BioInformatics

Hi folks! Welcome to our April Cloud Native London meetup! Join us to hear from our three great speakers and network with your fellow techies over pizza and drinks, or alternatively chat and following along on Youtube or LinkedIn! 6:00 Pizza and drinks 6:30 Welcome 6:45 From "Trust Then Verify" to "Verify Then Trust": Securing the AI-Accelerated Software Supply Chain (Meghan McGowan, Cloudsmith) 7:15 Keeping Up: Testing in the Age of AI and Cloud-Native (Ole Lensmar, Testkube) 7:45 Wrap up See you there! Cheryl (@oicheryl) **From "Trust Then Verify" to "Verify Then Trust": Securing the AI-Accelerated Software Supply Chain (Meghan McGowan, Cloudsmith)** With AI accelerating code generation and GitOps driving continuous deployments, testing is under more pressure than ever to keep up. Ole will take a step back to see what’s driving the evolution of testing as adoption of Cloud Native technologies and AI for code generation attempts to drive velocity through the roof. How can engineering and platform teams deliver on the need for continuous testing as a scalable approach to quality assurance across the enterprise? And how can DevOps teams leverage AI in testing pipelines for root-cause analysis, automated remediation and intelligent test scheduling - to help push the AI-infused velocity of their dev teams all the way into production? *Ole started building with XML APIs in the late 90:ies and has since then worked with multiple technologies and startups, most notably as creator of SoapUI in 2004 and Chairman of the Swagger / OpenAPI Initiative in 2015. He joined Testkube at its inception in 2021 and is now entirely focused on ensuring its success at bringing continuous testing to the cloud-native space. When not at his laptop he can be found playing a guitar or riding a bike, but rarely both at the same time.* **Keeping Up: Testing in the Age of AI and Cloud-Native (Ole Lensmar, Testkube)** AI has made software teams faster than ever, but it's also quietly outpacing the security and infrastructure built to support them. Drawing on findings from Cloudsmith's 2026 Artifact Management Report, a survey of 505 engineering practitioners across technology, finance, healthcare, and retail, this session examines the compounding challenges that come with near-universal AI code adoption: expanded attack surfaces, hallucinated dependencies, fragmented AI model governance, and the growing operational tax of manual security remediation on top of aging infrastructure. The session moves from data to diagnosis to direction, challenging teams to rethink a foundational assumption — that you can trust code first and verify it later. At AI scale, that posture is no longer safe. Attendees will leave with a clear picture of where the industry's most critical gaps are, how their peers are investing in 2026, and three concrete questions they can bring back to their own teams to identify where to act first. *Meghan McGowan is Principal Product Marketing Manager at Cloudsmith. Before joining Cloudsmith, Meghan spent nearly a decade in the cybersecurity industry focused on security integrations and automation, helping teams operationalize tooling that actually fits their workflows.* *Based in London, she also worked closely on how threat intelligence can be applied to meet specific regulatory requirements, particularly NIS2 and DORA, giving her a grounded understanding of both the technical and compliance dimensions of modern software security.*
 *About Cloudsmith: Cloudsmith is a fully managed, cloud-native artifact management platform that gives engineering teams a single, secure source of truth for all their software artifacts: packages, containers, binaries, and AI/ML models. Built for the scale and speed of modern software delivery, Cloudsmith provides universal repository support, automated security scanning, and policy enforcement at ingestion needed to meet today's compliance requirements.* *[https://www.linkedin.com/in/meghan-mcgowan-4b6bb81b/](https://www.linkedin.com/in/meghan-mcgowan-4b6bb81b/)* ***Check out [https://www.oicheryl.com/cloudnativelondon](https://www.oicheryl.com/cloudnativelondon) if you're interested in speaking or sponsoring.***

Join me for a fun Drama class every Wednesday evening from 6:30 pm- 8:30pm at the Omnibus Theatre in Clapham Common. Acting helps with confidence and awareness. In a fun and relaxed atmosphere, you will meet new people and learn all about Acting. No experience is needed. We'll do relaxation exercises, games, improvisations, storytelling, and a bit later on we'll start working on character and text. The year ends with an exciting Showcase where friends and family come and see how all your hard work has paid off :) £10 pounds for the trial class to be paid before or after class. Different payment options if you decide to join. In order to reserve a place, please contact me at catherine@thebrightdaycompany.net. For more info: https://www.thebrightdaycompany.net/about I look forward to seeing you!

