Synthetic Biology

**Improving Office in Franklinton** Physical location: Improving Office 330 Rush Alley Suite #150 Columbus, OH 43215 Schedule: 6:00 p.m.: Socialize, eat, and drink. Improving will be providing pizza and beverages. 6:30 to 8:00 pm. Main meeting and presentation(s). Topic: Type Annotations with John Cassidy We meet on the last Monday of each Month. Presentations are given by members and friends of this group. If you would like to do a presentation (small or large) on a python topic, please contact Central OH Python at centralohpython@gmail.com

Main Library, Meeting Room 2B Join us for a welcoming evening of reflection, gentle music, and meaningful conversation. We’ll begin with a short grounding moment, followed by a brief reading from spiritual or philosophical traditions, and an open reflection circle where participants can share (or simply listen). Libera Animae is an interfaith community focused on inner growth, creativity, and authentic connection. All backgrounds are welcome.

**First meetup of the Columbus AI Engineering group.** We’ll kick things off with a practical, beginner-friendly discussion on: **How LLMs like ChatGPT actually work — and how to build real applications with them.** We’ll cover: * what’s actually happening under the hood (at a high level) * why LLMs behave the way they do (hallucinations, prompt sensitivity, etc.) * how people are building real systems with them today * where things break in practice This will be a **short, informal talk (\~15–20 min)** followed by open discussion and Q&A. Whether you’re an engineer, builder, or just curious about how modern AI systems work, you’re welcome to join. No slides, no fluff — just real conversation about real systems. We’ll hang out afterward and get to know each other.

Join us for a flat 2.6 mile hike along the Alum Creek Trail from the rear parking lot of the Easton Hilton Garden Inn to the Strawberry Farms Park and back. This scenic trail along Alum Creek is a gem. Come and hike it with us!

Ciao a tutt\*! Let's meet Monday at 6.30pm at the Upper Arlington Library (**Tremont** Branch) in **Meeting Room A** to speak in Italian for 1 hour.

This is an in-person meeting. At this meeting you will get answers to depression and anxiety. Find out the source of them and how to get rid of them. Did you know that unwanted emotions like anxiety, depression, unhappiness, loneliness, hopelessness, anger, fear, or feelings of irritation don’t just fall on you for no reason. They are not random occurrences that simply happen to people's minds. They are definitely not due to a chemical imbalance in your brain from some nebulous chemical reaction "by chance". Your negative emotions are the symptoms of the painful experiences that you have which are not healed, and which are still affecting you. The effects of these painful experiences are exacerbated by the pressures or difficulties of the other problems in your life. Come to our Meetup, where we can introduce you to some of the knowledge, tools and techniques of the breakthroughs in the field of the mind that we can apply to this ever important area of life. Be sure to click on the red "Attend" button below to come to this local event. We look forward to seeing you there. This group is created by the Hubbard Dianetics Foundation of Central Ohio and Church of Scientology of Central Ohio.

Join us as we get together for an Arthouse Movie Friday event to see the A24 dark comedy /romance / psychological-thriller, THE DRAMA! The film stars Zendaya and Robert Pattinson as a happily engaged couple whose relationship is challenged when one discovers unsettling truths about the other. Here are details, a trailer and our plan for this event: DESCRIPTION: The film follows a happily engaged couple whose relationship is put to the test when an unexpected turn sends their wedding week off the rails. The film comes from A24, is written/directed by Kristoffer Borgli stars Zendaya, Robert Pattinson, Mamoudou Athie, Alana Haim, Hailey Gates and Zoë Winters. QUICK WORD OF WARNING: The film hasn’t screened for critics yet and most of the details are being kept tightly under wraps. But, early buzz (possibly promotional) says the film is a brilliant psychological thriller/romance but also provocative, twisty and some contains occasional uncomfortable viewing! I love the cast and trailer, so look forward to seeing for ourselves! ZENDAYA-PATTINSON TRIFECTA CHALLENGE: Robert Pattinson and Zendaya will star in THREE movies together this year, including THE DRAMA, Christopher Nolan’s THE ODYSSEY this Summer and Denis Villeneuve’s DUNE: PART THREE at Christmas! TRAILER: [https://www.youtube.com/watch?v=6zmKcUa4Xxk](https://www.youtube.com/watch?v=6zmKcUa4Xxk) PLAN: We’ll plan for 7pm-ish showing and will meet in the lobby area about 30 minutes before showtime! Advance ticket purchase not required for this theater but early arrival is advised. Possibly post-movie get-together at the nearby Rusty Bucket! Complete details will be confirmed/announced as the date gets closer. Take care and look forward to seeing you there, Dan

