemma, NVIDIA’s VISTA-3D and MedSAM-2 Medical Imaging Models

In this talk, we’ll explore three medical imaging models. First, we’ll look at Google’s MedGemma open models for medical text and image comprehension, built on Gemma 3. Next,, we’ll dive into NVIDIA’s Versatile Imaging SegmenTation and Annotation (VISTA) model which combines semantic segmentation with interactivity, offering high accuracy and adaptability across diverse anatomical areas for medical imaging. Finally, we’ll explore MedSAM-2, an advanced segmentation model that utilizes Meta’s SAM 2 framework to address both 2D and 3D medical image segmentation tasks.

About the Speaker

Daniel Gural is a seasoned Machine Learning Engineer at Voxel51 with a strong passion for empowering Data Scientists and ML Engineers to unlock the full potential of their data.

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Multimodal AI for Efficient Medical Imaging Dataset Curation

We present a multimodal AI pipeline to streamline patient selection and quality assessment for radiology AI development. Our system evaluates patient clinical histories, imaging protocols, and data quality, embedding results into imaging metadata. Using FiftyOne researchers can rapidly filter and assemble high-quality cohorts in minutes instead of weeks, freeing radiologists for clinical work and accelerating AI tool development.

About the Speaker

Brandon Konkel is a Senior Machine Learning engineer at Booz Allen Hamilton with over a decade of experience developing AI solutions for medical imaging.

AI-Powered Heart Ultrasound: From Model Training to Real-Time App Deployment

We have built AI-driven tools to automate the assessment of key heart parameters from point-of-care ultrasound, including Right Atrial Pressure (RAP) and Ejection Fraction (EF). In collaboration with UCSF, we trained deep learning models on a proprietary dataset of over 15,000 labeled ultrasound studies and deployed the full pipeline in a real-time iOS app integrated with the Butterfly probe. A UCSF-led clinical trial has validated the RAP workflow, and we are actively expanding the system to support EF prediction using both A4C and PLAX views.

This talk will present our end-to-end pipeline, from dataset development and model training to mobile deployment—demonstrating how AI can enable real-time heart assessments directly at the point of care.

About the Speaker

Jeffrey Gao is a PhD candidate at Caltech, working at the intersection of machine learning and medical imaging. His research focuses on developing clinically deployable AI systems for ultrasound-based heart assessments, with an emphasis on real-time, edge-based inference and system integration.

Let’s Look Deep at Continuous Patient Monitoring

In hospitals, direct patient observation is limited–nurses spend only 37% of their shift engaged in patient care, and physicians average just 10 visits per hospital stay. LookDeep Health’s AI-driven platform enables continuous and passive monitoring of individual patients, and has been deployed “in the wild” for nearly 3 years. They recently published a study validating this system, titled “Continuous Patient Monitoring with AI”. This talk is a technical dive into said paper, focusing on the intersection of AI and real-world application.

About the Speaker

Paolo Gabriel, PhD is a senior AI engineer at LookDeep Health, where they continue to use computer vision and signal processing to augment patient care in the hospital.

AI in Healthcare: Lessons from Oncology Innovation

About the Speaker

Artificial intelligence is rapidly transforming how we diagnose, treat, and manage health.

Dr. Asba (AT) Tasneem is a healthcare data and innovation leader with over 20 years of experience at the intersection of clinical research, AI, and digital health. She has led large-scale programs in oncology and data strategy, partnering with organizations like the FDA, Duke University, and top pharma companies to drive AI-enabled healthcare solutions.

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MedVAE: Efficient Automated Interpretation of Medical Images with Large-Scale Generalizable Autoencoders

We present MedVAE, a family of six generalizable 2D and 3D variational autoencoders trained on over one million images from 19 open-source medical imaging datasets using a novel two-stage training strategy. MedVAE downsizes high-dimensional medical images into compact latent representations, reducing storage by up to 512× and accelerating downstream tasks by up to 70× while preserving clinically relevant features. We demonstrate across 20 evaluation tasks that these latent representations can replace high-resolution images in computer-aided diagnosis pipelines without compromising performance. MedVAE is open-source with a streamlined finetuning pipeline and inference engine, enabling scalable model development in resource-constrained medical imaging settings.