Thank you to everyone who has joined the Agentic community so far and thank you to those who attended the launch event in January! Its exciting times as we now gear up for the 2nd meet up of the year once again hosted by the wonderful team over at Vorboss LTD! We have a stellar line up for you again so please RSVP and join us on 1st April! **Odhran O'Donoghue \| Co\-Founder & CTO @ Magentic** **Making AI with Enterprise-level Reliability** Making AI work in critical business use cases requires superhuman-level reliability. Achieving this with AI is non-trivial, and even advanced developers can find themselves chasing the wrong paths to success. This talk covers how to build genuinely reliable generative AI to meet the needs of the world's largest customers, drawing from learnings on real-world deployments covering billions of dollars in spend. Odhran O'Donoghue is CTO of Magentic, the AI agent platform for the world’s supply chains. The company is backed by Sequoia Capital, used across a range of Fortune 500 manufacturers. Odhran has previously worked with OpenAI and NASA, and led research at the Francis Crick Institute - Europe’s largest scientific centre. **Anastasia Kundush \| Head of Product @ Alpic** **Beyond the Chatbot: rethinking user flows in the agentic era.** Imagine apps that live directly inside ChatGPT or Claude. Instead of clicking buttons, you interact with agentic interfaces. We'll examine novel use cases where models seamlessly adopt complex roles and merge interactive visualizations with conversational insights. You'll learn how to design for this new paradigm and what doesn't work. Alpic provides the infrastructure and tools to turn your product into an AI-native experience. Our all-in-one MCP hosting platform offers easy one-click deployment, as well as MCP-specific evaluation, analytics, authentication, transport and security. A huge thank you to Odhran and the team at Magentic for sponsoring pizzas and also a big thank you once again to Vorboss for hosting and supplying drinks for all attendees on the night :)

Wir treffen uns wieder in Queen's Head, nicht weit weg von den U-Bahn Stationen Hammersmith und Kensington Olympia. **Achtung:** Im März hatten wir eine hohe Anzahl der No-shows, daher habe ich die Anzahl der Teilnehmer reduziert. **Bitte meldet ihr euch an nur wenn ihr wirklich kommen könnt** und meldet ihr euch ab wenn es doch nicht klappt. Deutschprachige jeder Stufe herzlich willkommen. \-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\- Please note that you're attending the event at your own risk. The event organiser won't accept any risk or liability at this event.

Its Springtime, and the gardens and landscape are bursting into life! To celebrate this in our digital world, 3D London has partnered with ITOOSOFT, the makers of ForestPack, to bring you an evening of 3D horticultural inspiration. **Headline Presentations** * **Paul Roberts**, Training and Content Manager - ITOOSOFT "The Craft of Parametric Thinking" https://www.itoosoft.com/ * **Karen Gazzard**, The Ruby Cube. "How I have taken the skills learnt in arch-vis and applied them to a different industry - visualisation for ecology." https://therubycube.com/ **First-time Presentation** **Alesandros Vounatsos** \- Alvo Headquarters Production Company "Presenting his short film, produced in Blender". https://www.linkedin.com/in/alexandros-vounatsos-aa3b3175/ The ITOO team kindly sponsored April's meetup. Thank you! Thanks to our sponsors for supporting our monthly meetups. **[SiNi Software](https://www.sinisoftware.com/)** , **[Chaos](https://www.chaos.com/) , [ITOOSOFT](https://www.itoosoft.com/) , [NTI](https://www.nti-group.com/uk/) , [Heata](https://www.heata.co/)** #3dlondon #monthlymeetup

