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What Is Progress? Knowledge Aggregation, Living Textbooks, and the Automation
Title: What Is Progress? Knowledge Aggregation, Living Textbooks, and the Automation of Scientific Discovery
Date: June 20 2026 Noon - 14:00 EDT
Summary: Our collective knowledge infrastructure — the textbooks, professional training resources, and literature syntheses that define what professionals across disciplines believe to be true — is quietly accruing a structural liability. Compounded confirmation bias, stacked citation-by-citation into the foundations of formal knowledge, means that breakthroughs can take decades to reach the classrooms, clinical workflows, and decision-making frameworks where they matter most. Meanwhile, the deepest friction is rarely acknowledged: before any field can build meaningful consensus on "why" or "how" a phenomenon occurs, it must first establish honest, consolidated agreement on "what" has actually been observed. That prior step is routinely skipped, assumed, or fragmented across siloed literatures that never cross-pollinate.
This talk introduces a framework called "Knowledge Aggregation" — with two distinct but complementary ambitions. The first is descriptive transparency: algorithmically mapping what has been said, measured, and documented across a problem space, without imposing causal interpretation or narrative. The second traces the boundary between empirical observation and explanatory claim, building systems that can separate the "what" from the "why/how" — because consensus on mechanism cannot be meaningfully constructed until consensus on phenomenon is first established.
Both ambitions are now within reach. By composing tools already at our disposal — large language models, classical NLP pipelines, public data repositories, and engineering-grade automation frameworks — it becomes possible to model knowledge itself, rather than merely imitate individual experts. One concrete expression of this is automating the writing of living textbooks: compressing the lag from bleeding-edge discovery, through replicated evidence, all the way to professional training resources. But the deeper aspiration reaches further — toward automating the discovery of scientific insights that have never previously been conceived, by systematically surfacing hypothesis combinations that no single siloed researcher would have had the cross-disciplinary vantage point to even ask. Drawing on ongoing systems biology and computational research — with ME/CFS research demoed as a use case for what siloed, fragmented knowledge infrastructure costs in practice — this talk maps the conceptual architecture, the real-world friction, and the data science toolkit for building it.
Speaker: As a systems biologist at heart, Sam specializes his biomedical research on interactions and connections in biology - rather than just one domain of expertise. He wears many hats and collects skill sets across disciplines, with degree studies and industry experience acquired across Chemical Engineering (BSc), Bioinformatics (MSc), Systems and Synthetic Biology (M2), Biomedical Sciences (MSc), and beyond. Even more important to him than niches or fields of work, comes down to the synergistic approaches that allow us to move beyond reductionism. The notion that a question can only allow for one answer, is inherently reductionist. By resisting many norms in science and engineering which can get overly reductive, his current role as Principal Investigator of Research for DMV Petri Dish (501(c)(3) non-profit local to the DMV region) embraces computational frameworks that aide scale-up and automation - not only around the processes which already exist with established workflows, but also taking a keen interest in attempting and accomplishing ambitions which have never been perceived to be possible previously. Sam carries a passion for the synergy of computational biology - fused with wet lab validation. This way, one can build a beautiful knowledge base in the theoretical sense, and then test to see if said computational prediction might actually be able to stand in the real world with wet lab validation. Translational modeling starts to become possible once biological experiment design can be iteratively looped alongside computational model design, optimization, and analysis - empowering the design of a better wet lab experiment, followed by a better computational model, back and forth until science is done!
Bachata Fusion With Abraham (Level 2)
[Book Your Classes by Clicking This Link! ](https://crowndancestudio.com/group-classes/)
Take a deep dive into the world of Latin rhythm with our **Level 2 Bachata workshop from 1:30 PM to 3:00 PM**. This 90-minute intensive is crafted for dancers who have moved past the basics and are ready to refine their body mechanics, intricate footwork, and partner connection. **For $25,** you’ll receive focused, high-value instruction that bridges the gap between foundational steps and social dance mastery, ensuring you leave the studio feeling confident and inspired
Waterfront Dinner Viola's + Live Jazz
Hey Social Hub fam! Let’s set the tone this weekend with a smooth, grown‑folks night out. We’re starting with dinner by the water at **Vola’s Dockside Grill**, then sliding over to **Basin Street Lounge** for live jazz to keep the vibe flowing.