About the Speakers

Ashwin Kumar is a PhD Candidate in Biomedical Physics at Stanford University, advised by Akshay Chaudhari and Greg Zaharchuk. He focuses on developing deep learning methodologies to advance medical image acquisition and analysis.

Maya Varma is a PhD student in computer science at Stanford University. Her research focuses on the development of artificial intelligence methods for addressing healthcare challenges, with a particular focus on medical imaging applications.

Leveraging Foundation Models for Pathology: Progress and Pitfalls

How do you train ML models on pathology slides that are thousands of times larger than standard images? Foundation models offer a breakthrough approach to these gigapixel-scale challenges. This talk explores how self-supervised foundation models trained on broad histopathology datasets are transforming computational pathology. We’ll examine their progress in handling weakly-supervised learning, managing tissue preparation variations, and enabling rapid prototyping with minimal labeled examples. However, significant challenges remain: increasing computational demands, the potential for bias, and questions about generalizability across diverse populations. This talk will offer a balanced perspective to help separate foundation model hype from genuine clinical value.

About the Speaker

Heather D. Couture is a consultant and founder of Pixel Scientia Labs, where she partners with mission-driven founders and R&D teams to support applications of computer vision for people and planetary health. She has a PhD in Computer Science and has published in top-tier computer vision and medical imaging venues. She hosts the Impact AI Podcast and writes regularly on LinkedIn, for her newsletter Computer Vision Insights, and for a variety of other publications.

LesionLocator: Zero-Shot Universal Tumor Segmentation and Tracking in 3D Whole-Body Imaging

Recent advances in promptable segmentation have transformed medical imaging workflows, yet most existing models are constrained to static 2D or 3D applications. This talk presents LesionLocator, the first end-to-end framework for universal 4D lesion segmentation and tracking using dense spatial prompts. The system enables zero-shot tumor analysis across whole-body 3D scans and multiple timepoints, propagating a single user prompt through longitudinal follow-ups to segment and track lesion progression. Trained on over 23,000 annotated scans and supplemented with a synthetic time-series dataset, LesionLocator achieves human-level performance in segmentation and outperforms state-of-the-art baselines in longitudinal tracking tasks. The presentation also highlights advances in 3D interactive segmentation, including our open-set tool nnInteractive, showing how spatial prompting can scale from user-guided interaction to clinical-grade automation.

About the Speaker

Maximilian Rokussis is a PhD scholar at the German Cancer Research Center (DKFZ), working in the Division of Medical Image Computing under Klaus Maier-Hein. He focuses on 3D multimodal and multi-timepoint segmentation with spatial and text prompts. With several MICCAI challenge wins and first-author publications at CVPR and MICCAI, he co-leads the Helmholtz Medical Foundation Model initiative and develops AI solutions at the interface of research and clinical radiology.

LLMs for Smarter Diagnosis: Unlocking the Future of AI in Healthcare

Large Language Models are rapidly transforming the healthcare landscape. In this talk, I will explore how LLMs like GPT-4 and DeepSeek-R1 are being used to support disease diagnosis, predict chronic conditions, and assist medical professionals without relying on sensitive patient data. Drawing from my published research and real-world applications, I’ll discuss the technical challenges, ethical considerations, and the future potential of integrating LLMs in clinical settings. The talk will offer valuable insights for developers, researchers, and healthcare innovators interested in applying AI responsibly and effectively.

About the Speaker

Gaurav K Gupta graduated from Youngstown State University, Bachelor’s in Computer Science and Mathematics.

Where
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What Foundation Models really need to be capable of for Autonomous Driving – The Drive4C Benchmark

Foundation models hold the potential to generalize the driving task and support language-based interaction in autonomous driving. However, they continue to struggle with specific reasoning tasks essential for robotic navigation. Current benchmarks typically provide only aggregate performance scores, making it difficult to assess the underlying capabilities these models require. Drive4C addresses this gap by introducing a closed-loop benchmark that evaluates semantic, spatial, temporal, and physical understanding—enabling more targeted improvements to advance foundation models for autonomous driving.