**FREE - Build an App Using AI** **beginner-friendly workshop · no coding experience needed** (for complete beginners to experts) **build a working app in under 2 hours using ai & chatgpt** bring your laptop and we’ll build step by step from scratch *stop thinking about AI and start making something* **what this is** a hands-on ai app-building workshop **the vibe** practical, beginner-friendly, collaborative **what’s included** guided build session help throughout something working by the end **who this is for** people who are curious about ai but don’t know where to start **how it works** arrive, follow along, build together, ask questions **abdullah tahir (your instructor)** masters in ai + professional data scientist & comedian loves building with people specialist in making technical ideas feel approachable and fun **location** the tankard, kennington - private dining room workshop begins 7pm, finishes 9pm **why this one matters** you leave with something real, not just ideas **final note** no coding experience needed see you there 💻 p.s. by attending, you agree to our [event terms & conditions](https://docs.google.com/document/u/2/d/e/2PACX-1vS3p3ZAhIoCyq3kHFEliu2NCaT8iHfz5E_nUxcUTr7rsDufU7x5BNB_Ta2BWqtTYX72rEAjBG2nOcze/pub)

Welcome to our second London meetup of 2026, where we discuss Gen AI and Kubernetes! Details below: **Location:** Civo Tech Junction, First Floor, 32-37 Cowper St, London EC2A 4AW **Time:** Doors open at 6PM **Drinks, snacks, talks, and networking.** We’re excited to invite you to our second in-person **DevOps Society Meetup** of 2026, proudly **sponsored by Cast AI**. This event is focussed around Gen AI and Kubernetes, with two really exciting speakers lined up for this one in Carly and Kunal. Format of the Meetup: 6:00pm – 6:30pm — Networking on arrival, with food and drinks provided by CastAI 6:30pm – 7:10pm — First speaker + Q&A 7:10pm – 7:20pm — Break for refreshments and networking 7:20pm – 8:00pm — Second speaker + Q&A 8:00pm onwards — More networking at the venue, then at a nearby pub. *Timings can vary slightly depending on Q&A.* We’re excited to welcome everyone to our next DevOps Society London meetup, where we’ll be diving into two incredibly relevant topics in modern infrastructure: observing GenAI applications in production and optimising Kubernetes clusters. We’ll be joined by two brilliant speakers from the ecosystem who are working at the forefront of developer tooling and cloud infrastructure. As always, expect a relaxed evening of technical learning, discussion, and networking with fellow engineers from across the London tech community. *** ## 🎤 Speaker 1 - Carly Richmond **Developer Advocate Lead @ Elastic** ### Observing AI Applications with OpenLit and OpenTelemetry Observability is the ability to measure the current state of a system. With the rapid emergence of LLMs and GenAI applications moving into production, teams now need deeper insight into how these systems behave in real-world environments. In this talk, Carly will explore best practices for observing production AI applications, covering how engineers can capture logs, traces, and metrics to better understand how LLMs interact within their application ecosystem. She’ll walk through a real example of instrumenting an AI agent application written in TypeScript, using OpenLit to generate OpenTelemetry signals. The session will show the types of telemetry data teams can capture to identify usage patterns, detect errors, and troubleshoot issues commonly seen in production GenAI applications. ### About Carly Carly Richmond is Developer Advocate Lead at Elastic, based in London. She’s a UI developer who also writes backend services, a keynote speaker, and a tech writer who is passionate about helping developers build better systems. Outside of tech, Carly enjoys cooking, photography, drinking tea, and chasing after her young son. *** ## 🎤 Speaker 2 - Kunal Kushwaha **Senior Developer Advocate @ CAST AI** ### Optimizing Kubernetes and Unlocking Blockers with Container Live Migration Kubernetes promises automation, yet most clusters run at around **10% CPU utilisation**, leaving large amounts of infrastructure sitting idle. With endless instance types, constantly shifting prices, and the complexity of modern workloads, maintaining efficient clusters can quickly become a full-time job. In this talk, Kunal explores the real-world challenges teams face when running Kubernetes in production. He’ll cover where Kubernetes automation works well, where it falls short, and why optimisation remains difficult for many teams. Topics include: * Why most Kubernetes clusters are underutilised * The realities of autoscaling in production environments * Challenges around instance types and Spot capacity * Common mistakes teams make with HPA and VPA Once these challenges are laid out, Kunal introduces Container Live Migration as a way to overcome some of these long-standing blockers. To bring the concept to life, he’ll run a live technical demo where Pods running a small video game are migrated across nodes in real time, while the audience participates. The game continues running without downtime, demonstrating how live migration can improve cluster efficiency without disrupting workloads. Please register below to secure your spot. Spaces are limited and available on a first-come, first-served basis. We’re really looking forward to getting the community back together again for our first event of 2026. [Our slack community](https://join.slack.com/t/devopssociety/shared_invite/zt-3mswuylw7-MhJg1IZ70rX_GpJTluG2Cw) \- join in and introduce yourself\! [Our Youtube Channel ](https://www.youtube.com/@DevOpsSociety)for regular podcasts with DevOps professionals + more DevOps content. [Website](https://thedevopsociety.com/) [To partner with us](https://thedevopsociety.com/partnerships) CAST AI website - https://cast.ai/ Thanks! From the DevOps Society team [Ben](https://www.linkedin.com/in/benwhitmarsh/) and [Vytas](https://www.linkedin.com/in/vytasdevops/)