After dinner → **🎷 Basin Street Lounge** Live jazz • Cozy atmosphere
Come out for:
• Waterfront views + good food
• Strong drinks + easy conversation
• Smooth jazz after dinner
• Grown‑folks energy all night
Let’s make it a whole vibe.
Sold Out: Make Custom Sneakers
Step into style with this unique and creative workshop led by Susanne! In this class, you'll learn how to turn a simple quilted sandwich made from fat quarters (completed prior to class) into a fabulous, one-of-a-kind pair of quilted sneakers. From the sole up, you’ll stitch, shape, and strut your way through the process — walking away with handmade kicks that are as bold and original as you are! Your registration fee includes the $60 cost of the sneaker soles and a supply kit from Susanne. Note: **students MUST** **register and email your sole size & color choice** **to Susanne by Wednesday, May 27 so she can order the sneaker soles from Europe** in time for class.
For more information and to sign up, **[visit our website »](https://artisticartifacts.com/products/june-20-snazzy-sneakers-with-susanne-miller-jones)**
***
Due to the size or other requirements of the class or concurrent scheduling, some classes are in our second-floor space: access is via stairs only. Registrations for all Artistic Artifacts classes MUST be paid for through our website at [https://artisticartifacts.com/collections/wk](https://artisticartifacts.com/collections/wk), or via a visit to our shop at 4750 Eisenhower Avenue. We encourage you to RSVP here, but to ensure your seat you MUST follow through via our website. View our complete class policies » [https://artisticartifacts.com/pages/class-policies](https://artisticartifacts.com/pages/class-policies)
The Let Go: Friday Night
Let go of the week and welcome the weekend. Join master teacher Ann Kite **in person every Friday** at 8pm for a dynamic, deeply embodied release.
Each week, 60–75 people gather to dance together in a supportive, spirited community. Ann has held this group for years, creating a **safe space to sweat, shift, and soften** the ego’s grip so the freer, wilder, more alive part of you can come through.
Movement is for everyone, whether you’ve danced for years or are brand new. This **isn’t about performing or getting the “right” steps.** It’s about tuning into your body’s natural rhythms, finding freedom in stillness and motion, and remembering what it feels like to be fully alive.
Whether you’re seeking connection, healing, or simply a fresh perspective, you’re **welcome exactly as you are**.
Movement is the doorway. We’ll guide you the rest of the way.
**Purchase tickets:** [https://www.annkite.com/letgo](https://www.annkite.com/letgo)
\*\*\*\*\*Feb 27, Apr 1, Jun 26, Aug 28, and Oct 9, will be led by a substitute teacher as Ann will be away leading a retreat on those dates.
Game Development Working Session (West End Neighbourhood Library Conf Room 2)
NOTE: This working session is at West End Neighbourhood Library not MLK. It is near the Foggy Bottom Metro Station.
A game development **Working Session** involves 3 key parts:
1. Tell people what you're going to do
2. Actually do stuff
3. Show people what you did
**What to bring**: Laptop, Charger, maybe a power strip if you have one handy, any other game development tools you need. Try to download any software you need before the working session. There is Wifi at this location, but it may be slow if you have to download any large files.
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JAMS Meeting: a creative mixed media group!
Join us for **[Judy’s Altered Minds](https://artisticartifacts.com/pages/judy-s-altered-minds)**! Bring your fiber & mixed media show & tell; many members also enjoy making ATCs (**[artist trading cards](https://artisticartifacts.com/pages/judy-s-altered-minds)**) for exchange each month. **Come early to shop** (JAMs attendees receive a 10% discount on their purchases) — Artistic Artifacts is open Sundays 11:00 am - 4:00 pm. The JAMs meeting starts at 1:30 pm. New members are always welcome! A $3.00 contribution is requested at each meeting.
JAMs members are art quilters, collage artists, art journal keepers, surface design enthusiasts, paper crafters, art doll/assemblage artists and more! All levels of expertise are represented, and all are welcome. During JAMs meetings, attendees gather support and encouragement for their art through show & tell and enjoy the camaraderie of like-minded friends.
Next Piano Meeting
Hello piano players:
Our next meeting will take place on Sunday, June 21 from 1:00 P.M. to 5 P.M. at the home of Jerry Butters at 5910 Cromwell Drive in Bethesda, just a few blocks from my house. There is ample street parking within a block or two of his house. Thank you for hosting, Jerry!