About the Speaker

Tin Stribor Sohn is a PhD Student at Porsche AG and Karlsruhe Institute of Technology in the area of Foundation Models for Scenario Understanding and Decision Making in Autonomous Robotics, Tech Lead at Data Driven Engineering for Autonomous Driving, Prior: Master in CS at University of Tuebingen with focus on Computer Vision and Deep Learning and co-founder of a software company for smart EV charging.

Human Motion Prediction – Enhanced Realism via Nonisotropic Gaussian Diffusion

Predicting future human motion is a key challenge in generative AI and computer vision, as generated motions should be realistic and diverse at the same time. This talk presents a novel approach that leverages top-performing latent generative diffusion models with a novel paradigm. Nonisotropic Gaussian diffusion leads to better performance, fewer parameters, and faster training at no additional computational cost. We will also discuss how such benefits can be obtained in other application domains.

About the Speaker

Cecilia Curreli is a Ph.D. student at the Technical University of Munich, specializing in generative models. A member of the AI Competence Center at MCML, she has conducted research in deep learning, computer vision, and quantum physics through international collaborations with the University of Tokyo and the Chinese Academy of Science.

Efficient Few-Shot Adaptation of Open-Set Detection Models

We propose an efficient few-shot adaptation method for the Grounding-DINO open-set object detection model, designed to improve performance on domain-specific specialized datasets like agriculture, where extensive annotation is costly. The method circumvents the challenges of manual text prompt engineering by removing the standard text encoder and instead introduces randomly initialized, trainable text embeddings. These embeddings are optimized directly from a few labeled images, allowing the model to quickly adapt to new domains and object classes with minimal data. This approach demonstrates superior performance over zero-shot methods and competes favorably with other few-shot techniques, offering a promising solution for rapid model specialization.

About the Speaker

Dr. Sudhir Sornapudi is a Senior Data Scientist- II at Corteva Agriscience. He leads the Advanced Vision Intelligence team, driving computer vision innovations internally from cell-to-space with Biotechnology, Crop Health, and Seed Operations.

OpticalNet: An Optical Imaging Dataset and Benchmark Beyond the Diffraction Limit

Optical imaging capable of resolving nanoscale features would revolutionize scientific research and engineering applications across biomedicine, smart manufacturing, and semiconductor quality control. However, due to the physical phenomenon of diffraction, the optical resolution is limited to approximately half the wavelength of light, which impedes the observation of subwavelength objects such as the native state coronavirus, typically smaller than 200 nm. Fortunately, deep learning methods have shown remarkable potential in uncovering underlying patterns within data, promising to overcome the diffraction limit by revealing the mapping pattern between diffraction images and their corresponding ground truth object images.

However, the absence of suitable datasets has hindered progress in this field —— collecting high-quality optical data of subwavelength objects is highly difficult as these objects are inherently invisible under conventional microscopy, making it impossible to perform standard visual calibration and drift correction. Therefore, we provide the first general optical imaging dataset based on the “building block” concept for challenging the diffraction limit. Drawing an analogy to modular construction principles, we construct a comprehensive optical imaging dataset comprising subwavelength fundamental elements, i.e., small square units that can be assembled into larger and more complex objects. We then frame the task as an image-to-image translation task and evaluate various vision methods. Experimental results validate our “building block” concept, demonstrating that models trained on basic square units can effectively generalize to realistic, more complex unseen objects. Most importantly, by highlighting this underexplored AI-for-science area and its potential, we aspire to advance optical science by fostering collaboration with the vision and machine learning communities.

About the Speakers

Wang Benquan is the final-year PhD candidate at Nanyang Technological University, Singapore. His research interests are AI for Science, scientific deep learning, optical metrology and imaging.

Ruyi is a PhD at University of Texas at Austin, working on generative models and reinforcement learning, and their applications.