Our THURSDAY EVENING Session and social is primarily for Club Members but guests are welcome. It is aimed at Players of INTERMEDIATE LEVEL AND ABOVE. We would like to keep the level above intermediate. Anyone below this level may be asked to attend coaching sessions until they reach the required standard There is coaching available for beginners and players of all levels. The session will be run as follows. Courts 1 and 2 Games Court 3 Coaching & Drills If you believe you should be playing at a higher level I will be pleased to assess your game. Please respect the way the session has been planned. Any deviation from this and you may be asked to leave. Sometimes team members will need to practice together. If you are interested in trying out for one of our many league teams please let Mani know. Places may be restricted if a match is being played. The cost for this session is £13 MEMBERS WILL ALWAYS BE PRIORITISED WHEN SIGNING UP FOR SESSIONS. **THERE IS A 12 HOUR CANCELATION PILICY. IF YOU CAN'T MAKE IT PLEASE UPDATE YOUR RSVP TO NO 12 HOURS BEFORE THE SESSION. ANY TIME UNDER 12 HOURS AND YOU WILL BE RESPONSIBLE FOR PAYMENT AND UNABLE TO RSVP AGAIN UNTIL PAYMENT IS CLEARED** PLEASE BRING DRINKING WATER TO STAY HYDRATED AS ACCESS TO WATER FOUNTAINS MAY BE RESTRICTED. PLEASE PAY WHEN YOU RSVP TO GUARANTEE YOUR SPOT. I WILL NOT BE TAKING CASH PAYMENTS FOR THE TIME BEING. PAYMENT DETAILS Use Payment link https://monzo.com/pay/r/storm-bc_lDA87GJFk9hkqt Or Monzo Bank Storm BC 04-00-03 77638837 Thanks and see you on court.

We are excited to announce our upcoming Spring Community Showcase. This event is an opportunity for individuals at all skill levels to come together and share their experiences with Rust. Whether you’re working on a personal project, contributing to an open-source initiative, or teaching a concept related to Rust, we invite you to present your work and insights. Take this opportunity to build your confidence and share what you are doing. Speakers === If you would like to give a presentation, please send Ernest a direct message with your talk title and a brief abstract of approximately 60 words. Each presentation will last about 25 minutes, followed by 5 minutes for questions and answers, for a total of 30 minutes. We have four slots available this month. **Dan Groshev** Okmain Library: You have an image, but you want a colour How do you pick a colour that represents an image but also looks good? Dan will talk about his Okmain library, colour science, auto-vectorisation, SIMD, and his experience building it in Rust and PyO3. **Jérôme Étévé** Mockapot: A percolator library in Rust Jérôme is the author of the Mokcaccino library, which started as a way to marry my interests for Rust and for search technology. He will discuss the design, the tricky aspects of Rust he learned along the way, and how Rust and Python complement each other. **Evadne Wu** JavaScript Sandboxing using Deno on top of Elixir & Erlang/OTP. Intelligent AI agents can write code that calls existing APIs in secure sandboxes, allowing higher token efficiency, better performance, and lower per-turn latency. Deno’s primitives in Rust can be integrated into such an agent harness, utilising the Elixir programming language and the Erlang/OTP runtime, which allows you to construct agentic systems that are massively concurrent and fault-tolerant.

