BioInformatics

This month we’ll be reading Goddess of the River by Vaishnavi Patel. Feel free to come even if you don’t finish the book!

Dodgeball is back again! If you’ve been wanting to come out, this is an easy one to join. We’ll be playing for about 1.5 to 2 hours, you do not need to bring any equipment, and no experience is needed. We use a specific set of rules and equipment to make the games run better and keep them fun for everybody, not just people who already know how to play. If it rains, the event will be canceled.

**Synchronicity: Coincidence or Divine Guidance?** Have you ever experienced a “coincidence” that felt too perfect to ignore? A chance encounter, repeated sign, or unexpected moment that seemed to arrive right on time? Join us at Unity of Columbus as Michelle Harcha explores the mystery of synchronicity and how these meaningful moments may be guiding us toward greater wisdom, purpose, and connection. After Sunday’s message, stay for an interactive workshop where Michelle will share practical tools inspired by Byron Katie and Marilee Adams to help us recognize and align with Divine guidance.

**This event is 2:30 - 4 pm Sunday.** Conversation tends toward intermediate/advanced, but everybody is welcome. If you come and don't see us right away, keep looking. We could be anywhere in the restaurant. Or out on the patio.

**Join us for an afternoon of community art and craft time!** Whether you are looking to carve out dedicated creative time, wanting to get a lingering project across the finish line, or just looking to chat with fellow local makers—this is the space for you. 🧵 **What to Bring** Bring any art or craft project you are currently working on, as long as it is portable and quiet. Think: * **Yarn & Thread:** Knitting, crochet, embroidery, cross-stitch, hand-sewing, mending. * **Paper & Sketching:** Sketchbooks, adult coloring books, watercolors, bullet journaling. * **Digital:** Tablets, iPad drawing, laptop writing/design. * *Please note: Because we are meeting in a shared public space, no power tools, sewing machines, or high-odor materials (like strong solvents or spray glues), please!* **📍 Where to Find Us** * We will be meeting at **Columbus Metropolitan Library - Hilltop Branch** in **Meeting Room 4**. Room is reserved under **CBUS Maker Meetup.** **⏱️ Timeline** * **1:00 PM:** Arrive, grab a seat, get settled, and do a quick round of introductions so we can see what everyone is working on. * **1:15 PM - 3:00 PM:** Open maker time! Chat, craft, relax, and swap creative ideas. **⚠️ A Note on RSVPs** The RSVP count for this event is strictly limited to 10 spots. If your plans change and you can no longer attend, please update your RSVP to "Not Going" as soon as possible so someone on the waitlist can grab your spot. Please try to give at least 48 hours' notice if you need to cancel, allowing folks on the waitlist time to check their schedule. *** **We can't wait to meet you and see what you're making! All skill levels welcome.**

Based on the novel Roadside Picnic, it is NO picnic, but rather one of the masterpieces of world cinema. Andrei Tarkovsky's 1979 Soviet sci-fi classic, recounts the expedition of a writer and professor led by a mysterious guide called "The Stalker." to a futuristic wasteland called "The Zone." Dripping with existential dread, it continually presents strange occurrences that will have us debating the meaning of what we've just viewed right through the ending. *Stalker* (1979) can be streamed for free on HBOMax, the Criterion Channel or Kanopy. It's also available for rent on Amazon Prime and AppleTV. The Columbus Library has two copies on disc.

**Latest Dojo Location!** **Knotty Pine Brewing** 1765 W 3rd Ave, Columbus, OH 43212 We're going to try a new dojo location for a few weeks and see how it works Dojos are informal Python group study sessions where everyone interested in Python gathers to learn about Python, help others with Python, or just hang out. Everyone is welcome from Python beginners to experts. Bringing a laptop is encouraged (we'll have extension cords and power strips). If there's something you want to learn leave a comment on this invite so we can plan ahead. We're looking for speakers for our Monthly Meetups! Fill out the form if you are interested in presenting to the Python Community. https://forms.gle/ehSfUAC2WgR34Crq9