Join us as we get together for a Discount Tuesday / Choose Your Movie event to see your choice of two great films! Option 1 is the dark comedy/drama based on a true story TOW! The film stars Rose Byrne as a homeless Seattle woman how battles a towing company. Option 2 is the off-the-rails, over-the-top, action-comedy-horror THEY WILL KILL YOU! The film stars Zazie Beetz as a woman who answers a help wanted ad to be a housekeeper in a mysterious New York City high-rise not knowing its mysterious past! Here are details, trailers and our plan for this event: TOW: This dark comedy/drama is based on a true story and follows a homeless Seattle woman who fights her way out of "tow-company hell" to reclaim the car that had held her life together after receiving a tow bill for $21,634. The film stars Rose Byrne, Ariana DeBose, Demi Lovato, Octavia Spencer, Dominic Sessa, Elsie Fisher and Simon Rex! The film premiered to solid reviews at last year’s Tribeca Film Festival where critics declared, “TOW is a winner!” It’s “a story of perseverance, heart, and real fight, the kind of small human story we see less frequently these days, but need now more than ever.” TRAILER: https://www.youtube.com/watch?v=qdkpcsuPAhA THEY WILL KILL YOU: A woman takes a job as a housekeeper in a NYC high-rise, unaware of the building's history of disappearances. She soon realizes the community is shrouded in mystery. The film is directed by Kirill Sokolov and Zadie Beetz, Myha'la, Paterson Joseph, Tom Felton, Heather Graham, and Patricia Arquette. The film is being released immediately following its premiere at this year’s SXSW Festival earlier this month. Early reviews say it’s “an adrenaline rush of action-packed fights, tons of blood and gore and plenty of laugh-out-loud moments” and a movie that’s “unafraid to march to its own campy, violent, and clever little drummer!” TRAILER: https://www.youtube.com/watch?v=XYqQPiXpi4w PLAN: Not exactly a “Choose Your Movie” event, more like an early show and a late one (or both if you’re feeling sparky)! \* If you’d like to see TOW, please purchase your ticket for the 5:00pm showing and meet in the upstairs lobby between 4:40 and 4:50pm! \* If you plan to see THEY WILL KILL YOU, please purchase your ticket for the 7:45pm showing and meet in the upstairs lobby between 7:25 and 7:35pm! \* Tickets for both films on sale now and advance purchase is advised! Tickets just $5.00 ($6.50 after online fees when purchased via the GFC website). Once you have yours, please list your movie of choice and seat number in the Comments section of this event. \* Also, as a reminder, close, convenient parking available in the nearby garage (Between 9th and 11th, just off High) and just $2 when you have your ticket validated at the theater! Look forward to seeing you there, Dan

**Join us for a vegan morning at downtown Columbus's premier vegan diner!** * **Date:** Saturday, April 4th * **Time:** 11:00 AM * **Location:** [4th & State](https://www.4thandstate.com/) (152 E State St, Columbus, OH 43215) * **Type:** Community Dining / Brunch * **Cost:** Pay-as-you-go (Entrees typically range from $10–$20) *** **About the Event** Come catch up with fellow vegans and vegan-curious friends in the heart of downtown. 4th & State is a family-owned, "mod diner" known for its laid-back atmosphere and incredibly indulgent vegan comfort food. Whether you’re looking to discuss animal rights activism or just want to enjoy a milkshake with like-minded people, all are welcome! **The Food** This spot is **100% vegan** and offers a massive menu of diner classics. Highlights include: * **Signature Brunch:** The **Vrunchwrap**, pancakes, and French toast sticks. * **Comfort Classics:** Loaded fries, burgers, and their "hand-breaded tempeh chicky." * **Allergen Friendly:** They offer a dedicated **gluten-free** menu and are a **tree-nut-free** kitchen (with the exception of coconut oil). **Important Details** * **Seating & Reservations:** 4th & State typically does **not take reservations**, so please RSVP early so we can try to coordinate seating together. * **Parking:** There is free and paid street parking nearby, as well as several paid parking lots in the downtown area. * **Accessibility:** The restaurant features a wheelchair-accessible entrance and seating.