Our Sunday afternoon Session and social is primarily for Club Members but guests are welcome. It is aimed at Players of IMPROVER TO INTERMEDIATE ABILITY. NO BEGINNERS ALLOWED. There are 2 courts. Sometimes team members will need to practice together. If you are interested in trying out for one of our many league teams please let Mani know. Places may be restricted if a match is being played. The cost for this session £12 **THERE IS A 12 HOUR CANCELATION PILICY. IF YOU CAN'T MAKE IT PLEASE UPDATE YOUR RSVP TO NO 12 HOURS BEFORE THE SESSION. ANY TIME UNDER 12 HOURS AND YOU WILL BE RESPONSIBLE FOR PAYMENT AND UNABLE TO RSVP AGAIN UNTIL PAYMENT IS CLEARED** PLEASE PAY WHEN YOU RSVP TO GUARANTEE YOUR SPOT. PAYMENT DETAILS paypal.me/ManiFrempong Monzo Bank Storm BC 04-00-03 77638837 Thanks and see you on court.

**About this event** Whether you've just heard about OpenClaw or you've been running it for a while, come along and meet your people. This is a relaxed, informal get-together for beginners and experts alike — no agenda, no pressure, just good conversation and a shared love of OpenClaw. Bring your laptop, chat with new friends, swap ideas, and build stuff together. **Cost** Free — no tickets, no fees, just show up.

This a BSL practice group for level 1 students and above. We will be meeting at the national theatre in southbank

In this event, we will discuss about a science or philosophy book chosen by London Science and Philosophy Book Club. The attendees will be divided into groups and each of them will focus on a chapter in the book. This month we will discuss about a fascinating book called Warriors and Worriers by Joyce F. Benenson. If you haven't read the book, it's no problem. I will bring you up to speed with the discussion materials. We will meet in a nice lounge area at 6 p.m for introductions. Please come on time so you will not miss out on valuable discussion midway. If you end up in the waitlist, feel free to show up. Book Description: The question of exactly what sex differences exist and whether they have a biological foundation has been one of our culture's favorite enduring discussions. It should. After a baby is born, a parent's first concern is for its physical health. The next concern is its sex. Only in the most modern societies does sex not virtually guarantee the type of future life a new human being will have. Even in modern societies, one's sex usually plays a large role in the path a life follows. Scientists have published thousands of papers on the subject, with the general conclusion being that men and women are mostly the same, whatever differences exist have been socialized, and what differences exist have to do with women bearing children and men being physically stronger. In Warriors and Worriers, psychologist Joyce Benenson presents a new theory of sex differences, based on thirty years of research with young children and primates around the world. Her innovative theory focuses on how men and women stay alive. Benenson draws on a fascinating array of studies and stories that explore the ways boys and men deter their enemies, while girls and women find assistants to aid them in coping with vulnerable children and elders. This produces two social worlds for each sex which sets humans apart from most other primate species. Human males form cooperative groups that compete against out-groups, while human females exclude other females in their quest to find mates, female family members to invest in their children, and keep their own hearts ticking. In the process, Benenson turns upside down the familiar wisdom that women are more sociable than men and that men are more competitive than women. Agenda: 6 p.m to 6:30 p.m: Introduction and Socializing 6:30 p.m to 9:30 p.m: Book Discussion 9:30 p.m to late night: Drinks, Dinner or Feel free to go home.

The Fellowship of the Star Schema: Transforming OLTP Data for Power BI One does not simply build reports on OLTP data. Join us on an epic journey from the depths of raw, normalized tables to the shining halls of a well-modeled star schema fit for Power BI greatness. We will demystify the differences between OLTP and OLAP, walk through star schema vs snowflake (and why Power BI has a clear favorite), and show you the compression differences between normalized and columnar storage that will make you never look at an OLTP model the same way again. We will cover the different types of dimensions, when to use them, and how to handle Slowly Changing Dimensions without losing your mind. You will leave knowing exactly how to identify a bad model, how to convert OLTP data into a clean star schema, and how to forge relationships that rule them all. Whether you are a data wizard, a curious hobbit, or somewhere in between, your models will never be the same.