**Improving Office in Franklinton** Physical location: Improving Office 330 Rush Alley Suite #150 Columbus, OH 43215 Schedule: 6:00 p.m.: Socialize, eat, and drink. Improving will be providing pizza and beverages. 6:30 to 8:00 pm. Main meeting and presentation(s). Topic: This month Chris Pazsint will be talking about Agentic Coding. How does one use CLI Based Agents, and Agentic IDEs such as Cursor, Kiro, Antigravity? How to include agentic coding plugins for IDEs you already love such as Visual Studio Code. We meet on the last Monday of each Month. Presentations are given by members and friends of this group. If you would like to do a presentation (small or large) on a python topic, please contact Central OH Python at centralohpython@gmail.com

*Sorry for the 2 month break but I had to deal with some family member health issues, but we are now back!!* **LOCATION - THE DAILY GROWLER -** **2812 Fishinger Rd, Upper Arlington, OH 43221** Over the years, we’ve heard two requests constantly: 1. A place that was quieter and possibly private. 2. “I wish they accepted Bitcoin.” We’ve finally found a solution to these requests with The Daily Growler. We’ll have access to their private room, and you’ll be able to pay your tab with Bitcoin. Join us for a fun and relaxed social event! Enjoy delicious food and drinks as we chat about the latest news in the Bitcoin world. Everyone is welcome, whether you're looking for guidance, have questions, or just want to meet like-minded people. These social evenings are a great opportunity to make new friends and enhance your experience at the larger events throughout the year. We look forward to seeing you there! PSA: If the attendee RSVP seems low, keep in mind that most of our attendees come from X and not [meetup.com.](http://meetup.com./) You are welcome to come and become a part of our online community. Recordings of past guest speakers are available on our YouTube channel [https://www.youtube.com/@columbusbitcoin](https://www.youtube.com/@columbusbitcoin)

Most people use LLMs by feel: ask a question, read the answer, decide whether it “seems good,” and move on. That works for casual use. It does not work when you are building software, automating workflows, writing important documents, or relying on AI for anything that needs to be repeatable. In this talk, we’ll look at how to improve and evaluate the inputs and outputs of LLMs using practical measurement techniques. We’ll cover how prompt changes affect results, how to compare outputs, how to build simple evaluation sets, and how math-based methods like similarity scoring can help you move beyond guesswork. This will be beginner-friendly, so even if you don't know anything about AI, you should get something out of it. However, this will be a little more technical than our intro talks. You do not need to be an AI researcher, but programmers and technically curious attendees will get a lot out of it. We’ll cover: * Why “it looks good” is not enough * How to improve prompts by changing the input, context, and constraints * How to compare LLM outputs more systematically * Basic evaluation techniques for accuracy, consistency, and usefulness * How embeddings, cosine similarity, and scoring can help evaluate results * Where automated evaluation works — and where humans still need to stay in the loop By the end, you’ll have a practical mental model for treating LLMs less like magic and more like systems you can test, measure, and improve. LOGISTICS AND PARKING: The talk starts at 7:00 PM. The first half hour is reserved for everyone to get set up and mingle. Free pizza and drinks! The cheapest parking option is to find street parking, which will only cost you a few bucks. Otherwise, park in the nearby veteran's museum lot for $8. It's highly recommended you avoid the nearby $15 garage parking.

*Sorry for the 2 month break but I had to deal with some family member health issues, but we are now back!!* **LOCATION - THE DAILY GROWLER -** **2812 Fishinger Rd, Upper Arlington, OH 43221** Over the years, we’ve heard two requests constantly: 1. A place that was quieter and possibly private. 2. “I wish they accepted Bitcoin.” We’ve finally found a solution to these requests with The Daily Growler. We’ll have access to their private room, and you’ll be able to pay your tab with Bitcoin. Join us for a fun and relaxed social event! Enjoy delicious food and drinks as we chat about the latest news in the Bitcoin world. Everyone is welcome, whether you're looking for guidance, have questions, or just want to meet like-minded people. These social evenings are a great opportunity to make new friends and enhance your experience at the larger events throughout the year. We look forward to seeing you there! PSA: If the attendee RSVP seems low, keep in mind that most of our attendees come from X and not [meetup.com.](http://meetup.com./) You are welcome to come and become a part of our online community. Recordings of past guest speakers are available on our YouTube channel [https://www.youtube.com/@columbusbitcoin](https://www.youtube.com/@columbusbitcoin)

Want to be a speaker? submit your talk to our Call for Presenters!!! https://sessionize.com/azure-cbus-2026/

We have moved to guild.host. Look us up there. https://guild.host/events/buckeye-cocoaheads-rcavwd