Jerry will open his door at 12:30 if you would like to warm up on his piano. It is a Steinway C, made in Hamburg, Germany. It is in a small music room but adjoins another room where there is overflow seating available.
Also, reach out to a friend and work up a duet—they are fun and always welcome. In the past we have had duets with two pianos, with singers and with the clarinet. They bring a nice variety of music to our meetings. It would be nice to expand to string instruments as well.
We will have snacks, finger food, and light drinks, but your donations of food and drink are always welcome. We hope you can attend on the 21st.
Jerry is looking forward to hosting.
Regards,
Paul and Jerry
2 ways to RSVP - Jam in the Park! All skill levels
**Info below: Download Songbook, Safety, Seating, Check Weather**
**RSVP**: There are 2 ways to RSVP - through Meetup (preferred) or through our website [thedcjam.com](www.thedcjam.com)
*When you RSVP, you encourage current and new members to join when they see the number of participants.*
***
**ALL Jammers! All Instruments! All Skill Levels Welcome!**
JOIN US FOR A JAM - IT IS A GREAT WAY TO:
* Get in some practice time
* Learn new songs
* Socialize with other musicians
* Build your confidence
Come join us make music together!
Anyone who can play any instrument at any skill level is welcome to stay and play for some or all of the Jam. We all play and sing songs from our song books of lyrics and chords. Everyone gets a chance to pick a song or pass. No pressure!
***
**a. BRING SONGBOOKS: Please DOWNLOAD our TWO song books.**
Download our TWO song books: at https://www.facebook.com/groups/mhpjam/files/
b. IMPORTANT **SAFETY** INFORMATION
Safety is our number one priority! We want to be sure everybody attending the jam understands personal responsibilities to keep themselves and others safe.
By attending this event you agree to the terms of the HEALTH AND SAFETY WAIVER which can be found in any one of the following:
1. At this link: https://www.facebook.com/groups/mhpjam/permalink/2276132525918969
2. At this link: https://www.dropbox.com/scl/fi/gzfqo4fnw0a2268zr95nx/MITCHELL-PARK-JAM-HEALTH-AND-SAFETY-WAIVER-RELEASE.pdf?rlkey=gztmv5k1shtxunjkc40hj5ij6&st=rek95rkg&dl=0
Please let me know if you have any questions or concerns. Only people who are fully vaccinated can attend. Local laws allow for some exceptions to this rule. Please contact me if you fall under these exceptions so we can make the appropriate arrangements. All members should follow CDC and Washington, D.C. guidelines. In addition, please respect other members needs for space.
***
c. **FACEBOOK**: Join the Facebook group at https://www.facebook.com/groups/mhpjam/
***
d. **SEATING**: You may want to bring a chair as seating may be limited.
***
e. **LOCATION**: The jam will be held at Mitchell Park in Washington, DC. You can find our exact location on this map: https://bit.ly/mhpjamloc1
f. **WEATHER**: Please check your email before you head to the jam in case there is a change due to the weather,
***
g. **DONATIONS**: Suggested donations: $2 per jam -OR- $5 per month -OR- $20 per 6 months. You can Venmo @Eric-Cohen-114
Meetup costs money. Eric pays for most of the costs out of his own pocket, but he asks you to help defray some of the costs with a small donation. Thank you.
Image by rahu\ (https://pixabay.com/users/rahu-4725201/?utm_source=link-attribution&utm_medium=referral&utm_campaign=image&utm_content=2912447) from Pixabay\
Beginner Salsa Classes at Crown Dance Studio.
This is an absolute beginner Salsa group class. It is specifically designed for those with no prior experience in Salsa and participations does not require having a partner.
Every Other Sunday:
$25 per person.
[Click Here to Sign Up](https://crowndancestudio.com/)
2:00 pm to 3:30 pm Beginner Bachata.
Bowie Sci-Fi/Fantasy Game Factory
Playtesting Agent and Battle-scale of the Zone-17 role-playing and miniatures game.
The Power of the Subconscious Mind
**THE POWER OF THE SUBCONSCIOUS OVER YOU**
You are welcome to arrive 15 minutes early for refreshments!
At the lecture "The Power of the Subconscious", the speaker will clearly and understandably explain topics such as:
* What is the exact definition of the Subconscious Mind?
* How does it inflict unwanted feelings and anxiety in you?
* What determines how much pressure it exerts on a person?
* What exactly is the goal of the subconscious?