Pay attention! We’re delaying a week for those of you who may be on Spring break and/or celebrating the holiday. Ok, no pancakes, but waffles-a-plenty. Join the local UX and Digital Design community for a casual monthly breakfast. Look for us upstairs!

## **Columbus Bitcoin Meetup – Event** Join us for another great evening dedicated to Bitcoin, learning, and community. We will be gathering in the private room at Olentangy Brewery for an evening of conversation, education, and fellowship with fellow Bitcoiners. This special event will feature three guest speakers sharing insights from across the Bitcoin ecosystem. ### **Guest Speakers** **Lindsay Faust** Relationship Manager at River **Andrew Tilmann** CEO of the Midwest Bitcoin Summit **Carlos Estrada** Founder of Coin Vigilante In addition to speaking during the event, Andrew Tilmann will also be available for a meet and greet. This will be a great opportunity to ask questions about the upcoming Midwest Bitcoin Summit, taking place September 23 and 24 at the Columbus Convention Center. ### **Midwest Bitcoin Summit Discount** Early Bird pricing ends **April 1st**, but you can still save **21%** by using the promo code: **COLUMBUS** Use the link below to apply the discount: [https://tickets.midwestbtc.com/affiliate/columbusbitcoinmeetup/event/midwest-bitcoin-summit-2026/?promoCodeTask=apply&promoCodeInput=columbus](https://tickets.midwestbtc.com/affiliate/columbusbitcoinmeetup/event/midwest-bitcoin-summit-2026/?promoCodeTask=apply&promoCodeInput=columbus) ### **Event Details** This will be a three hour event, with speakers beginning just before 7:00 PM. There will be plenty of time afterward for networking, meeting new friends, and continuing the conversation. Food will be provided. We look forward to seeing you there! ***

**The Data-Driven Brand: Using Analytics to Shape Perception** Can you use analytics to improve tacos? This being CBUSDAW, we think the answer is probably “yes”, but we’re not sure how to implement or test this theory. For our April meetup we’ve got Sara Kear, CMO of Condado Tacos, to investigate this delicious question. Sara will explore how she blends quantitative data and qualitative customer feedback to shape brand positioning and drive business decisions. We all know that marketing and analytics go way beyond attribution. Sara will show how Condado uses customer insights to inform product and pricing strategy. She’ll also highlight how Condado leverages customer feedback at scale to influence operational priorities, positioning marketing as the voice of the customer across the organization. In the last 12 years Condado has gone from one location in Columbus to 52 locations across 10 states, so we’re guessing there’s more to that growth than really good guac (though the guac probably helps). Ultimately, this talk focuses on the intersection of art and science—using data to inform creativity and build a brand that resonates with customers in a measurable way. **About Our Speaker** Sara Kear is Chief Marketing Officer at Condado Tacos, where she oversees brand, restaurant design, menu and pricing strategy, off-premise including catering, and customer data strategy. Since joining in 2021, she has helped grow the brand from 19 to 52 locations while building a data-driven marketing organization focused on loyalty and customer insights. Condado has since been named to the Inc. 5000, recognized as Breakout Retailer by Chain Store Age, and consistently ranked among FastCasual’s Top 100 Movers & Shakers. Thanks to our 2026 sponsors: [Clarivoy](https://www.clarivoy.com), [What Box Consulting Group](https://www.whatboxconsultinggroup.com), [Conductrics](https://www.conductrics.com), and [Piwik PRO](https://piwik.pro) More info at [cbusdaw.com](https://cbusdaw.com)

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**Latest Dojo Location!** **Knotty Pine Brewing** 1765 W 3rd Ave, Columbus, OH 43212 We're going to try a new dojo location for a few weeks and see how it works Dojos are informal Python group study sessions where everyone interested in Python gathers to learn about Python, help others with Python, or just hang out. Everyone is welcome from Python beginners to experts. Bringing a laptop is encouraged (we'll have extension cords and power strips). If there's something you want to learn leave a comment on this invite so we can plan ahead. We're looking for speakers for our Monthly Meetups! Fill out the form if you are interested in presenting to the Python Community. https://forms.gle/ehSfUAC2WgR34Crq9

Our monthly PHP meetup. A virtual shindig courtesy of Zoom. Check back here for the details around 6:15 pm