**Latest Dojo Location!** **Knotty Pine Brewing** 1765 W 3rd Ave, Columbus, OH 43212 We're going to try a new dojo location for a few weeks and see how it works Dojos are informal Python group study sessions where everyone interested in Python gathers to learn about Python, help others with Python, or just hang out. Everyone is welcome from Python beginners to experts. Bringing a laptop is encouraged (we'll have extension cords and power strips). If there's something you want to learn leave a comment on this invite so we can plan ahead. We're looking for speakers for our Monthly Meetups! Fill out the form if you are interested in presenting to the Python Community. https://forms.gle/ehSfUAC2WgR34Crq9

This meeting will be a discussion of the book "the Science of Aliens" by Mark Brake

**The Data-Driven Brand: Using Analytics to Shape Perception** Can you use analytics to improve tacos? This being CBUSDAW, we think the answer is probably “yes”, but we’re not sure how to implement or test this theory. For our April meetup we’ve got Sara Kear, CMO of Condado Tacos, to investigate this delicious question. Sara will explore how she blends quantitative data and qualitative customer feedback to shape brand positioning and drive business decisions. We all know that marketing and analytics go way beyond attribution. Sara will show how Condado uses customer insights to inform product and pricing strategy. She’ll also highlight how Condado leverages customer feedback at scale to influence operational priorities, positioning marketing as the voice of the customer across the organization. In the last 12 years Condado has gone from one location in Columbus to 52 locations across 10 states, so we’re guessing there’s more to that growth than really good guac (though the guac probably helps). Ultimately, this talk focuses on the intersection of art and science—using data to inform creativity and build a brand that resonates with customers in a measurable way. **About Our Speaker** Sara Kear is Chief Marketing Officer at Condado Tacos, where she oversees brand, restaurant design, menu and pricing strategy, off-premise including catering, and customer data strategy. Since joining in 2021, she has helped grow the brand from 19 to 52 locations while building a data-driven marketing organization focused on loyalty and customer insights. Condado has since been named to the Inc. 5000, recognized as Breakout Retailer by Chain Store Age, and consistently ranked among FastCasual’s Top 100 Movers & Shakers. Thanks to our 2026 sponsors: [Clarivoy](https://www.clarivoy.com), [What Box Consulting Group](https://www.whatboxconsultinggroup.com), [Conductrics](https://www.conductrics.com), and [Piwik PRO](https://piwik.pro) More info at [cbusdaw.com](https://cbusdaw.com)

NFT's are here to stay folks! This is a group for like minded people interested in understanding, leveraging, using, creating for, profiting from, trading too i suppose, NFT's.. everything around them, complexity, fear and exploits, best practices and more. **PLUS** This group will talk AI ART tools, techniques, artists, video, audio, prototypes and more in the AI assisted production space- ART specifically, but we can get into any aspect of some of the cooler things happening in AI in general.

Central Ohio Radio Enthusiasts—CORE—is an informal community for anyone enthusiastic or curious about radio—whether you're new to radio and want to learn or you've been tinkering for years and want to share. Ham radio operators, GMRS users, Meshtastic fans, software-defined radio nerds, makers, and technical and non-technical folks are all welcome. No experience required or expected. This month we have **WiFi HaLow: Introduction and Practical Use** with **Alex Barbur**. Details are are [core.radio](https://core.radio).

Pay attention! We’re delaying a week for those of you who may be on Spring break and/or celebrating the holiday. Ok, no pancakes, but waffles-a-plenty. Join the local UX and Digital Design community for a casual monthly breakfast. Look for us upstairs!

Bring your Raspberry Pi, Arduino, microcontroller, or any other electronic project and join fellow electronics makers for a night of creativity and collaboration! This session is open forum to share your current projects—whether complete or in progress, it’s all interesting! Whether you’re deep into embedded systems, exploring new ideas, or just getting started, you’ll find a welcoming space to collaborate, share, and get inspired. **New to electronics or curious about tinkering?** You’re absolutely welcome. If you’re a beginner and want to experiment, I’ll have a couple of starter kits available so you can try things out—whether that’s blinking your first LED, putting something on a display, or experimenting with simple sensors. No pressure and no experience required—just an interest in learning and building. While we continue to pursue a more permanent venue for this Meetup, we’ll be using public library facilities based on availability. This session will be at the Worthington Park Library in the Olentangy Meeting Room.

Want to be a speaker? submit your talk to our Call for Presenters!!! https://sessionize.com/azure-cbus-2026/