This is not just a lecture where you sit quietly and listen. It's interactive and LIVE, so you can ask questions at any time.
And the most important topic:
**HOW DO YOU TAKE CONTROL OF YOUR SUBCOUNSCIOUS!**
This group is sponsored by the Dianetics Life Improvement Center.
Cuban Salsa/Rueda de Casino Class & Social Dancing
Danceintime runs Cuban Salsa Classes & Social Dancing Every Saturday, all year-long. Come at 1:15 pm to sign in. Stay till 4 pm.
Some of us go out for coffee or a bite to eat afterwards and everyone is welcome!
$15/person. Cash, PayPal, Venmo, Apple Pay, or Card accepted.
Chevy Chase Baptist Church; 5671 Western Ave. NW; Washington DC 20015. NOTE: Enter through back corner door of the church.
Danceintime classes are great fun. The dance moves are beautiful, fun, and our class creates a bonded community... Check it out! Class will be held every Saturday in December....celebrate the holidays with dance!
For more info: danceintime.com/classes
Questions? Contact Barbbernsteintalks@gmail.com
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Customize the IDE: Building Extensions for Visual Studio Code - Alan Barber
**Important time note:** Please plan on arriving between 5:30 and 6:00 as the elevators lock after 6 and you'll need to message us and we'll need to come get you.
The building address is 4450 Bridge Park
The entrance is 6620 Mooney St, Suite 400
You will need to scan your ID at the door to get a visitor badge.
**Abstract**
*Customize the IDE: Building Extensions for Visual Studio Code*
Visual Studio Code is one of the most widely used development environments today, and much of its flexibility comes from its extension ecosystem. Extensions allow developers to customize the editor with new features, integrations, and workflow improvements tailored to their needs.
In this session, we’ll cover what extensions are and the different types available, including full extensions written in TypeScript or JavaScript, along with lighter-weight extensions such as color themes, language packs, language support, code snippets, and keymaps. We’ll also look at practical reasons a developer might create an extension, from automating repetitive tasks to adding custom tooling.
The session includes a hands-on walkthrough of creating a new extension, testing it locally, and understanding the basic project structure. We’ll close with a brief overview of how extensions are packaged and published to the Visual Studio Marketplace and other distribution options.
**YouTube Link**
TBD
Microsoft Build - Columbus Edition!
We are bringing Microsoft Build sessions to Columbus Ohio!
The Central Ohio Azure Meetup and Central Ohio .NET Developer's Group (CONDG) are coming together to bring some of the labs and breakouts from Microsoft Build to your backyard. In this free, 1 day event, you are going to Build stuff with us!
And yes, there will be free food.
Please RSVP via [Microsoft Build //localhost:columbus | Microsoft Reactor](https://developer.microsoft.com/en-us/reactor/events/27247/).
Columbus Code & Coffee 87 @ Improving
Columbus Code & Coffee is an inclusive, informal co-working session. People of all skill levels attend, and we love it that way. Many people (optionally) bring projects to work on, and many other people (optionally) socialize the entire time. It's entirely up to you!
**What to Expect at the Intro Circle**
\~\~\~\~\~\~\~\~\~\~\~\~\~
Near the beginning of the event (1:30 pm), we do a standup:
* Organizer announcements, updates, and logistics
Round 1 - (7 secs max):
* Your name
* What you're working on
* What you can help others with
Round 2:
* Community events you wanna plug. If none, that's cool too.
Round 3:
* Job opportunities you're hiring for OR announce that you are looking for one. If none, that's cool.
After the introduction circle, everything is self-organized! Feel free to work alone, pair up, attend one of our workshops/presentations, or mingle!
Wolf’s Ridge at Worthington Inn
Let’s try the newly resurrected Worthington Inn which is being run by Wolf’s Ridge.
Check out the menu: https://www.worthingtoninn.com/
Reservation is under Suzie Rao
AI Improv: let’s build a game together with Claude Code, Codex, and Gemini and b
We are going to build together with all the CLIs! E will be doing it at Columbus Code and Coffee
Agenda
---
Hosted By
James Power, Organizer
Pete Gordon, Organizer
Just a Software Guy in the age of the Internet.
Complete your event RSVP here: https://gdg.community.dev/events/details/google-gdg-columbus-presents-ai-improv-lets-build-a-game-together-with-claude-code-codex-and-gemini-and-be-the-judge/.






















